Two Fatty Liver Conditions Masquerading as Autoimmune Hepatitis

Two Fatty Liver Conditions Masquerading as Autoimmune Hepatitis

Acute fatty liver of pregnancy (AFLP) is a rare obstetric condition that classically presents in the third trimester or early postpartum period and can lead to liver failure and death. Only six second trimester AFLP cases have been reported in the English literature. We present the earliest case of...

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Bibliographic Details
Published in:Case reports in hepatology Vol. 2021; pp. 1 - 5
Main Authors: Hendrie, Jonathan David, Blumer, Mary Crouse, Fenton, Hubert Henry, Abrams, Gary Anthony
Format: Journal Article
Language:English
Published: New York Hindawi 09-03-2021
Hindawi Limited
Subjects:
Abdomen
Antibodies
Antigens
Biopsy
Blood
Case Report
Case reports
Creatinine
Fatty acids
Fetuses
Gallbladder diseases
Gestational age
Hepatitis
Hypoglycemia
Laboratories
Liver transplants
Metabolism
Metabolites
Mortality
Pathophysiology
Patients
Postpartum period
Pregnancy
Ultrasonic imaging
Vomiting
Womens health
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Summary:Acute fatty liver of pregnancy (AFLP) is a rare obstetric condition that classically presents in the third trimester or early postpartum period and can lead to liver failure and death. Only six second trimester AFLP cases have been reported in the English literature. We present the earliest case of AFLP at 15 weeks of gestation confounded by a high titer anti-nuclear antibody (ANA >1 : 1280) and concern for autoimmune hepatitis. Our patient had intrauterine fetal demise with prompt dilation and evacuation. Sepsis and multisystem organ failure ensued, and she was transferred to a liver transplant center where she expired without further intervention.
Bibliography:Academic Editor: Haruki Komatsu
ISSN:2090-6587
2090-6595
DOI:10.1155/2021/8820350