Search Results - "Blumenthal, Jonathan D."

Sex-chromosome dosage effects on gene expression in humans by Raznahan, Armin, Parikshak, Neelroop N., Chandran, Vijay, Blumenthal, Jonathan D., Clasen, Liv S., Alexander-Bloch, Aaron F., Zinn, Andrew R., Wangsa, Danny, Wise, Jasen, Murphy, Declan G. M., Bolton, Patrick F., Ried, Thomas, Ross, Judith, Giedd, Jay N., Geschwind, Daniel H.

“…A fundamental question in the biology of sex differences has eluded direct study in humans: How does sex-chromosome dosage (SCD) shape genome function? To…”
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Normative brain size variation and brain shape diversity in humans by Reardon, P K, Seidlitz, Jakob, Vandekar, Simon, Liu, Siyuan, Patel, Raihaan, Park, Min Tae M, Alexander-Bloch, Aaron, Clasen, Liv S, Blumenthal, Jonathan D, Lalonde, Francois M, Giedd, Jay N, Gur, Ruben C, Gur, Raquel E, Lerch, Jason P, Chakravarty, M Mallar, Satterthwaite, Theodore D, Shinohara, Russell T, Raznahan, Armin

“…Brain size variation over primate evolution and human development is associated with shifts in the proportions of different brain regions. Individual brain…”
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Sexual dimorphism of brain developmental trajectories during childhood and adolescence by Lenroot, Rhoshel K., Gogtay, Nitin, Greenstein, Deanna K., Wells, Elizabeth Molloy, Wallace, Gregory L., Clasen, Liv S., Blumenthal, Jonathan D., Lerch, Jason, Zijdenbos, Alex P., Evans, Alan C., Thompson, Paul M., Giedd, Jay N.

“…Human total brain size is consistently reported to be ∼ 8–10% larger in males, although consensus on regionally specific differences is weak. Here, in the…”
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Sex-biased trajectories of amygdalo-hippocampal morphology change over human development by Fish, Ari M., Nadig, Ajay, Seidlitz, Jakob, Reardon, Paul K., Mankiw, Catherine, McDermott, Cassidy L., Blumenthal, Jonathan D., Clasen, Liv S., Lalonde, Francois, Lerch, Jason P., Chakravarty, M. Mallar, Shinohara, Russell T., Raznahan, Armin

“…The amygdala and hippocampus are two adjacent allocortical structures implicated in sex-biased and developmentally-emergent psychopathology. However, the…”
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Deep phenotypic analysis of psychiatric features in genetically defined cohorts: application to XYY syndrome by Raznahan, Armin, Rau, Srishti, Schaffer, Luke, Liu, Siyuan, Fish, Ari M, Mankiw, Catherine, Xenophontos, Anastasia, Clasen, Liv S, Joseph, Lisa, Thurm, Audrey, Blumenthal, Jonathan D, Bassett, Dani S, Torres, Erin N

“…Recurrent gene dosage disorders impart substantial risk for psychopathology. Yet, understanding that risk is hampered by complex presentations that challenge…”
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Integrative structural, functional, and transcriptomic analyses of sex-biased brain organization in humans by Liu, Siyuan, Seidlitz, Jakob, Blumenthal, Jonathan D., Clasen, Liv S., Raznahan, Armin

“…Humans display reproducible sex differences in cognition and behavior, which may partly reflect intrinsic sex differences in regional brain organization…”
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Sex-specific associations between subcortical morphometry in childhood and adult alcohol consumption: A 17-year follow-up study by Mankiw, Catherine, Whitman, Ethan T., Torres, Erin, Lalonde, François, Clasen, Liv S., Blumenthal, Jonathan D., Chakravarty, M. Mallar, Raznahan, Armin

“…•17-Year follow up linking pediatric brain anatomy with adult drinking.•Female-specific relationships between subcortical anatomy and adult drinking.•Effects…”
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Longitudinally Mapping Childhood Socioeconomic Status Associations with Cortical and Subcortical Morphology by McDermott, Cassidy L, Seidlitz, Jakob, Nadig, Ajay, Liu, Siyuan, Clasen, Liv S, Blumenthal, Jonathan D, Reardon, Paul Kirkpatrick, Lalonde, François, Greenstein, Deanna, Patel, Raihaan, Chakravarty, M Mallar, Lerch, Jason P, Raznahan, Armin

“…Childhood socioeconomic status (SES) impacts cognitive development and mental health, but its association with human structural brain development is not yet…”
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Motion Artifact in Magnetic Resonance Imaging: Implications for Automated Analysis by Blumenthal, Jonathan D., Zijdenbos, Alex, Molloy, Elizabeth, Giedd, Jay N.

