Search Results - "Bobruskin, A. I."

Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma by Gelperina, S.E, Khalansky, A.S, Skidan, I.N, Smirnova, Z.S, Bobruskin, A.I, Severin, S.E, Turowski, B, Zanella, F.E, Kreuter, J

“…Polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles (NP) were shown to enable the transport of a number of drugs including the anti-tumour antibiotic…”
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Development and optimization of several stages of the technological process of filgrastim substance production by Kononova, N. V, Bobruskin, A. I, Kostromina, T. I, Melikhova, T. D, Vainson, A. A, Sveshnikova, E. V, Zinchenko, A. A, Demin, A. V, Martyanov, V. A, Shuster, A. M, Bairamashvili, D. I

“…Technology of industrial production of an active pharmaceutical substance (APS) of the recombinant human granulocyte colony-stimulating factor (rhG-CSF)…”
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Recombinant granulocyte colony-stimulating factor (filgrastim): Optimization of conjugation conditions with polyethylene glycol by Puchkov, I. A., Kononova, N. V., Bobruskin, A. I., Bairamashvili, D. I., Mart’yanov, V. A., Shuster, A. M.

“…With the purpose of creating an active prolonged-release pharmaceutical substance, modification of the recombinant human granulocyte colony-stimulating factor…”
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Recombinant granulocyte-colony stimulating factor (filgrastim): optimization of conditions of isolation and purification from inclusion body by Kononova, N V, Iakovlev, A V, Zhuravko, A M, Pankeev, N N, Minaev, S V, Bobruskin, A I, Mart'ianov, V A

“…We developed a unified process platform for two recombinant human GCSF medicines--one with the non-prolonged and the other with prolonged action. This unified…”
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Recombinant granulocyte-colony stimulating factor (filgrastim): optimization of conjugation with polyethylene glycol by Puchkov, I A, Kononova, N V, Bobruskin, A I, Bairamashvili, D I, Mart'ianov, V A, Shuster, A M

“…In order to create an active pharmaceutical substance of the drug with prolonged action the modification of recombinant human granulocyte colony-stimulating…”
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Solubilization Specificities Interferon beta-1b from Inclusion Bodies by Zhuravko, A S, Kononova, N V, Bobruskin, A I

“…A new solubilization method of recombinant interferon beta-1b (IFNβ-1b) from the inclusion bodies was developed. This method allows to extract the target…”
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Features of the solubilization of interferon beta-1B from inclusion bodies by Zhuravko, A. S., Kononova, N. V., Bobruskin, A. I.

“…A novel method for the solubilization of recombinant interferon beta-1b (IFNβ-1b) from inclusion bodies has been developed, which makes it possible to…”
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Recombinant granulocyte colony stimulating factor (filgrastim) of prolonged action: Optimization of conditions for extraction and purification from inclusion bodies by Kononova, N. V., Yakovlev, A. V., Zhuravko, A. M., Pankeev, N. N., Minaev, S. V., Bobruskin, A. I., Mart’yanov, V. A.

“…A unified technology platform for the production of two medical products with nonprolonged and prolonged action on the basis of the recombinant human…”
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Chemotherapy of glioblastoma in rats using doxorubicin‐loaded nanoparticles by Steiniger, Sebastian C.J., Kreuter, Jörg, Khalansky, Alexander S., Skidan, Igor N., Bobruskin, Alexey I., Smirnova, Zoya S., Severin, Sergey E., Uhl, Reiner, Kock, Martin, Geiger, Kathrin D., Gelperina, Svetlana E.

“…Glioblastomas belong to the most aggressive human cancers with short survival times. Due to the blood‐brain barrier, they are mostly inaccessible to…”
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Optimization of "Photosens" pharmakokinetics by biodegradable nanospheres by Skidan, I N, Bobruskin, A I, Guliaev, A E, Shalkharbaeva, S D, Severin, S E, Steinniger, S, Kreuter, J, Gel'perina, S E

“…The present study is dedicated to investigation of pharmacokinetics of the colloidal delivery system based on polybutylcyanoacrylate nanoparticles for the II…”
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