Search Results - "Blume, E"

Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona by Blume, John E., Manning, William C., Troiano, Gregory, Hornburg, Daniel, Figa, Michael, Hesterberg, Lyndal, Platt, Theodore L., Zhao, Xiaoyan, Cuaresma, Rea A., Everley, Patrick A., Ko, Marwin, Liou, Hope, Mahoney, Max, Ferdosi, Shadi, Elgierari, Eltaher M., Stolarczyk, Craig, Tangeysh, Behzad, Xia, Hongwei, Benz, Ryan, Siddiqui, Asim, Carr, Steven A., Ma, Philip, Langer, Robert, Farias, Vivek, Farokhzad, Omid C.

“…Large-scale, unbiased proteomics studies are constrained by the complexity of the plasma proteome. Here we report a highly parallel protein quantitation…”
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Market size and innovation: Effects of Medicare Part D on pharmaceutical research and development by Blume-Kohout, Margaret E., Sood, Neeraj

“…Recent evidence suggests that Medicare Part D increased prescription drug use among seniors, and increased pharmaceutical firms' revenues from sales. Previous…”
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Functionally distinct BMP1 isoforms show an opposite pattern of abundance in plasma from non-small cell lung cancer subjects and controls by Donovan, Margaret K R, Huang, Yingxiang, Blume, John E, Wang, Jian, Hornburg, Daniel, Ferdosi, Shadi, Mohtashemi, Iman, Kim, Sangtae, Ko, Marwin, Benz, Ryan W, Platt, Theodore L, Batzoglou, Serafim, Diaz, Luis A, Farokhzad, Omid C, Siddiqui, Asim

“…Advancements in deep plasma proteomics are enabling high-resolution measurement of plasma proteoforms, which may reveal a rich source of novel biomarkers…”
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Incentivizing STEM participation: Evidence from the SMART Grant Program by Blume‐Kohout, Margaret E., Scott, Jacob P.

“…The U.S. National Science and Mathematics Access to Retain Talent (SMART) Grant program provided up to $8000 to high‐achieving, low‐income undergraduates…”
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Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation by Salomonis, Nathan, Schlieve, Christopher R, Pereira, Laura, Wahlquist, Christine, Colas, Alexandre, Zambon, Alexander C, Vranizan, Karen, Spindler, Matthew J, Pico, Alexander R, Cline, Melissa S, Clark, Tyson A, Williams, Alan, Blume, John E, Samal, Eva, Mercola, Mark, Merrill, Bradley J, Conklin, Bruce R

“…Two major goals of regenerative medicine are to reproducibly transform adult somatic cells into a pluripotent state and to control their differentiation into…”
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Cleavage of annexin A1 by ADAM10 during secondary necrosis generates a monocytic "find-me" signal by Blume, Karin E, Soeroes, Szabolcs, Keppeler, Hildegard, Stevanovic, Stefan, Kretschmer, Dorothee, Rautenberg, Maren, Wesselborg, Sebastian, Lauber, Kirsten

“…Annexin A1 is an intracellular calcium/phospholipid-binding protein that is involved in membrane organization and the regulation of the immune system. It has…”
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Pediatric heart transplantation across a positive crossmatch: First year results from the CTOTC‐04 multi‐institutional study by Webber, S., Zeevi, A., Mason, K., Addonizio, L., Blume, E., Dipchand, A., Shaddy, R., Feingold, B., Canter, C., Hsu, D., Mahle, W., Armstrong, B., Morrison, Y., Ikle, D., Diop, H., Odim, J.

“…Sensitization is common in pediatric heart transplant candidates and waitlist mortality is high. Transplantation across a positive crossmatch may reduce wait…”
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Discovery of tissue-specific exons using comprehensive human exon microarrays by Clark, Tyson A, Schweitzer, Anthony C, Chen, Tina X, Staples, Michelle K, Lu, Gang, Wang, Hui, Williams, Alan, Blume, John E

“…Higher eukaryotes express a diverse population of messenger RNAs generated by alternative splicing. Large-scale methods for monitoring gene expression must…”
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Outcome of listing for cardiac transplantation for failed fontan : A multi-institutional study by BERNSTEIN, D, NAFTEL, D, CHIN, C, ADDONIZIO, L. J, GAMBERG, P, BLUME, E. D, HSU, D, CANTER, C. E, KIRKLIN, J. K, MORROW, W. R

“…The Fontan procedure is a successful palliation for children with single-ventricle physiology; however, many will eventually require heart transplantation. The…”
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Identification of Genetic Variants Contributing to Cisplatin-Induced Cytotoxicity by Use of a Genomewide Approach by Huang, R. Stephanie, Duan, Shiwei, Shukla, Sunita J., Kistner, Emily O., Clark, Tyson A., Chen, Tina X., Schweitzer, Anthony C., Blume, John E., Dolan, M. Eileen

