Search Results - "Boada, Yadira"
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Integrating mathematical modeling into synthetic biology education: a comprehensive approach through webinars and syllabus development
Published in Frontiers in education (Lausanne) (18-10-2024)“…Mathematical modeling is a fundamental aspect of synthetic biology, enabling precise design and analysis of biological systems. To enhance students'…”
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Extended Metabolic Biosensor Design for Dynamic Pathway Regulation of Cell Factories
Published in iScience (24-07-2020)“…Transcription factor-based biosensors naturally occur in metabolic pathways to maintain cell growth and to provide a robust response to environmental…”
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Gene Expression Space Shapes the Bioprocess Trade-Offs among Titer, Yield and Productivity
Published in Applied sciences (01-07-2021)“…Optimal gene expression is central for the development of both bacterial expression systems for heterologous protein production, and microbial cell factories…”
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PLATERO: A calibration protocol for plate reader green fluorescence measurements
Published in Frontiers in bioengineering and biotechnology (20-01-2023)“…One of the most common sources of information in Synthetic Biology is the data coming from plate reader fluorescence measurements. These experiments provide a…”
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Modeling and Optimization of a Molecular Biocontroller for the Regulation of Complex Metabolic Pathways
Published in Frontiers in molecular biosciences (29-03-2022)“…Achieving optimal production in microbial cell factories, robustness against changing intracellular and environmental perturbations requires the dynamic…”
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Modelling biochemical systems: from Mass Action Kinetics to Linear Noise Approximation
Published in Revista iberoamericana de automática e informática industrial (01-07-2015)“…In the last decade we have witnessed a growing application of engineering techniques to biology. Areas such as Systems Biology or, more recently, Synthetic…”
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Multi-Objective Optimization Tuning Framework for Kinetic Parameter Selection and Estimation
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Semi-mechanistic kinetic (i.e., dynamic) models based on first principles are particularly relevant in biology, as they can explain and predict functional…”
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Multiobjective Identification of a Feedback Synthetic Gene Circuit
Published in IEEE transactions on control systems technology (01-01-2020)“…Kinetic (i.e., dynamic) semimechanistic models based on the first principles are particularly important in systems and synthetic biology since they can explain…”
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Modelado de sistemas bioquímicos: De la Ley de Acción de Masas a la Aproximación Lineal del Ruido
Published in Revista iberoamericana de automática e informática industrial (01-07-2015)“…Durante la ultima década hemos vivido una creciente aplicación de técnicas propias de las ingenierías a la biología. Áreas como la Biología de Sistemas o, más…”
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Stochastic Differential Equations for Practical Simulation of Gene Circuits
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…The Chemical Langevin Equation approach allows simple stochastic simulation of gene circuits under many practical situations where the number of molecules of…”
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Advancements in synthetic biology-based bacterial cancer therapy: A modular design approach
Published in Critical reviews in oncology/hematology (01-10-2023)“…Synthetic biology aims to program living bacteria cells with artificial genetic circuits for user-defined functions, transforming them into powerful tools with…”
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Engineered Control of Genetic Variability Reveals Interplay among Quorum Sensing, Feedback Regulation, and Biochemical Noise
Published in ACS synthetic biology (20-10-2017)“…Stochastic fluctuations in gene expression trigger both beneficial and harmful consequences for cell behavior. Therefore, achieving a desired mean protein…”
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RBS and Promoter Strengths Determine the Cell-Growth-Dependent Protein Mass Fractions and Their Optimal Synthesis Rates
Published in ACS synthetic biology (17-12-2021)“…Models of gene expression considering host–circuit interactions are relevant for understanding both the strategies and associated trade-offs that cell…”
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Multi-objective optimization framework to obtain model-based guidelines for tuning biological synthetic devices: an adaptive network case
Published in BMC systems biology (11-03-2016)“…Model based design plays a fundamental role in synthetic biology. Exploiting modularity, i.e. using biological parts and interconnecting them to build new and…”
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Characterization of Gene Circuit Parts Based on Multiobjective Optimization by Using Standard Calibrated Measurements
Published in Chembiochem : a European journal of chemical biology (15-10-2019)“…Standardization and characterization of biological parts is necessary for the further development of bottom‐up synthetic biology. Herein, an easy‐to‐use…”
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Automated code evaluation of computer programming sessions with MATLAB Grader
Published in 2021 World Engineering Education Forum/Global Engineering Deans Council (WEEF/GEDC) (15-11-2021)“…Automatic grading of code and computational practices offers several beneficial practical and pedagogical advantages and is now possible using a variety of…”
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Conference Proceeding -
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Multicolor plate reader fluorescence calibration
Published in Synthetic biology (Oxford University Press) (02-02-2022)“…Abstract Plate readers are commonly used to measure cell growth and fluorescence, yet the utility and reproducibility of plate reader data is limited by the…”
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Control de Seguimiento de Trayectoria y Paletización de un Robot de Tres Grados de Libertad tipo SCARA (Selective Compliance Assembly Robot Arm)
Published in Revista Politécnica (Quito) (01-02-2014)“…El presente trabajo tiene por objeto el ensamblaje y control de los componentes de un robot SCARA de tres grados de libertad. El manipulador cuenta con tres…”
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