Search Results - "Böttcher, Claudia"

Ataxin‐3 consolidates the MDC1‐dependent DNA double‐strand break response by counteracting the SUMO‐targeted ubiquitin ligase RNF4 by Pfeiffer, Annika, Luijsterburg, Martijn S, Acs, Klara, Wiegant, Wouter W, Helfricht, Angela, Herzog, Laura K, Minoia, Melania, Böttcher, Claudia, Salomons, Florian A, van Attikum, Haico, Dantuma, Nico P

“…The SUMO‐targeted ubiquitin ligase RNF4 functions at the crossroads of the SUMO and ubiquitin systems. Here, we report that the deubiquitylation enzyme (DUB)…”
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The Machado–Joseph disease deubiquitylase ataxin‐3 interacts with LC3C/GABARAP and promotes autophagy by Herzog, Laura K., Kevei, Éva, Marchante, Ricardo, Böttcher, Claudia, Bindesbøll, Christian, Lystad, Alf Håkon, Pfeiffer, Annika, Gierisch, Maria E., Salomons, Florian A., Simonsen, Anne, Hoppe, Thorsten, Dantuma, Nico P.

“…The pathology of spinocerebellar ataxia type 3, also known as Machado‐Joseph disease, is triggered by aggregation of toxic ataxin‐3 (ATXN3) variants containing…”
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Selective Accumulation of Aggregation-Prone Proteasome Substrates in Response to Proteotoxic Stress by Salomons, Florian A., Menéndez-Benito, Victoria, Böttcher, Claudia, McCray, Brett A., Taylor, J. Paul, Dantuma, Nico P.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Accumulation of Ubiquitin Conjugates in a Polyglutamine Disease Model Occurs without Global Ubiquitin/Proteasome System Impairment by Maynard, Christa J., Böttcher, Claudia, Ortega, Zaira, Smith, Ruben, Florea, Bogdan I., Díaz-Hernández, Miguel, Brundin, Patrik, Overkleeft, Hermen S., Li, Jia-Yi, Lucas, Jose J., Dantuma, Nico P., Zoghbi, Huda Y.

“…Aggregation-prone proteins have been suggested to overwhelm and impair the ubiquitin/proteasome system (UPS) in polyglutamine (polyQ) disorders, such as…”
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Alzheimer's Disease-Associated Ubiquilin-1 Regulates Presenilin-1 Accumulation and Aggresome Formation by Viswanathan, Jayashree, Haapasalo, Annakaisa, Böttcher, Claudia, Miettinen, Riitta, Kurkinen, Kaisa M.A, Lu, Alice, Thomas, Anne, Maynard, Christa J, Romano, Donna, Hyman, Bradley T, Berezovska, Oksana, Bertram, Lars, Soininen, Hilkka, Dantuma, Nico P, Tanzi, Rudolph E, Hiltunen, Mikko

“…The Alzheimer's disease (AD)-associated ubiquilin-1 regulates proteasomal degradation of proteins, including presenilin (PS). PS-dependent γ-secretase…”
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Mutant p62/SQSTM1 UBA domains linked to Paget’s disease of bone differ in their abilities to function as stabilization signals by Heinen, Christian, Garner, Thomas P., Long, Jed, Böttcher, Claudia, Ralston, Stuart H., Cavey, James R., Searle, Mark S., Layfield, Robert, Dantuma, Nico P.

“…We show that the ubiquitin-associated domain (UBA) of human p62/sequestosome-1 (SQSTM1) can delay degradation of proteasome substrates in yeast. Taking…”
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Flower perianth: first observations on a novel diet item for the ponerine ant Odontomachus chelifer (Latreille) by Bieber, Ana Gabriela Delgado, Pereira, Eduardo Roberto, Bottcher, Claudia

“…Ants are known to feed on a variety of plant resources. Nevertheless, there are very few reports in the literature on ants using flower parts. Here, we…”
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Early vs late histological confirmation of coeliac disease in children with new-onset type 1 diabetes by Kamrath, Clemens, Tittel, Sascha R., Dunstheimer, Desiree, Fröhlich-Reiterer, Elke, Freff, Markus, Böttcher, Claudia, Scheffler, Nadine, Lenze, Stefanie, Gericke, Elke, Thiele, Susanne, Holl, Reinhard W.

