Search Results - "Blum, Thorsten B"

Seeded Heteroepitaxial Growth of Crystallizable Collagen Triple Helices: Engineering Multifunctional Two-Dimensional Core–Shell Nanostructures by Merg, Andrea D, van Genderen, Eric, Bazrafshan, Alisina, Su, Hanquan, Zuo, Xiaobing, Touponse, Gavin, Blum, Thorsten B, Salaita, Khalid, Abrahams, Jan Pieter, Conticello, Vincent P

“…Engineering free-standing 2D nanomaterials with compositional, spatial, and functional control across size regimes from the nano- to mesoscale represents a…”
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VASH1-SVBP and VASH2-SVBP generate different detyrosination profiles on microtubules by Ramirez-Rios, Sacnicte, Choi, Sung Ryul, Sanyal, Chadni, Blum, Thorsten B, Bosc, Christophe, Krichen, Fatma, Denarier, Eric, Soleilhac, Jean-Marc, Blot, Béatrice, Janke, Carsten, Stoppin-Mellet, Virginie, Magiera, Maria M, Arnal, Isabelle, Steinmetz, Michel O, Moutin, Marie-Jo

“…The detyrosination/tyrosination cycle of α-tubulin is critical for proper cell functioning. VASH1-SVBP and VASH2-SVBP are ubiquitous enzymes involved in…”
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Structural basis of connexin-36 gap junction channel inhibition by Ding, Xinyue, Aureli, Simone, Vaithia, Anand, Lavriha, Pia, Schuster, Dina, Khanppnavar, Basavraj, Li, Xiaodan, Blum, Thorsten B., Picotti, Paola, Gervasio, Francesco L., Korkhov, Volodymyr M.

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Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows by Blum, Thorsten B., Hahn, Alexander, Meier, Thomas, Davies, Karen M., Kühlbrandt, Werner

“…Mitochondrial ATP synthases form dimers, which assemble into long ribbons at the rims of the inner membrane cristae. We reconstituted detergent-purified…”
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Conserved in situ arrangement of complex I and III₂ in mitochondrial respiratory chain supercomplexes of mammals, yeast, and plants by Davies, Karen M., Blum, Thorsten B., Kühlbrandt, Werner

“…We used electron cryo-tomography and subtomogram averaging to investigate the structure of complex I and its supramolecular assemblies in the inner…”
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Visualization of ATP synthase dimers in mitochondria by electron cryo-tomography by Davies, Karen M, Daum, Bertram, Gold, Vicki A M, Mühleip, Alexander W, Brandt, Tobias, Blum, Thorsten B, Mills, Deryck J, Kühlbrandt, Werner

“…Electron cryo-tomography is a powerful tool in structural biology, capable of visualizing the three-dimensional structure of biological samples, such as cells,…”
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Cryo‐electron Microscopy Imaging of Alzheimer's Amyloid‐beta 42 Oligomer Displayed on a Functionally and Structurally Relevant Scaffold by Wu, Jinming, Blum, Thorsten B., Farrell, Daniel P, DiMaio, Frank, Abrahams, Jan Pieter, Luo, Jinghui

“…Amyloid‐β peptide (Aβ) oligomers are pathogenic species of amyloid aggregates in Alzheimer's disease. Like certain protein toxins, Aβ oligomers permeabilize…”
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The wild-type flagellar filament of the Firmicute Kurthia at 2.8 Å resolution in vivo by Blum, Thorsten B., Filippidou, Sevasti, Fatton, Mathilda, Junier, Pilar, Abrahams, Jan Pieter

“…Bacteria swim and swarm by rotating the micrometers long, helical filaments of their flagella. They change direction by reversing their flagellar rotation,…”
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Rational Design of a Novel Tubulin Inhibitor with a Unique Mechanism of Action by Mühlethaler, Tobias, Milanos, Lampros, Ortega, Jose Antonio, Blum, Thorsten B., Gioia, Dario, Roy, Bibhas, Prota, Andrea E., Cavalli, Andrea, Steinmetz, Michel O.

