Search Results - "Blumbach, Kai"
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Evaluation of Putative Biomarkers of Nephrotoxicity after Exposure to Ochratoxin A In Vivo and In Vitro
Published in Toxicological sciences (01-06-2008)“…The kidney is one of the main targets of xenobiotic-induced toxicity, but early detection of renal damage is difficult. Recently, several novel biomarkers of…”
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Journal Article -
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Ochratoxin A: 13-Week Oral Toxicity and Cell Proliferation in Male F344/N Rats
Published in Toxicological sciences (01-06-2007)“…Ochratoxin A (OTA) is nephrotoxic and a potent renal carcinogen. Male rats are most susceptible to OTA toxicity, and chronic administration of OTA (70 and 210…”
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Journal Article -
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Differences in Rat Models Used in Routine Toxicity Studies
Published in International Journal of Toxicology (01-03-2011)“…The discussion on whether the Sprague Dawley (SD), the Fischer F344, or the Hannover Wistar rat is the most appropriate model for toxicity studies in rodents…”
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Book Review Journal Article -
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Pathology in Continuous Infusion Studies in Rodents and Non-Rodents and ITO (Infusion Technology Organisation)-Recommended Protocol for Tissue Sampling and Terminology for Procedure-Related Lesions
Published in Journal of Toxicologic Pathology (01-06-2011)“…[Abstract]: Many variables may affect the outcome of continuous infusion studies. The results largely depend on the experience of the laboratory performing…”
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Journal Article -
5
Pathology in Continuous Infusion Studies in Rodents andNon-Rodents and ITO (Infusion Technology Organisation)-Recommended Protocol for Tissue Sampling and Terminology for Procedure-Related Lesions
Published in Journal of Toxicologic Pathology (01-01-2011)“…Many variables may affect the outcome of continuous infusion studies. The results largely depend on the experience of the laboratory performing these studies,…”
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Journal Article -
6
Quantitation of α2u-Globulin in Rat Kidney Cytosol by Capillary Electrophoresis
Published in Analytical biochemistry (01-02-1999)“…The renal accumulation of α2u-globulin has been implicated in the tumorigenicity of many nongenotoxic chemicals to the kidney of the male rat. Several…”
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Biotransformation and Male Rat-Specific Renal Toxicity of Diethyl Ethyl- and Dimethyl Methylphosphonate
Published in Toxicological sciences (01-01-2000)“…Dimethyl methylphosphonate (DMMP) is a widely used chemical. Diethyl ethylphosphonate (DEEP) has been proposed as a replacement for DMMP in several…”
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Journal Article