Search Results - "Blum, Suzanne A."

Opportunities and challenges in single-molecule and single-particle fluorescence microscopy for mechanistic studies of chemical reactions by Cordes, Thorben, Blum, Suzanne A.

“…Single-molecule and -particle fluorescence microscopy — traditionally applied to biophysical studies — has recently been used to gain insight into chemical…”
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Boron–Heteroatom Addition Reactions via Borylative Heterocyclization: Oxyboration, Aminoboration, and Thioboration by Issaian, Adena, Tu, Kim N, Blum, Suzanne A

“…Conspectus Organoboron compounds and heterocycles are powerful building blocks and precursors for organic synthesis, including for drug discovery and…”
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Catalyst-Free Synthesis of Borylated Lactones from Esters via Electrophilic Oxyboration by Faizi, Darius J, Issaian, Adena, Davis, Ashlee J, Blum, Suzanne A

“…A catalyst-free oxyboration reaction of alkynes is developed. The resulting borylated iso­coumarins and 2-pyrones are isolated as boronic acids,…”
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Role of LiCl in Generating Soluble Organozinc Reagents by Feng, Chao, Cunningham, Drew W, Easter, Quinn T, Blum, Suzanne A

“…The sensitivity provided by fluorescence microscopy enabled the observation of surface intermediates in the synthesis of soluble organozinc reagents by direct…”
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Catalyst-Free Formal Thioboration to Synthesize Borylated Benzothiophenes and Dihydrothiophenes by Faizi, Darius J., Davis, Ashlee J., Meany, Fiach B., Blum, Suzanne A.

“…The first ring‐forming thioboration reaction of C−C π bonds is reported. This catalyst‐free method proceeds in the presence of a commercially available…”
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Catalyzed Catalysis Using Carbophilic Lewis Acidic Gold and Lewis Basic Palladium: Synthesis of Substituted Butenolides and Isocoumarins by Shi, Yili, Roth, Katrina E, Ramgren, Stephen D, Blum, Suzanne A

“…A new strategy for gold and palladium dual-catalytic reactivity and turnover, called catalyzed catalysis, enhanced the synthetic usefulness of vinylgold…”
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Selectivity, Compatibility, Downstream Functionalization, and Silver Effect in the Gold and Palladium Dual-Catalytic Synthesis of Lactones by Al-Amin, Mohammad, Johnson, Joel S, Blum, Suzanne A

“…The chemo- and regioselectivity and functional group compatibility in gold and palladium cooperatively catalyzed cross-coupling reactions were determined in…”
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Structure–Reactivity Studies, Characterization, and Transformation of Intermediates by Lithium Chloride in the Direct Insertion of Alkyl and Aryl Iodides to Metallic Zinc Powder by Feng, Chao, Easter, Quinn T, Blum, Suzanne A

“…Employment of fluorophore-tagged alkyl and aryl iodides permitted detection of persistent surface intermediates during their direct insertion to commercially…”
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Relative Kinetic Basicities of Organogold Compounds by Roth, Katrina E, Blum, Suzanne A

“…The relative kinetic basicities of a series of differentially substituted and hybridized neutral organogold compounds were examined through competitive…”
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Palladium-Catalyzed Carboauration of Alkynes and Palladium/Gold Cross-Coupling by Shi, Yili, Ramgren, Stephen D, Blum, Suzanne A

“…A new palladium-catalyzed syn carboauration of alkynes proceeds in 2 h at ambient temperature with complete regioselectivity. The resulting α-ester vinyl−gold…”
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Phase Separation Polymerization of Dicyclopentadiene Characterized by In Operando Fluorescence Microscopy by Hensle, Eva M, Blum, Suzanne A

“…Phase separation polymerization of dicyclopentadiene has been characterized from initiation to bulk material formation for the first time via in operando…”
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Structure–Reactivity Studies of Intermediates for Mechanistic Information by Subensemble Fluorescence Microscopy by Kitagawa, Kazuhiro, Blum, Suzanne A

“…Not provided…”
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Gold and Rhodium Transmetalation: Mechanistic Insights and Dual-Metal Reactivity by Shi, Yili, Blum, Suzanne A

“…A transmetalation reaction between rhodium(III) and sp2- and sp3-hybridized organogold(I) compounds proceeds rapidly at ambient temperature (15 min to 6 h)…”
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Mechanistic Studies of Azaphilic versus Carbophilic Activation by Gold(I) in the Gold/Palladium Dual-Catalyzed Rearrangement of Alkenyl Vinyl Aziridines by Hirner, Joshua J, Roth, Katrina E, Shi, Yili, Blum, Suzanne A

“…A vinyl aziridine activation strategy cocatalyzed by palladium(0) and a gold(I) Lewis acid has been developed. This rearrangement installs a C–C and a C–N bond…”
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Mechanistic Studies of Formal Thioboration Reactions of Alkynes by Issaian, Adena, Faizi, Darius J, Bailey, Johnathan O, Mayer, Peter, Berionni, Guillaume, Singleton, Daniel A, Blum, Suzanne A

“…Several formal heteroborylative cyclization reactions have been recently reported, but little physical–organic and mechanistic data are known. We now…”
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Nickel-Catalyzed Cross-Coupling of Organogold Reagents by Hirner, Joshua J, Blum, Suzanne A

“…Organogold compounds undergo nickel-catalyzed cross-coupling reactions with aryl and vinyl bromides in high yield under mild conditions. The reaction tolerates…”
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Surfactant Micellar and Vesicle Microenvironments and Structures under Synthetic Organic Conditions by Peacock, Hannah, Blum, Suzanne A.

“…Fluorescence lifetime imaging microscopy (FLIM) reveals vesicle sizes, structures, microenvironments, reagent partitioning, and system evolution with two…”
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Real-Time Polymer Viscosity–Catalytic Activity Relationships on the Microscale by Eivgi, Or, Blum, Suzanne A.

“…Polymer growth induces physical changes to catalyst microenvironments. Here, these physical changes are quantified in real time and are found to influence…”
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Aminoboration: Addition of B–N σ Bonds across C–C π Bonds by Chong, Eugene, Blum, Suzanne A

“…This communication demonstrates the first catalytic aminoboration of C–C π bonds by B–N σ bonds and its application to the synthesis of 3-borylated indoles…”
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Single-Micelle and Single-Zinc-Particle Imaging Provides Insights into the Physical Processes Underpinning Organozinc Reactions in Water by Peacock, Hannah, Blum, Suzanne A

“…Micelles on the surfaces of individual metallic zinc particles are imaged by fluorescence microscopy with sensitivity up to single micelles. These micelles are…”
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