Search Results - "Bobzean, Samara A."

Sex differences in the neurobiology of drug addiction by Bobzean, Samara A.M., DeNobrega, Aliza K., Perrotti, Linda I.

“…Epidemiological data demonstrate that while women report lower rates of drug use than men, the number of current drug users and abusers who are women continues…”
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Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo by Deb, Paromita, Bhan, Arunoday, Hussain, Imran, Ansari, Khairul I., Bobzean, Samara A., Pandita, Tej K., Perrotti, Linda I., Mandal, Subhrangsu S.

“…HOXB9 is a homeobox-containing gene that plays a key role in mammary gland development and is associated with breast and other types of cancer. Here, we…”
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Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo by Bhan, Arunoday, Hussain, Imran, Ansari, Khairul I., Bobzean, Samara A.M., Perrotti, Linda I., Mandal, Subhrangsu S.

“…•Long non-coding RNA HOTAIR is a key player in breast cancer.•HOTAIR is induced by endocrine disruptors BPA and DES in vitro and in vivo.•MLL-histone…”
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HOXA5 Expression Is Elevated in Breast Cancer and Is Transcriptionally Regulated by Estradiol by Hussain, Imran, Deb, Paromita, Chini, Avisankar, Obaid, Monira, Bhan, Arunoday, Ansari, Khairul I, Mishra, Bibhu P, Bobzean, Samara A, Udden, S M Nashir, Alluri, Prasanna G, Das, Hriday K, Brothers, Robert Matthew, Perrotti, Linda I, Mandal, Subhrangsu S

“…HOXA5 is a homeobox-containing gene associated with the development of the lung, gastrointestinal tract, and vertebrae. Here, we investigate potential roles…”
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MLL Histone Methylases Regulate Expression of HDLR-SR-B1 in Presence of Estrogen and Control Plasma Cholesterol in Vivo by Ansari, Khairul I, Kasiri, Sahba, Hussain, Imran, Bobzean, Samara A. Morris, Perrotti, Linda I, Mandal, Subhrangsu S

“…High-density lipoprotein receptors scavenger receptor class B type I [HDLR-SR-B1 (SR-B1)] is a key player in reverse cholesterol transport and maintaining…”
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Exposure to morphine-associated cues increases mu opioid receptor mRNA expression in the nucleus accumbens of Wistar Kyoto rats by Dennis, Torry S., Beck, Kevin D., Cominski, Tara P., Bobzean, Samara A.M., Kuzhikandathil, Eldo V., Servatius, Richard J., Perrotti, Linda I.

“…•SD rats showed CPP for all morphine doses (0.5, 1.25, 2.5, 5, 7.5, or 10mg/kg).•WKY rats showed CPP for only mid-range (1.25, 2.5, and 5mg/kg) morphine…”
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Local field potentials in the ventral tegmental area during cocaine-induced locomotor activation: Measurements in freely moving rats by Harris Bozer, Amber L, Li, Ai-Ling, Sibi, Jiny E, Bobzean, Samara A.M, Peng, Yuan B, Perrotti, Linda I

“…Highlights • We recorded local field potential (LFP) activity in the ventral tegmental area (VTA). • Cocaine increased local field potentials in the VTA as…”
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Non-scanning fiber-optic near-infrared beam led to two-photon optogenetic stimulation in-vivo by Dhakal, Kamal R, Gu, Ling, Shivalingaiah, Shivaranjani, Dennis, Torry S, Morris-Bobzean, Samara A, Li, Ting, Perrotti, Linda I, Mohanty, Samarendra K

“…Stimulation of specific neurons expressing opsins in a targeted region to manipulate brain function has proved to be a powerful tool in neuroscience. However,…”
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Sex differences in the expression of morphine withdrawal symptoms and associated activity in the tail of the ventral tegmental area by Bobzean, Samara A.M., Kokane, Saurabh S., Butler, Brandon D., Perrotti, Linda I.