“…In this study, we capitalized on our previously performed crystallographic fragment screen and developed the antitubulin small molecule Todalam with only two…”
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Shape-Shifting Peptide Nanomaterials: Surface Asymmetry Enables pH-Dependent Formation and Interconversion of Collagen Tubes and Sheets by Merg, Andrea D, Touponse, Gavin, Genderen, Eric van, Blum, Thorsten B, Zuo, Xiaobing, Bazrafshan, Alisina, Siaw, Hew Ming Helen, McCanna, Arthur, Brian Dyer, R, Salaita, Khalid, Abrahams, Jan Pieter, Conticello, Vincent P

“…The fabrication of dynamic, transformable biomaterials that respond to environmental cues represents a significant step forward in the development of synthetic…”
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A lipocalin mediates unidirectional heme biomineralization in malaria parasites by Matz, Joachim M., Drepper, Benjamin, Blum, Thorsten B., van Genderen, Eric, Burrell, Alana, Martin, Peer, Stach, Thomas, Collinson, Lucy M., Abrahams, Jan Pieter, Matuschewski, Kai, Blackman, Michael J.

“…During blood-stage development, malaria parasites are challenged with the detoxification of enormous amounts of heme released during the proteolytic catabolism…”
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Conserved in situ arrangement of complex I and III 2 in mitochondrial respiratory chain supercomplexes of mammals, yeast, and plants by Davies, Karen M, Blum, Thorsten B, Kühlbrandt, Werner

“…We used electron cryo-tomography and subtomogram averaging to investigate the structure of complex I and its supramolecular assemblies in the inner…”
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Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals by Blum, Thorsten B., Housset, Dominique, Clabbers, Max T. B., van Genderen, Eric, Bacia-Verloop, Maria, Zander, Ulrich, McCarthy, Andrew A., Schoehn, Guy, Ling, Wai Li, Abrahams, Jan Pieter

“…Electron diffraction allows protein structure determination when only nanosized crystals are available. Nevertheless, multiple elastic (or dynamical)…”
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Cryptosporulation in Kurthia spp. forces a rethinking of asporogenesis in Firmicutes by Fatton, Mathilda, Filippidou, Sevasti, Junier, Thomas, Cailleau, Guillaume, Berge, Matthieu, Poppleton, Daniel, Blum, Thorsten B., Kaminek, Marek, Odriozola, Adolfo, Blom, Jochen, Johnson, Shannon L., Abrahams, Jan Pieter, Chain, Patrick S., Gribaldo, Simonetta, Tocheva, Elitza I., Zuber, Benoît, Viollier, Patrick H., Junier, Pilar

“…Endosporulation is a complex morphophysiological process resulting in a more resistant cellular structure that is produced within the mother cell and is called…”
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Cryo‐electron Microscopy Imaging of Alzheimer's Amyloid‐beta 42 Oligomer Displayed on a Functionally and Structurally Relevant Scaffold by Wu, Jinming, Blum, Thorsten B., Farrell, Daniel P, DiMaio, Frank, Abrahams, Jan Pieter, Luo, Jinghui

“…Amyloid‐β peptide (Aβ) oligomers are pathogenic species of amyloid aggregates in Alzheimer's disease. Like certain protein toxins, Aβ oligomers permeabilize…”
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Rational Design of a Novel Tubulin Inhibitor with a Unique Mechanism of Action by Mühlethaler, Tobias, Milanos, Lampros, Ortega, Jose Antonio, Blum, Thorsten B., Gioia, Dario, Roy, Bibhas, Prota, Andrea E., Cavalli, Andrea, Steinmetz, Michel O.

“…In this study, we capitalized on our previously performed crystallographic fragment screen and developed the antitubulin small molecule Todalam with only two…”
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Conserved in situ arrangement of complex I and III^sub 2^ in mitochondrial respiratory chain supercomplexes of mammals, yeast, and plants by Davies, Karen M, Blum, Thorsten B, Kühlbrandt, Werner

“…We used electron cryo-tomography and subtomogram averaging to investigate the structure of complex I and its supramolecular assemblies in the inner…”
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Abstract OR-8: High-Resolution Structures of Microtubule-Drug Complexes Revealed by Cryo-EM by Sejwal, Kushal, Blum, Thorsten, Atherton, Joseph, Sharma, Ashwani, Olieric, Natacha, Prota, Andrea, Moores, Carolyn, Steinmetz, Michel

“…Background: Microtubules are dynamic protein filaments that are crucial for cell division and constitute key elements of the cytoskeleton. They are assembled…”
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Visualization of ATP Synthase Dimers in Mitochondria by Electron Cryo-tomography by Davies, Karen M., Daum, Bertram, Gold, Vicki A. M., Mühleip, Alexander W., Brandt, Tobias, Blum, Thorsten B., Mills, Deryck J., Kühlbrandt, Werner

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