“…Cisplatin, a platinating agent commonly used to treat several cancers, is associated with nephrotoxicity, neurotoxicity, and ototoxicity, which has hindered…”
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A large-scale and robust dynamic MRM study of colorectal cancer biomarkers by You, Jia, Kao, Athit, Dillon, Roslyn, Croner, Lisa J., Benz, Ryan, Blume, John E., Wilcox, Bruce

“…Over the past 20 years, mass spectrometry (MS) has emerged as a dynamic tool for proteomics biomarker discovery. However, published MS biomarker candidates…”
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Incidence, characterization, and impact of newly detected donor‐specific anti‐HLA antibody in the first year after pediatric heart transplantation: A report from the CTOTC‐04 study by Dipchand, A. I., Webber, S., Mason, K., Feingold, B., Bentlejewski, C., Mahle, W. T., Shaddy, R., Canter, C., Blume, E. D., Lamour, J., Zuckerman, W., Diop, H., Morrison, Y., Armstrong, B., Ikle, D., Odim, J., Zeevi, A.

“…Data on the clinical importance of newly detected donor‐specific anti‐HLA antibodies (ndDSAs) after pediatric heart transplantation are lacking despite…”
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Cell Surface Externalization of Annexin A1 as a Failsafe Mechanism Preventing Inflammatory Responses during Secondary Necrosis by Blume, Karin E, Soeroes, Szabolcs, Waibel, Michaela, Keppeler, Hildegard, Wesselborg, Sebastian, Herrmann, Martin, Schulze-Osthoff, Klaus, Lauber, Kirsten

“…The engulfment of apoptotic cells is of crucial importance for tissue homeostasis in multicellular organisms. A failure of this process results in secondary…”
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A Genome-Wide Approach to Identify Genetic Variants That Contribute to Etoposide-Induced Cytotoxicity by Huang, R. Stephanie, Duan, Shiwei, Bleibel, Wasim K., Kistner, Emily O., Zhang, Wei, Clark, Tyson A., Chen, Tina X., Schweitzer, Anthony C., Blume, John E., Cox, Nancy J., Dolan, M. Eileen

“…Large interindividual variance has been observed in sensitivity to drugs. To comprehensively decipher the genetic contribution to these variations in drug…”
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Genetic Architecture of Transcript-Level Variation in Humans by Duan, Shiwei, Huang, R. Stephanie, Zhang, Wei, Bleibel, Wasim K., Roe, Cheryl A., Clark, Tyson A., Chen, Tina X., Schweitzer, Anthony C., Blume, John E., Cox, Nancy J., Dolan, M. Eileen

“…We report here the results of testing the pairwise association of 12,747 transcriptional gene-expression values with more than two million single-nucleotide…”
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Three-Dimensional Speckle Tracking Echocardiography for Assessment of Left Ventricular Function and Myocardial Mechanics after Pediatric Heart Transplantation by Lunze, F.I., Singh, T.P., Harrild, D., Gauvreau, K., Molloy, M.A., Narciso, R., Goncalves, A., Berger, F., Blume, E.D., Colan, S.D.

“…Three-dimensional (3D) echocardiography for the assessment of LV size, function and myocardial mechanics has been commonly used after heart transplantation…”
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“How are You Doing?”: Patient and Family Support Resources for Children on Ventricular Assist Device by Machado, D., Blume, E., Cousino, M., Sprague, C., Smyth, L., Rosenthal, D.N., Bleiweis, M.S., Lorts, A., May, L.J.

“…While psychiatric morbidity is associated with poor outcomes in adults on ventricular assist device (VAD), psychiatric concerns are often under recognized in…”
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Obesity Leads to Increased Mortality in Pediatric Heart Transplant Recipients - A Pediatric Heart Transplant Society Study by Bogle, C., Cantor, R., Koehl, D., Lochridge, J., Kirklin, J., Barnes, A., Wallis, G., Amdani, S., Ameduri, R., Pahl, E., Simpon, K., Blume, E.D.

“…The obesity epidemic has afflicted children of all ages with heart transplant (HT) recipients at significant risk compared to their pediatric counterpart. This…”
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Surface and subsurface microbial biomass, community structure and metabolic activity as a function of soil depth and season by Blume, E., Bischoff, M., Reichert, J.M., Moorman, T., Konopka, A., Turco, R.F.

“…Microbial biomass, size and community structure along with an estimate of microbial activity and soil chemical parameters were determined at three depths in…”
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Are graduate students rational? Evidence from the market for biomedical scientists by Blume-Kohout, Margaret E, Clack, John W

“…The U.S. National Institutes of Health (NIH) budget expansion from 1998 through 2003 increased demand for biomedical research, raising relative wages and total…”
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