“…Automated measures of cerebral magnetic resonance images (MRI) often provide greater speed and reliability compared to manual techniques but can be…”
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Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders by Seidlitz, Jakob, Nadig, Ajay, Liu, Siyuan, Bethlehem, Richard A. I., Vértes, Petra E., Morgan, Sarah E., Váša, František, Romero-Garcia, Rafael, Lalonde, François M., Clasen, Liv S., Blumenthal, Jonathan D., Paquola, Casey, Bernhardt, Boris, Wagstyl, Konrad, Polioudakis, Damon, de la Torre-Ubieta, Luis, Geschwind, Daniel H., Han, Joan C., Lee, Nancy R., Murphy, Declan G., Bullmore, Edward T., Raznahan, Armin

“…Neurodevelopmental disorders have a heritable component and are associated with region specific alterations in brain anatomy. However, it is unclear how…”
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Brain and behavior in 48, XXYY syndrome by Hanley, Alli P, Blumenthal, Jonathan D, Lee, Nancy Raitano, Baker, Eva H, Clasen, Liv S, Giedd, Jay N

“…The phenotype of 48, XXYY syndrome (referred to as XXYY) is associated with characteristic but variable developmental, cognitive, behavioral and physical…”
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Globally Divergent but Locally Convergent X- and Y-Chromosome Influences on Cortical Development by Raznahan, Armin, Lee, Nancy Raitano, Greenstein, Deanna, Wallace, Gregory L, Blumenthal, Jonathan D, Clasen, Liv S, Giedd, Jay N

“…Owing to their unique evolutionary history, modern mammalian X- and Y-chromosomes have highly divergent gene contents counterbalanced by regulatory features,…”
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Brain morphological abnormalities in 49,XXXXY syndrome: A pediatric magnetic resonance imaging study by Blumenthal, Jonathan D, Baker, Eva H, Lee, Nancy Raitano, Wade, Benjamin, Clasen, Liv S, Lenroot, Rhoshel K, Giedd, Jay N

“…As a group, people with the sex chromosome aneuploidy 49,XXXXY have characteristic physical and cognitive/behavioral tendencies, although there is high…”
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Allometric Analysis Detects Brain Size-Independent Effects of Sex and Sex Chromosome Complement on Human Cerebellar Organization by Mankiw, Catherine, Park, Min Tae M, Reardon, P K, Fish, Ari M, Clasen, Liv S, Greenstein, Deanna, Giedd, Jay N, Blumenthal, Jonathan D, Lerch, Jason P, Chakravarty, M Mallar, Raznahan, Armin

“…The cerebellum is a large hindbrain structure that is increasingly recognized for its contribution to diverse domains of cognitive and affective processing in…”
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Sex Chromosome Dosage Effects on White Matter Structure in the Human Brain by Warling, Allysa, Yavi, Mani, Clasen, Liv S, Blumenthal, Jonathan D, Lalonde, François M, Raznahan, Armin, Liu, Siyuan

“…Abstract Sex chromosome aneuploidies, a group of neurogenetic conditions characterized by aberrant sex chromosome dosage (SCD), are associated with increased…”
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Morphological integration of the human brain across adolescence and adulthood by Nadig, Ajay, Seidlitz, Jakob, McDermott, Cassidy L., Liu, Siyuan, Bethlehem, Richard, Moore, Tyler M., Mallard, Travis T., Clasen, Liv S., Blumenthal, Jonathan D., Lalonde, François, Gur, Ruben C., Gur, Raquel E., Bullmore, Edward T., Satterthwaite, Theodore D., Raznahan, Armin

“…Brain structural covariance norms capture the coordination of neurodevelopmental programs between different brain regions. We develop and apply anatomical…”
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Influences of Brain Size, Sex, and Sex Chromosome Complement on the Architecture of Human Cortical Folding by Fish, Ari M, Cachia, Arnaud, Fischer, Clara, Mankiw, Catherine, Reardon, P K, Clasen, Liv S, Blumenthal, Jonathan D, Greenstein, Deanna, Giedd, Jay N, Mangin, Jean-François, Raznahan, Armin

“…Gyrification is a fundamental property of the human cortex that is increasingly studied by basic and clinical neuroscience. However, it remains unclear if and…”
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Altered Sex Chromosome Dosage Induces Coordinated Shifts in Cortical Anatomy and Anatomical Covariance by Xenophontos, Anastasia, Seidlitz, Jakob, Liu, Siyuan, Clasen, Liv S, Blumenthal, Jonathan D, Giedd, Jay N, Alexander-Bloch, Aaron, Raznahan, Armin

“…Abstract Sex chromosome dosage (SCD) variation increases risk for neuropsychiatric impairment, which may reflect direct SCD effects on brain organization…”
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Resting-State Functional Connectivity and Psychopathology in Klinefelter Syndrome (47, XXY) by Whitman, Ethan T, Liu, Siyuan, Torres, Erin, Warling, Allysa, Wilson, Kathleen, Nadig, Ajay, McDermott, Cassidy, Clasen, Liv S, Blumenthal, Jonathan D, Lalonde, François M, Gotts, Stephen J, Martin, Alex, Raznahan, Armin

“…Abstract Klinefelter syndrome (47, XXY; henceforth: XXY syndrome) is a high-impact but poorly understood genetic risk factor for neuropsychiatric impairment…”
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Sex chromosome aneuploidy alters the relationship between neuroanatomy and cognition by Warling, Allysa, Liu, Siyuan, Wilson, Kathleen, Whitman, Ethan, Lalonde, François M., Clasen, Liv S., Blumenthal, Jonathan D., Raznahan, Armin

“…Sex chromosome aneuploidy (SCA) increases the risk for cognitive deficits, and confers changes in regional cortical thickness (CT) and surface area (SA)…”
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