Search Results - "Blum, Manuel R"

Atherosclerotic Cardiovascular Disease Risk Prediction in Disaggregated Asian and Hispanic Subgroups Using Electronic Health Records by Rodriguez, Fatima, Chung, Sukyung, Blum, Manuel R, Coulet, Adrien, Basu, Sanjay, Palaniappan, Latha P

“…Background Risk assessment is the cornerstone for atherosclerotic cardiovascular disease ( ASCVD ) treatment decisions. The Pooled Cohort Equations ( PCE )…”
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Is there a shift from cardiovascular to cancer death in lipid-lowering trials? A systematic review and meta-analysis by Bolt, Lucy, Speierer, Alexandre, Bétrisey, Sylvain, Aeschbacher-Germann, Martina, Blum, Manuel R, Gencer, Baris, Del Giovane, Cinzia, Aujseky, Drahomir, Moutzouri, Elisavet, Rodondi, Nicolas

“…Lipid-lowering therapy (LLT) reduces cardiovascular (CV) events, but data are conflicting on all-cause mortality, especially among older adults. Though LLT…”
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Trueperella pyogenes endocarditis in a Swiss farmer: a case report and review of the literature by Stuby, Johann, Lardelli, Patrizia, Thurnheer, Christine M, Blum, Manuel R, Frei, Andrea N

“…Abstract Background Trueperella pyogenes ( T. pyogenes ) is a bacterium that colonizes the skin and mucosal surfaces of various domestic and wild animals. It…”
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Lipid-Lowering Trials Are Not Representative of Patients Managed in Clinical Practice: A Systematic Review and Meta-Analysis of Exclusion Criteria by Aeschbacher-Germann, Martina, Kaiser, Nathalie, Speierer, Alexandre, Blum, Manuel R, Bauer, Douglas C, Del Giovane, Cinzia, Aujesky, Drahomir, Gencer, Baris, Rodondi, Nicolas, Moutzouri, Elisavet

“…Background Randomized clinical trials (RCTs) might not be representative of the real-world population because of unreasonable exclusion criteria. We sought to…”
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Achilles tendon ultrasonography in the clinical screening of familial hypercholesterolaemia – a cross-sectional analysis by De Montmollin, Maria, Bétrisey, Sylvain, Feller, Martin, Moutzouri, Elisavet, Blum, Manuel R., Amsler, Jennifer, Papazoglou, Dimitrios D., Möller, Burkhard, Rodondi, Nicolas

“…BACKGROUND AND AIMS: People with familial hypercholesterolaemia are 13 times more likely to develop cardiovascular disease than the general population…”
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Lipid-Lowering Therapy and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Bétrisey, Sylvain, Haller, Moa Lina, Efthimiou, Orestis, Speierer, Alexandre, Del Giovane, Cinzia, Moutzouri, Elisavet, Blum, Manuel R, Aujesky, Drahomir, Rodondi, Nicolas, Gencer, Baris

“…There is debate over whether statins increase risk of hemorrhagic stroke, so we assessed current evidence, including data from new statin trials and trials of…”
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Tolerability of statin-based management of patients with a history of statin-associated muscle symptoms: protocol for a systematic review by Villoz, Fanny, Lyko, Christina, Del Giovane, Cinzia, Rodondi, Nicolas, Blum, Manuel R

“…IntroductionStatin-associated muscle symptoms (SAMSs) are a major clinical issue in the primary and secondary prevention of cardiovascular events. Current…”
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Adjunct prednisone in community-acquired pneumonia: 180-day outcome of a multicentre, double-blind, randomized, placebo-controlled trial by Blum, Claudine A, Roethlisberger, Eva A, Cesana-Nigro, Nicole, Winzeler, Bettina, Rodondi, Nicolas, Blum, Manuel R, Briel, Matthias, Mueller, Beat, Christ-Crain, Mirjam, Schuetz, Philipp

“…Several trials and meta-analyses found a benefit of adjunct corticosteroids for community-acquired pneumonia with respect to short-term outcome, but there is…”
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Renal Function and Body Mass Index Contribute to Serum Neurofilament Light Chain Levels in Elderly Patients With Atrial Fibrillation by Polymeris, Alexandros A, Helfenstein, Fabrice, Benkert, Pascal, Aeschbacher, Stefanie, Leppert, David, Coslovsky, Michael, Willemse, Eline, Schaedelin, Sabine, Blum, Manuel R, Rodondi, Nicolas, Reichlin, Tobias, Moschovitis, Giorgio, Wuerfel, Jens, De Marchis, Gian Marco, Engelter, Stefan T, Lyrer, Philippe A, Conen, David, Kühne, Michael, Osswald, Stefan, Bonati, Leo H, Kuhle, Jens

“…Serum neurofilament light chain (sNfL) is increasingly used as a neuroaxonal injury biomarker in the elderly. Besides age, little is known about how other…”
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The importance of intravenous immunoglobulin treatment in critically ill patients with necrotizing soft tissue infection: a retrospective cohort study by Hofmaenner, Daniel A, Wendel Garcia, Pedro David, Blum, Manuel R, David, Sascha, Schuepbach, Reto A, Buehler, Philipp K, Frey, Pascal M, Zinkernagel, Annelies S, Brugger, Silvio D