“…Aim Screening for coeliac disease in asymptomatic children with new-onset type 1 diabetes is controversial. The aim of this study was to analyse whether the…”
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Reversible severe glycogenic hepatopathy in type 1 diabetes by de Laffolie, Jan, Kamrath, Clemens, Burchert, Diana, Böttcher, Claudia, Wudy, Stefan Alexander, Zimmer, Klaus-Peter

“…Summary Case presentation We report a case of severe glycogenic hepatopathy in a 17-year-old boy with poorly controlled type 1 diabetes. On presentation, major…”
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Einführung by Böttcher, Claudia, Kötzing, Andreas

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Editorial by Böttcher, Claudia, Kötzing, Andreas

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Einführung by Claudia Böttcher, Andreas Kötzing

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Family System Dynamics and Type 1 Diabetic Glycemic Variability: A Vector-Auto-Regressive Model by Günther, Moritz Philipp, Winker, Peter, Böttcher, Claudia, Brosig, Burkhard

“…Statistical approaches rooted in econometric methodology, so far foreign to the psychiatric and psychological realms have provided exciting and substantial new…”
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Ataxin‐3 consolidates the MDC 1‐dependent DNA double‐strand break response by counteracting the SUMO ‐targeted ubiquitin ligase RNF 4 by Pfeiffer, Annika, Luijsterburg, Martijn S, Acs, Klara, Wiegant, Wouter W, Helfricht, Angela, Herzog, Laura K, Minoia, Melania, Böttcher, Claudia, Salomons, Florian A, van Attikum, Haico, Dantuma, Nico P

“…The SUMO ‐targeted ubiquitin ligase RNF 4 functions at the crossroads of the SUMO and ubiquitin systems. Here, we report that the deubiquitylation enzyme ( DUB…”
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P2‐281: Alzheimer's disease‐associated ubiquilin‐1 regulates presenilin‐1 accumulation and aggresome formation by Haapasalo, Annakaisa, Viswanathan, Jayashree, Böttcher, Claudia, Miettinen, Riitta, Kurkinen, Kaisa, Maynard, Christa J., Lu, Alice, Bertram, Lars, Soininen, Hilkka, Tanzi, Rudolph E., Dantuma, Nico P., Hiltunen, Mikko

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Sjl2p is specifically involved in early steps of endocytosis intimately linked to actin dynamics via the Ark1p/Prk1p kinases by Böttcher, Claudia, Wicky, Sidonie, Schwarz, Heinz, Singer-Krüger, Birgit

“…Sjl2p is one of three yeast phosphoinositide 5′-phosphatases that belong to the conserved family of synaptojanins. Here, we show that Sjl2p is specifically…”
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Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation by Haapasalo, Annakaisa, Viswanathan, Jayashree, Böttcher, Claudia, Miettinen, Riitta, Kurkinen, Kaisa, Maynard, Christa J, Lu, Alice, Bertram, Lars, Soininen, Hilkka, Tanzi, Rudolph E, Dantuma, Nico P, Hiltunen, Mikko

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Consumption of lipid-rich seed arils improves larval development in a Neotropical primarily carnivorous ant, Odontomachus chelifer (Ponerinae) by Bottcher, Claudia, Oliveira, Paulo S.

“…Odontomachus chelifer ants collect fallen arillate seeds of Cabralea canjerana (Meliaceae), a bird-dispersed tree of the Atlantic rain forest. In the nest the…”
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Asymmetric effects of changes in the habitat‐forming algae Sargassum on different associated mobile faunas along São Paulo coast, Brazil by Leite, Fosca P. P., Bottcher, Claudia, Lewinsohn, Ilana D. A., Siqueira, Silvana G. L., Mansur, Karine F. R., Longo, Pedro A. S., Vieira, Edson A.

“…Macroalgae constitute an important habitat for several marine invertebrates, and their biomass and structural complexity modulates the abundance and diversity…”
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Extrafloral nectaries as a deterrent mechanism against seed predators in the chemically protected weed Crotalaria pallida (Leguminosae) by GUIMARÃES, PAULO R. JR, RAIMUNDO, RAFAEL L.G, BOTTCHER, CLÁUDIA, SILVA, ROGÉRIO R, TRIGO, JOSÉ R

“…In several plants, extrafloral nectaries (EFN) are located close to the reproductive structures, suggesting that ants may act as a defence against specialized…”
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