Search Results - "Boñaga, Llorente V.R."

When the Pauson–Khand and Pauson–Khand type reactions go awry: a plethora of unexpected results by Boñaga, Llorente V.R., Krafft, Marie E.

“…Covering the period from 1971 to mid-2004, this review attempts to present, in a comprehensive organization, common side reactions and unconventional results…”
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Synthesis of Macrocycles via Cobalt-Mediated [2 + 2 + 2] Cycloadditions by Boñaga, Llorente V. R, Zhang, Han-Cheng, Moretto, Alessandro F, Ye, Hong, Gauthier, Diane A, Li, Jian, Leo, Gregory C, Maryanoff, Bruce E

“…We investigated the formation of macrocycles from α,ω-diynes in cobalt-mediated co-cyclotrimerization reactions. Long-chain α,ω-diynes underwent metal-mediated…”
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Novel bis(indolyl)maleimide pyridinophanes that are potent, selective inhibitors of glycogen synthase kinase-3 by Zhang, Han-Cheng, Boñaga, Llorente V.R., Ye, Hong, Derian, Claudia K., Damiano, Bruce P., Maryanoff, Bruce E.

“…Bis(indolyl)maleimide pyridinophanes (‘multiheterophane’), from cobalt-mediated[2+2+2] cycloaddition, were found to be potent, selective inhibitors of GSK-3β…”
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Cobalt-mediated cyclotrimerisation of bis-alkynes and cyanamides by Boñaga, Llorente V R, Zhang, Han-Cheng, Maryanoff, Bruce E

“…CpCo(CO)2-mediated cyclotrimerisation of bis-alkynes and cyanamides provides multisubstituted 2-aminopyridines, including macrocyclic products, such as 22 (50%…”
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Dienes from the thermolysis of dicobalthexacarbonyl-complexed enynes: Mechanistic insight by Krafft, Marie E, Wilson, Anne M, Dasse, Oliver A, Bonaga, Llorente V.R, Cheung, Y.Y, Fu, Zice, Shao, Bin, Scott, Ian L

“…Thermolysis of the hexacarbonyldicobalt complex of 1,6- or 1,7-enynes yields monocyclic 1,3-dienes. Deuterium labeling studies rule out an α-elimination as the…”
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Cobalt-Mediated Macrocyclizations. Facile Synthesis of 2-Oxo Pyridinophanes via [2 + 2 + 2] Cycloaddition of α,ω-Diynes and Isocyanates by Boñaga, Llorente V. R, Zhang, Han-Cheng, Gauthier, Diane A, Reddy, Indrasena, Maryanoff, Bruce E

“…Cobalt-mediated [2 + 2 + 2] cycloaddition of α,ω-diynes and isocyanates provides a direct approach to macrocyclic 2-oxopyridinophanes. This macrocyclization…”
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Aqueous-phase, thermal Pauson–Khand reactions in the presence of surfactants by Krafft, Marie E., Wright, James A., Boñaga, Llorente V.R.

“…Efficient stoichiometric Pauson–Khand reactions were realized in water as the only solvent, and in the presence of surfactants as additives. Use of the…”
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A Sterically-Encumbered, C2-Symmetric Chiral Acetal for Enhanced Asymmetric Induction in the Pauson−Khand Reaction by KRAFFT, Marie E., BOñAGA, Llorente V. R., FELTS, Andrew S., HIROSAWA, Chitaru, KERRIGAN, Sean

“…High levels of diastereoselection were achieved in the PKR of 1,6- and 1,7-cyclopropylidenynes bearing a bulky propargylic C(2)-symmetric acetal…”
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Pauson–Khand reactions in water by Krafft, Marie E, Wright, James A, Boñaga, Llorente VR

“…We have investigated the cobalt mediated Pauson–Khand (PK) reaction in water. In the presence of detergents and surfactants, Co 2 (CO) 8 and Co 4 (CO) 12 are…”
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