“…•We observed sex differences in the onset and severity of withdrawal symptoms.•Males withdrawal symptoms were more severe earlier in withdrawal than…”
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Histone Methyltransferase EZH2 Is Transcriptionally Induced by Estradiol as Well as Estrogenic Endocrine Disruptors Bisphenol-A and Diethylstilbestrol by Bhan, Arunoday, Hussain, Imran, Ansari, Khairul I., Bobzean, Samara A.M., Perrotti, Linda I., Mandal, Subhrangsu S.

“…Enhancer of Zeste homolog 2 (EZH2), a methyltransferase specific to histone 3 lysine 27, is a critical player in gene silencing and is overexpressed in breast…”
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Bisphenol-A induces expression of HOXC6, an estrogen-regulated homeobox-containing gene associated with breast cancer by Hussain, Imran, Bhan, Arunoday, Ansari, Khairul I., Deb, Paromita, Bobzean, Samara A.M., Perrotti, Linda I., Mandal, Subhrangsu S.

“…HOXC6 is a homeobox-containing gene associated with mammary gland development and is overexpressed in variety of cancers including breast and prostate cancers…”
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Acute estradiol treatment affects the expression of cocaine-induced conditioned place preference in ovariectomized female rats by Bobzean, Samara A.M, Dennis, Torry S, Perrotti, Linda I

“…Highlights • Examined the influence of an acute increase in estradiol on cocaine CPP. • OVX rats were given one treatment of estradiol 30 min prior to CPP…”
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Influence of sex on reinstatement of cocaine-conditioned place preference by Bobzean, Samara A. Morris, Dennis, Torry S, Addison, Brocke D, Perrotti, Linda I

“…Abstract To explore sex differences in reinstatement of conditioned place preference, we subjected intact male and female Long Evans rats to an extended…”
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Evaluating underlying neuronal activity associated with escape/avoidance behavior in response to noxious stimulation in adult rats by Uhelski, Megan L, Morris-Bobzean, Samara A, Dennis, Torry S, Perrotti, Linda I, Fuchs, Perry N

“…Abstract The place escape/avoidance paradigm (PEAP) is a behavioral test designed to quantify the level of unpleasantness evoked by painful stimuli by…”
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Assessing learned associations between conditioned cocaine reward and environmental stimuli in the Wistar Kyoto rat by Dennis, Torry S., Beck, Kevin D., Bobzean, Samara A. Morris, Dougall, Angela Liegey, Perrotti, Linda I.

“…Clinical studies demonstrate that anxiety disorders increase the risk of substance use disorder. However, few studies have directly assessed anxiety as a…”
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Sex differences in the neurobiology of drug addiction: The importance of sex in the etiology, presentation, and treatment of neurological disorders by BOBZEAN, Samara A. M, DENOBREGA, Aliza K, PERROTTI, Linda I

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Endocrine Disrupting Chemical, Bisphenol‐A, Induces Breast Cancer Associated Homeobox Containing Gene HOXB9 Expression in vitro and in vivo by Deb, Paromita, Bhan, Arunoday, Hussain, Imran, Ansari, Khairul I., Bobzean, Samara A., Saha, Debabrata, I Perrotti, Linda I., Mandal, Subhrangsu S.

“…Abstract only HOXB9 is a homeobox‐containing gene that plays key roles in mammary gland development and is associated with breast and other types of cancer. As…”
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Non-Scanning Fiber-Optic Near-Infrared Beam Led to Two-Photon Optogenetic Stimulation In-Vivo by Dhakal, Kamal R, Gu, Ling, Shivalingaiah, Shivaranjani, Dennis, Torry S, Morris-Bobzean, Samara A, Li, Ting, Perrotti, Linda I, Mohanty, Samarendra K

“…PLoS ONE 9(11): e111488 Stimulation of specific neurons expressing opsins in a targeted region to manipulate brain function has proved to be a powerful tool in…”
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