Search Results - "Bobryshev, Yuri V."

Macrophage‐mediated cholesterol handling in atherosclerosis by Chistiakov, Dimitry A., Bobryshev, Yuri V., Orekhov, Alexander N.

“…Formation of foam cells is a hallmark at the initial stages of atherosclerosis. Monocytes attracted by pro‐inflammatory stimuli attach to the inflamed vascular…”
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Endothelial Barrier and Its Abnormalities in Cardiovascular Disease by Chistiakov, Dimitry A, Orekhov, Alexander N, Bobryshev, Yuri V

“…Endothelial cells (ECs) form a unique barrier between the vascular lumen and the vascular wall. In addition, the endothelium is highly metabolically active. In…”
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The role of miR-126 in embryonic angiogenesis, adult vascular homeostasis, and vascular repair and its alterations in atherosclerotic disease by Chistiakov, Dimitry A, Orekhov, Alexander N, Bobryshev, Yuri V

“…Abstract Expression of microRNA (miR)-126 is enriched in endothelial cells (ECs) and endothelial progenitor cells (EPCs). MiR-126 is considered a master…”
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Mitochondrial Aging and Age-Related Dysfunction of Mitochondria by Orekhov, Alexander N., Sobenin, Igor A., Revin, Victor V., Bobryshev, Yuri V., Chistiakov, Dimitry A.

“…Age-related changes in mitochondria are associated with decline in mitochondrial function. With advanced age, mitochondrial DNA volume, integrity and…”
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Human miR-221/222 in Physiological and Atherosclerotic Vascular Remodeling by Bobryshev, Yuri V., Orekhov, Alexander N., Sobenin, Igor A., Chistiakov, Dimitry A.

“…A cluster of miR-221/222 is a key player in vascular biology through exhibiting its effects on vascular smooth muscle cells (VSMCs) and endothelial cells…”
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Changes in transcriptome of macrophages in atherosclerosis by Chistiakov, Dimitry A., Bobryshev, Yuri V., Orekhov, Alexander N.

“…Macrophages display significant phenotypic heterogeneity. Two growth factors, macrophage colony‐stimulating factor and chemokine (C‐X‐C motif) ligand 4, drive…”
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Cardiac Extracellular Vesicles in Normal and Infarcted Heart by Chistiakov, Dimitry A, Orekhov, Alexander N, Bobryshev, Yuri V

“…Heart is a complex assembly of many cell types constituting myocardium, endocardium and epicardium that intensively communicate to each other in order to…”
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LOX-1-Mediated Effects on Vascular Cells in Atherosclerosis by Chistiakov, Dimitry A., Orekhov, Alexander N., Bobryshev, Yuri V.

“…In healthy arteries, expression of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is almost undetectable. However, in proatherogenic…”
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Monocyte recruitment and foam cell formation in atherosclerosis by Bobryshev, Yuri V.

“…Atherosclerosis is a chronic immune-inflammatory disease in which the interactions of monocytes with activated endothelium are crucial events leading to…”
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Dendritic cells in atherosclerosis: current status of the problem and clinical relevance by BOBRYSHEV, Yuri V

“…Dendritic cells (DCs) are the most potent antigen-presenting cells. DCs were identified in arteries in 1995 and, since then, further knowledge has been gained…”
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Role of gut microbiota in the modulation of atherosclerosis-associated immune response by Chistiakov, Dmitry A, Bobryshev, Yuri V, Kozarov, Emil, Sobenin, Igor A, Orekhov, Alexander N

“…Inflammation and metabolic abnormalities are linked to each other. At present, pathogenic inflammatory response was recognized as a major player in metabolic…”
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Modified low density lipoprotein and lipoprotein-containing circulating immune complexes as diagnostic and prognostic biomarkers of atherosclerosis and type 1 diabetes macrovascular disease by Orekhov, Alexander N, Bobryshev, Yuri V, Sobenin, Igor A, Melnichenko, Alexandra A, Chistiakov, Dimitry A

“…In atherosclerosis; blood low-density lipoproteins (LDL) are subjected to multiple enzymatic and non-enzymatic modifications that increase their atherogenicity…”
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Peroxisome proliferator-activated receptor (PPAR) gamma in cardiovascular disorders and cardiovascular surgery by Ivanova, Ekaterina A., MSc, Parolari, Alessandro, MD, PhD, Myasoedova, Veronika, MD, PhD, Melnichenko, Alexandra A., PhD, DrSc, Bobryshev, Yuri V., PhD, DrSc, Orekhov, Alexander N., PhD, DrSc

