Search Results - "Boal, Frederic"

Apelin‐13 administration protects against ischaemia/reperfusion‐mediated apoptosis through the FoxO1 pathway in high‐fat diet‐induced obesity by Boal, Frederic, Timotin, Andrei, Roumegoux, Jessica, Alfarano, Chiara, Calise, Denis, Anesia, Rodica, Parini, Angelo, Valet, Philippe, Tronchere, Helene, Kunduzova, Oksana

“…Background and Purpose Apelin‐13, an endogenous ligand for the apelin (APJ) receptor, behaves as a potent modulator of metabolic and cardiovascular disorders…”
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Metformin Attenuates Postinfarction Myocardial Fibrosis and Inflammation in Mice by Loi, Halyna, Kramar, Solomiia, Laborde, Charlotte, Marsal, Dimitri, Pizzinat, Nathalie, Cussac, Daniel, Roncalli, Jerome, Boal, Frederic, Tronchere, Helene, Oleshchuk, Oleksandra, Korda, Mykhaylo, Kunduzova, Oksana

“…Diabetes is a major risk factor for the development of cardiovascular disease with a higher incidence of myocardial infarction. This study explores the role of…”
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Age-Related Shift in Cardiac and Metabolic Phenotyping Linked to Inflammatory Cytokines and Antioxidant Status in Mice by Kang, Ryeonshi, Laborde, Charlotte, Savchenko, Lesia, Swiader, Audrey, Pizzinat, Nathalie, Marsal, Dimitri, Sainte-Marie, Yannis, Boal, Frederic, Tronchere, Helene, Roncalli, Jerome, Kunduzova, Oksana

“…Age-related alterations in cardiac function, metabolic, inflammatory and antioxidant profiles are associated with an increased risk of cardiovascular mortality…”
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Metabolic, Apoptotic and Fibro-Inflammatory Profiles of the Heart Exposed to Environmental Electromagnetic Fields by Savchenko, Lesia, Martinelli, Ilenia, Marsal, Dimitri, Batkivska, Oksana, Zhdan, Vyacheslav, Kaidashev, Igor, Pizzinat, Nathalie, Boal, Frederic, Tronchere, Helene, Tao, Junwu, Kunduzova, Oksana

“…Environmental stress can disturb the integrative functioning of the cardiovascular system and trigger a number of adaptive and/or maladaptive cell responses…”
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Metformin Protects the Heart Against Hypertrophic and Apoptotic Remodeling After Myocardial Infarction by Loi, Halyna, Boal, Frederic, Tronchere, Helene, Cinato, Mathieu, Kramar, Solomiia, Oleshchuk, Oleksandra, Korda, Mykhaylo, Kunduzova, Oksana

“…Cardiovascular complications are the most prevalent cause of morbidity and mortality in diabetic patients. Metformin is currently the first-line blood…”
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In vitro and in vivo cardioprotective and metabolic efficacy of vitamin E TPGS/Apelin by Leme Goto, Patricia, Cinato, Mathieu, Merachli, Fadi, Vons, Bohdana, Jimenez, Tony, Marsal, Dimitri, Todua, Nika, Loi, Halyna, Santin, Yohan, Cassel, Stéphanie, Blanzat, Muriel, Tronchere, Helene, Dejugnat, Christophe, Kunduzova, Oksana, Boal, Frederic

“…Apelin and vitamin E have been proposed as signaling molecules, but their synergistic role is unknown. The aim of this work was to develop vitamin E…”
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Galanin promotes autophagy and alleviates apoptosis in the hypertrophied heart through FoxO1 pathway by Martinelli, Ilenia, Timotin, Andrei, Moreno-Corchado, Paula, Marsal, Dimitri, Kramar, Solomiia, Loy, Halina, Joffre, Carine, Boal, Frederic, Tronchere, Helene, Kunduzova, Oksana

“…Autophagy and apoptosis are powerful regulators of multiple facets of cellular metabolism and homeostasis. Here, we uncover that galanin, a pleiotropic…”
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Galanin Regulates Myocardial Mitochondrial ROS Homeostasis and Hypertrophic Remodeling Through GalR2 by Boal, Frederic, Cinato, Mathieu, Timotin, Andrei, Münzberg, Heike, Qualls-Creekmore, Emily, Kramar, Solomiia, Loi, Halyna, Roncalli, Jerome, Keita, Sokhna, Tronchere, Helene, Kunduzova, Oksana

“…The regulatory peptide galanin is broadly distributed in the central nervous systems and peripheral tissues where it modulates numerous physiological and…”
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Apelin regulates FoxO3 translocation to mediate cardioprotective responses to myocardial injury and obesity by Boal, Frederic, Roumegoux, Jessica, Alfarano, Chiara, Timotin, Andrei, Calise, Denis, Anesia, Rodica, Drougard, Anne, Knauf, Claude, Lagente, Christine, Roncalli, Jerome, Desmoulin, Franck, Tronchere, Helene, Valet, Philippe, Parini, Angelo, Kunduzova, Oksana