“…Necrotizing soft-tissue infections are infections with high mortality. The use of immunoglobulins within a combination therapy including broad-spectrum…”
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Bone Morphogenetic Protein 10-A Novel Biomarker to Predict Adverse Outcomes in Patients With Atrial Fibrillation by Hennings, Elisa, Blum, Steffen, Aeschbacher, Stefanie, Coslovsky, Michael, Knecht, Sven, Eken, Ceylan, Lischer, Mirko, Paladini, Rebecca E, Krisai, Philipp, Reichlin, Tobias, Rodondi, Nicolas, Beer, Jürg H, Ammann, Peter, Conte, Giulio, De Perna, Maria Luisa, Kobza, Richard, Blum, Manuel R, Bossard, Matthias, Kastner, Peter, Ziegler, André, Müller, Christian, Bonati, Leo H, Pfister, Otmar, Zuern, Christine S, Conen, David, Kühne, Michael, Osswald, Stefan

“…Background Patients with atrial fibrillation (AF) face an increased risk of death and major adverse cardiovascular events (MACE). We aimed to assess the…”
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Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials by Zijlstra, Laurien E, Jukema, J Wouter, Westendorp, Rudi G J, Du Puy, Robert S, Poortvliet, Rosalinde K E, Kearney, Patricia M, O'Keeffe, Linda, Dekkers, Olaf M, Blum, Manuel R, Rodondi, Nicolas, Collet, Tinh-Hai, Quinn, Terence J, Sattar, Naveed, Stott, David J, Trompet, Stella, den Elzen, Wendy P J, Gussekloo, Jacobijn, Mooijaart, Simon P

“…The cardiovascular effects of treating older adults with subclinical hypothyroidism (SCH) are uncertain. Although concerns have been raised regarding a…”
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County-Level Factors Associated With Cardiovascular Mortality by Race/Ethnicity by Zuma, Bongeka Z, Parizo, Justin T, Valencia, Areli, Spencer-Bonilla, Gabriela, Blum, Manuel R, Scheinker, David, Rodriguez, Fatima

“…Background Persistent racial/ethnic disparities in cardiovascular disease (CVD) mortality are partially explained by healthcare access and socioeconomic,…”
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Biomarkers of Inflammation and Risk of Hospitalization for Heart Failure in Patients With Atrial Fibrillation by Benz, Alexander P, Aeschbacher, Stefanie, Krisai, Philipp, Moschovitis, Giorgio, Blum, Steffen, Meyre, Pascal, Blum, Manuel R, Rodondi, Nicolas, Di Valentino, Marcello, Kobza, Richard, De Perna, Maria Luisa, Bonati, Leo H, Beer, Jürg H, Kühne, Michael, Osswald, Stefan, Conen, David

“…Background Hospitalization for heart failure (HF) is very common in patients with atrial fibrillation (AF). We hypothesized that biomarkers of inflammation can…”
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Patient and physician gender concordance in preventive care in university primary care settings by Krähenmann-Müller, Simone, Virgini, Vanessa S, Blum, Manuel R, da Costa, Bruno R, Collet, Tinh-Hai, Martin, Yonas, Cornuz, Jacques, Zimmerli, Lukas, Gaspoz, Jean-Michel, Bauer, Douglas C, Kerr, Eve A, Aujesky, Drahomir, Rodondi, Nicolas

“…Abstract Objective To assess the quality of preventive care according to physician and patient gender in a country with universal health care coverage. Methods…”
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Use of E-values for addressing confounding in observational studies-an empirical assessment of the literature by Blum, Manuel R, Tan, Yuan Jin, Ioannidis, John P A

“…E-values are a recently introduced approach to evaluate confounding in observational studies. We aimed to empirically assess the current use of E-values in…”
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How does exercise treatment compare with antihypertensive medications? A network meta-analysis of 391 randomised controlled trials assessing exercise and medication effects on systolic blood pressure by Naci, Huseyin, Salcher-Konrad, Maximilian, Dias, Sofia, Blum, Manuel R, Sahoo, Samali Anova, Nunan, David, Ioannidis, John P A

“…To compare the effect of exercise regimens and medications on systolic blood pressure (SBP). Medline (via PubMed) and the Cochrane Library. Randomised…”
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Heart rate and adverse outcomes in patients with prevalent atrial fibrillation by Moschovitis, Giorgio, Johnson, Linda S B, Blum, Steffen, Aeschbacher, Stefanie, De Perna, Maria Luisa, Pagnamenta, Alberto, Mayer Melchiorre, Patrizia Assunta, Benz, Alexander P, Kobza, Richard, Di Valentino, Marcello, Zuern, Christine S, Auricchio, Angelo, Conte, Giulio, Rodondi, Nicolas, Blum, Manuel R, Beer, Juerg H, Kühne, Michael, Osswald, Stefan, Conen, David

“…ObjectiveThe optimal target heart rate in patients with prevalent atrial fibrillation (AF) is not well defined. The aim of this study was to analyse the…”
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Multimethod, multidataset analysis reveals paradoxical relationships between sociodemographic factors, Hispanic ethnicity and diabetes by Knight, Gabriel M, Spencer-Bonilla, Gabriela, Maahs, David M, Blum, Manuel R, Valencia, Areli, Zuma, Bongeka Z, Prahalad, Priya, Sarraju, Ashish, Rodriguez, Fatima, Scheinker, David

“…IntroductionPopulation-level and individual-level analyses have strengths and limitations as do ‘blackbox’ machine learning (ML) and traditional, interpretable…”
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Limitations and Misinterpretations of E-Values for Sensitivity Analyses of Observational Studies by Ioannidis, John P A, Tan, Yuan Jin, Blum, Manuel R

“…The E-value was recently introduced on the basis of earlier work as "the minimum strength of association…that an unmeasured confounder would need to have with…”
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