“…Abstract Peroxisome proliferation-activated receptor gamma (PPARγ) is a nuclear receptor regulating transcription of several genes involved mainly in fatty…”
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Human immunodeficiency virus impairs reverse cholesterol transport from macrophages by Mujawar, Zahedi, Rose, Honor, Morrow, Matthew P, Pushkarsky, Tatiana, Dubrovsky, Larisa, Mukhamedova, Nigora, Fu, Ying, Dart, Anthony, Orenstein, Jan M, Bobryshev, Yuri V, Bukrinsky, Michael, Sviridov, Dmitri

“…Several steps of HIV-1 replication critically depend on cholesterol. HIV infection is associated with profound changes in lipid and lipoprotein metabolism and…”
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TRAIL-deficiency accelerates vascular calcification in atherosclerosis via modulation of RANKL by Di Bartolo, Belinda A, Cartland, Siân P, Harith, Hanis H, Bobryshev, Yuri V, Schoppet, Michael, Kavurma, Mary M

“…The osteoprotegerin (OPG) and receptor activator of nuclear factor-κB ligand (RANKL) cytokine system, not only controls bone homeostasis, but has been…”
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Novel Aberrations Uncovered in Barrett's Esophagus and Esophageal Adenocarcinoma Using Whole Transcriptome Sequencing by Maag, Jesper L V, Fisher, Oliver M, Levert-Mignon, Angelique, Kaczorowski, Dominik C, Thomas, Melissa L, Hussey, Damian J, Watson, David I, Wettstein, Antony, Bobryshev, Yuri V, Edwards, Melanie, Dinger, Marcel E, Lord, Reginald V

“…Esophageal adenocarcinoma (EAC) has one of the fastest increases in incidence of any cancer, along with poor five-year survival rates. Barrett's esophagus (BE)…”
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Australian clinical practice guidelines for the diagnosis and management of Barrett's esophagus and early esophageal adenocarcinoma by Whiteman, David C, Appleyard, Mark, Bahin, Farzan F, Bobryshev, Yuri V, Bourke, Michael J, Brown, Ian, Chung, Adrian, Clouston, Andrew, Dickins, Emma, Emery, Jon, Eslick, Guy D, Gordon, Louisa G, Grimpen, Florian, Hebbard, Geoff, Holliday, Laura, Hourigan, Luke F, Kendall, Bradley J, Lee, Eric YT, Levert-Mignon, Angelique, Lord, Reginald V, Lord, Sarah J, Maule, Derek, Moss, Alan, Norton, Ian, Olver, Ian, Pavey, Darren, Raftopoulos, Spiro, Rajendra, Shan, Schoeman, Mark, Singh, Rajvinder, Sitas, Freddy, Smithers, B Mark, Taylor, Andrew C, Thomas, Melissa L, Thomson, Iain, To, Henry, von Dincklage, Jutta, Vuletich, Christine, Watson, David I, Yusoff, Ian F

“…Barrett's esophagus (BE), a common condition, is the only known precursor to esophageal adenocarcinoma (EAC). There is uncertainty about the best way to manage…”
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Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance by Chistiakov, Dimitry A, Bobryshev, Yuri V, Kozarov, Emil, Sobenin, Igor A, Orekhov, Alexander N

“…The mucosal barriers are very sensitive to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to…”
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Epigenetic Alterations in DNA and Histone Modifications Caused by Depression and Antidepressant Drugs: Lessons from the Rodent Models by Chistiakov, Dimitry A, Bobryshev, Yuri V, Chekhonin, Vladimir P

“…Epigenetic modifications regulate chromatin folding and function. Epigenetic mechanisms regulate transcription mediating effects of various stimuli on gene…”
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Dendritic Cells in Colorectal Cancer and a Potential for their Use in Therapeutic Approaches by Chistiakov, Dimitry A, Orekhov, Alexander N, Bobryshev, Yuri V

“…Multiple pathogenic mechanisms contribute to the development of colorectal cancer. This tumor is characterized by high chemoresistance and low immunogenicity…”
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