“…The increasing incidence of obesity accentuates the importance of identifying mechanisms and optimal therapeutic strategies for patients with heart failure…”
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Liposome Flotation Assays for Phosphoinositide-protein Interaction by Tronchere, Helene, Boal, Frederic

“…Phosphoinositides are rare membrane lipids involved in the control of the major cellular functions and signaling pathways. They are able to recruit specific…”
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TOM1 is a PI5P effector involved in the regulation of endosomal maturation by Boal, Frédéric, Mansour, Rana, Gayral, Marion, Saland, Estelle, Chicanne, Gaëtan, Xuereb, Jean-Marie, Marcellin, Marlène, Burlet-Schiltz, Odile, Sansonetti, Philippe J, Payrastre, Bernard, Tronchère, Hélène

“…Phosphoinositides represent a major class of lipids specifically involved in the organization of signaling cascades, maintenance of the identity of organelles…”
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PIKfyve-Dependent Phosphoinositide Dynamics in Megakaryocyte/Platelet Granule Integrity and Platelet Functions by Caux, Manuella, Mansour, Rana, Xuereb, Jean-Marie, Chicanne, Gaëtan, Viaud, Julien, Vauclard, Alicia, Boal, Frédéric, Payrastre, Bernard, Tronchère, Hélène, Severin, Sonia

“…Secretory granules are key elements for platelet functions. Their biogenesis and integrity are regulated by fine-tuned mechanisms that need to be fully…”
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Phosphatidylinositol 5-phosphate: A nuclear stress lipid and a tuner of membranes and cytoskeleton dynamics by Viaud, Julien, Boal, Frédéric, Tronchère, Hélène, Gaits-Iacovoni, Frédérique, Payrastre, Bernard

“…Phosphatidylinositol 5‐phosphate (PtdIns5P), the least characterized among the three phosphatidylinositol monophosphates, is emerging as a bioactive lipid…”
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Inhibition of PIKfyve prevents myocardial apoptosis and hypertrophy through activation of SIRT3 in obese mice by Tronchere, Helene, Cinato, Mathieu, Timotin, Andrei, Guitou, Laurie, Villedieu, Camille, Thibault, Helene, Baetz, Delphine, Payrastre, Bernard, Valet, Philippe, Parini, Angelo, Kunduzova, Oksana, Boal, Frederic

“…PIKfyve is an evolutionarily conserved lipid kinase that regulates pleiotropic cellular functions. Here, we identify PIKfyve as a key regulator of…”
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Specific functions of BIG1 and BIG2 in endomembrane organization by Boal, Frédéric, Stephens, David J

“…Transport of molecules from one subcellular compartment to another involves the recruitment of cytosolic coat protein complexes to a donor membrane to…”
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Retrospective Study of 573 Patients with Heart Failure Evaluated for Coronary Artery Disease at Toulouse University Center, France by Deney, Antoine, Nader, Vanessa, Matta, Anthony, Itier, Romain, Fournier, Pauline, Lairez, Olivier, Pizzinat, Nathalie, Carrié, Didier, Boal, Frédéric, Galinier, Michel, Kunduzova, Oksana, Azar, Rania, Roncalli, Jerome

“…BACKGROUND Heart failure (HF) most commonly occurs due to ischemic heart disease from stenotic coronary artery disease (CAD). HF is classified into 3 groups…”
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PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment by Boal, Frédéric, Puhar, Andrea, Xuereb, Jean-Marie, Kunduzova, Oksana, Sansonetti, Philippe J., Payrastre, Bernard, Tronchère, Hélène

“…Shigella flexneri, the pathogen responsible for bacillary dysentery, has evolved multiple strategies to control the inflammatory response. Here, we show that…”
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Differential protein profiling as a potential multi-marker approach for obese patients with heart failure: A retrospective study by Timotin, Andrei, Cinato, Mathieu, Boal, Frederic, Dejean, Sebastien, Anesia, Rodica, Arnaut, Oleg, Lagente, Christine, Roncalli, Jerome, Desmoulin, Franck, Tronchere, Helene, Kunduzova, Oksana

“…Identification of novel circulating biomarkers predicting death and major cardio-metabolic events in obese patients with heart failure (HF) remains a research…”
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charged prominence in the linker domain of the cysteine-string protein Cspα mediates its regulated interaction with the calcium sensor synaptotagmin 9 during exocytosis by Boal, Frédéric, Laguerre, Michel, Milochau, Alexandra, Lang, Jochen, Scotti, Pier A

“…The cochaperone cysteine-string protein (Csp) is located on vesicles and participates in the control of neurotransmission and hormone exocytosis. Csp contains…”
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The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network by Spooner, Robert A, Watson, Peter, Smith, Daniel C, Boal, Frédéric, Amessou, Mohammed, Johannes, Ludger, Clarkson, Guy J, Lord, J Michael, Stephens, David J, Roberts, Lynne M

“…The small-molecule inhibitor Exo2 {4-hydroxy-3-methoxy-(5,6,7,8-tetrahydrol[1]benzothieno[2,3-d]pyrimidin-4-yl)hydraz-one benzaldehyde} has been reported to…”
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