Search Results - "Blum, Ailisa"
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Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-2020)“…None of the current superresolution microscopy techniques can reliably image the changes in endogenous protein nanoclustering dynamics associated with specific…”
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Nucleotide-dependent farnesyl switch orchestrates polymerization and membrane binding of human guanylate-binding protein 1
Published in Proceedings of the National Academy of Sciences - PNAS (11-07-2017)“…Dynamin-like proteins (DLPs) mediate various membrane fusion and fission processes within the cell, which often require the polymerization of DLPs. An…”
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SORTING NEXIN1 Is Required for Modulating the Trafficking and Stability of the Arabidopsis IRON-REGULATED TRANSPORTER1
Published in The Plant cell (01-03-2014)“…Dicotyledonous plants growing under limited iron availability initiate a response resulting in the solubilization, reduction, and uptake of soil iron. The…”
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Hormone influence on the spatial regulation of IRT1 expression in iron-deficient Arabidopsis thaliana roots
Published in Plant signaling & behavior (10-04-2014)“…The IRON-REGULATED TRANSPORTER1 (IRT1) is the principal importer of soil iron in Arabidopsis thaliana. It has a complex intracellular trafficking behavior,…”
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Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG‐Syt1‐SV2 plasma membrane nanocluster for synaptic vesicle entry
Published in The EMBO journal (03-07-2023)“…The unique nerve terminal targeting of botulinum neurotoxin type A (BoNT/A) is due to its capacity to bind two receptors on the neuronal plasma membrane:…”
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A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity
Published in Nucleic acids research (08-11-2021)“…Abstract Few genetically dominant mutations involved in human disease have been fully explained at the molecular level. In cases where the mutant gene encodes…”
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Nanoscale enrichment of the cytosolic enzyme trichodiene synthase near reorganized endoplasmic reticulum in Fusarium graminearum
Published in Fungal genetics and biology (01-03-2019)“…[Display omitted] •3D SIM revealed differences in localization patterns of fungal cytosolic enzymes.•The cytosolic trichodiene synthase Tri5 was enriched at…”
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High-throughput FACS-based mutant screen identifies a gain-of-function allele of the Fusarium graminearum adenylyl cyclase causing deoxynivalenol over-production
Published in Fungal genetics and biology (01-05-2016)“…•Novel high-throughput mutant screen for Fusarium spores was established using FACS.•Confirmation through the identification and characterisation of the g8…”
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Regulation of a novel Fusarium cytokinin in Fusarium pseudograminearum
Published in Fungal biology (01-03-2019)“…Fusarium pseudograminearum is an agronomically important fungus, which infects many crop plants, including wheat, where it causes Fusarium crown rot. Like many…”
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Super-resolving botulinum neurotoxin type A molecules: from surface landing to internalization in synaptic vesicles
Published in Toxicon (Oxford) (01-12-2018)Get full text
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Hormone influence on the spatial regulation of IRT1 expression in iron-deficient Arabidopsis thaliana roots
Published in Plant Signaling & Behavior (01-06-2014)“…The IRON-REGULATED TRANSPORTER1 (IRT1) is the principal importer of soil iron in Arabidopsis thaliana. It has a complex intracellular trafficking behavior,…”
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