Search Results - "Bobrowski, Tesia"

ZINC Express: A Virtual Assistant for Purchasing Compounds Annotated in the ZINC Database by Bobrowski, Tesia M, Korn, Daniel R, Muratov, Eugene N, Tropsha, Alexander

“…Many laboratories working in the field of drug discovery use the ZINC database to identify and then acquire commercially available chemicals. However, finding…”
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Unambiguous detection of SARS-CoV-2 subgenomic mRNAs with single-cell RNA sequencing by Cohen, Phillip, DeGrace, Emma J, Danziger, Oded, Patel, Roosheel S, Barrall, Erika A, Bobrowski, Tesia, Kehrer, Thomas, Cupic, Anastija, Miorin, Lisa, García-Sastre, Adolfo, Rosenberg, Brad R

“…Single-cell RNA sequencing (scRNA-Seq) studies have provided critical insight into the pathogenesis of severe acute respiratory syndrome coronavirus 2…”
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Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 by Bobrowski, Tesia, Chen, Lu, Eastman, Richard T., Itkin, Zina, Shinn, Paul, Chen, Catherine Z., Guo, Hui, Zheng, Wei, Michael, Sam, Simeonov, Anton, Hall, Matthew D., Zakharov, Alexey V., Muratov, Eugene N.

“…Antiviral drug development for coronavirus disease 2019 (COVID-19) is occurring at an unprecedented pace, yet there are still limited therapeutic options for…”
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COVID-KOP: integrating emerging COVID-19 data with the ROBOKOP database by Korn, Daniel, Bobrowski, Tesia, Li, Michael, Kebede, Yaphet, Wang, Patrick, Owen, Phillips, Vaidya, Gaurav, Muratov, Eugene, Chirkova, Rada, Bizon, Chris, Tropsha, Alexander

“…Abstract Summary In response to the COVID-19 pandemic, we established COVID-KOP, a new knowledgebase integrating the existing Reasoning Over Biomedical Objects…”
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COVID-19 Knowledge Extractor (COKE): A Curated Repository of Drug–Target Associations Extracted from the CORD-19 Corpus of Scientific Publications on COVID-19 by Korn, Daniel, Pervitsky, Vera, Bobrowski, Tesia, Alves, Vinicius M, Schmitt, Charles, Bizon, Chris, Baker, Nancy, Chirkova, Rada, Cherkasov, Artem, Muratov, Eugene, Tropsha, Alexander

“…The COVID-19 pandemic has catalyzed a widespread effort to identify drug candidates and biological targets of relevance to SARS-COV-2 infection, which resulted…”
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Learning from history: do not flatten the curve of antiviral research by Bobrowski, Tesia, Melo-Filho, Cleber C., Korn, Daniel, Alves, Vinicius M., Popov, Konstantin I., Auerbach, Scott, Schmitt, Charles, Moorman, Nathaniel J., Muratov, Eugene N., Tropsha, Alexander

“…[Display omitted] •COVID-19 has caused the most rapid research response to a pandemic in recent history.•After epidemics end, less research is performed on the…”
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Conserved coronavirus proteins as targets of broad-spectrum antivirals by Melo-Filho, Cleber C., Bobrowski, Tesia, Martin, Holli-Joi, Sessions, Zoe, Popov, Konstantin I., Moorman, Nathaniel J., Baric, Ralph S., Muratov, Eugene N., Tropsha, Alexander

“…Coronaviruses are a class of single-stranded, positive-sense RNA viruses that have caused three major outbreaks over the past two decades: Middle East…”
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Praemonitus praemunitus: can we forecast and prepare for future viral disease outbreaks? by Sessions, Zoe, Bobrowski, Tesia, Martin, Holli-Joi, Beasley, Jon-Michael T, Kothari, Aneri, Phares, Trevor, Li, Michael, Alves, Vinicius M, Scotti, Marcus T, Moorman, Nathaniel J, Baric, Ralph, Tropsha, Alexander, Muratov, Eugene N

“…Abstract Understanding the origins of past and present viral epidemics is critical in preparing for future outbreaks. Many viruses, including SARS-CoV-2, have…”
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QSAR Modeling of SARS‐CoV Mpro Inhibitors Identifies Sufugolix, Cenicriviroc, Proglumetacin, and other Drugs as Candidates for Repurposing against SARS‐CoV‐2 by Alves, Vinicius M., Bobrowski, Tesia, Melo‐Filho, Cleber C., Korn, Daniel, Auerbach, Scott, Schmitt, Charles, Muratov, Eugene N., Tropsha, Alexander

“…The main protease (Mpro) of the SARS‐CoV‐2 has been proposed as one of the major drug targets for COVID‐19. We have identified the experimental data on the…”
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QSAR Modeling of SARS-CoV M pro Inhibitors Identifies Sufugolix, Cenicriviroc, Proglumetacin, and other Drugs as Candidates for Repurposing against SARS-CoV-2 by Alves, Vinicius M, Bobrowski, Tesia, Melo-Filho, Cleber C, Korn, Daniel, Auerbach, Scott, Schmitt, Charles, Muratov, Eugene N, Tropsha, Alexander

“…The main protease (M ) of the SARS-CoV-2 has been proposed as one of the major drug targets for COVID-19. We have identified the experimental data on the…”
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Allosteric Binders of ACE2 Are Promising Anti-SARS-CoV‑2 Agents by Hochuli, Joshua E., Jain, Sankalp, Melo-Filho, Cleber, Sessions, Zoe L., Bobrowski, Tesia, Choe, Jun, Zheng, Johnny, Eastman, Richard, Talley, Daniel C., Rai, Ganesha, Simeonov, Anton, Tropsha, Alexander, Muratov, Eugene N., Baljinnyam, Bolormaa, Zakharov, Alexey V.

“…The COVID-19 pandemic has had enormous health, economic, and social consequences. Vaccines have been successful in reducing rates of infection and…”
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