Search Results - "Bluhterova, N. V."
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Polyacrylates of Metals Are a New Class of the Potential Antitumor Drugs
Published in Russian journal of physical chemistry. B (01-11-2019)“…— The results of preclinical study of the original antitumor drug aurumacryl (gold polyacrylate), which belongs to polyacrylates of metals (PAMs), a new class…”
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2
Experimental study of the antitumor effect of aurumacryl
Published in Russian chemical bulletin (01-12-2017)“…Gold polyacrylate (aurumacryl) belonging to a new class of compounds for oncology — metal polyacrylates — was shown to exhibit strong antitumor activity…”
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3
The Mechanism of the Cytotoxic Effect of Noble Metal Polyacrylates on Tumor Cells
Published in Biophysics (Oxford) (01-12-2023)“…A comparative study of the cytotoxic activity and mechanism of action of polyacrylates containing gold (aurumacryl) and silver (argacryl) against human tumor…”
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4
Nanotechnologies for Drug Therapy of Malignant Tumors
Published in Biophysics (Oxford) (01-06-2023)“…This review summarizes experimental data related to the study of the possibilities of using nanotechnology for the drug therapy of malignant tumors…”
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5
Noble Metal Polyacrylates: Cytotoxicity against Cisplatin- and Doxorubicin-Resistant Tumor Cells
Published in Biophysics (Oxford) (01-10-2022)“…The cytotoxic activity of metal polyacrylates containing gold (aurumacryl) or silver (argacryl) has been studied in human breast cancer cell cultures sensitive…”
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6
Antitumor and Cytotoxic Effect of Silver Polyacrylate
Published in Biophysics (Oxford) (2024)“…Silver polyacrylate (argacryl) is shown to have antitumor activity in models of solid mouse tumors in vivo and a cytotoxic effect on human tumor cells in…”
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7
Gold and Silver Compounds as Potential Antitumor Drugs
Published in Biophysics (Oxford) (2024)“…The generalized results of the study of antitumor activity, cytotoxic effect, and mechanism of action of gold (aurumacryl) and silver (argacryl) polyacrylates…”
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The Sensitivity of Malignant and Healthy Human Cells to Polyacrylates of Noble Metals
Published in Biophysics (Oxford) (01-02-2022)“…—The cytotoxic activities of two polyacrylate-based polymer compounds containing gold (aurumacryl) and silver (argacryl) against malignant (MCF-7 breast…”
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9
Gold Nanoparticles as Potential Radiosensitizing and Cytotoxic Agents
Published in Biophysics (Oxford) (01-11-2021)“…—This review summarizes the data on the radiosensitizing properties and cytotoxic activity of gold nanoparticles obtained in studies of experimental tumor…”
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10
Role of the Nitrosonium Cation in the Mechanism Underlying the Antitumor Effects of Drugs in Combination with Dinitrosyl Iron Complexes
Published in Biophysics (Oxford) (2022)“…This work is dedicated to the mechanism of the antitumor action of dinitrosyl iron complexes, which generate nitric oxide NO and nitrosonium cations, NO + …”
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Cytotoxicity of Silver Compounds
Published in Biophysics (Oxford) (2022)“…This review summarizes experimental data obtained in studies of the cytotoxic activity of silver-containing compounds against human tumor cell lines. Putative…”
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12
Silver Nanoparticles: Cytotoxic Activity and Mechanisms of Action
Published in Biophysics (Oxford) (2022)“…— Experimental data obtained in studies of the cytotoxic and antitumor activity of silver nanoparticles and the underlying mechanisms are reviewed…”
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13
The Nitrosonium Cation as a Component of Dinitrosyl Iron Complexes Mediates their Antitumor Effect
Published in Biophysics (Oxford) (01-11-2021)“…—The antitumor efficacy of the combined use of the binuclear dinitrosyl iron complex with glutathione as an exogenous donor of cytotoxic nitrosonium cations…”
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14
The Antitumor and Cytotoxic Effects of Polyacrylates of Noble Metals
Published in Biophysics (Oxford) (01-09-2021)“…We compared the antitumor and cytotoxic activities of two polyacrylic acid-based compounds containing gold (aurumacryl) and silver (argacryl). The tested…”
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15
Antitumor Efficacy of the Combined Use of Gold Polyacrylate (Aurumacryl) and Radiation Therapy in an Experiment
Published in Biophysics (Oxford) (01-08-2022)“…The ability of gold polyacrylate (aurumacryl) to increase the sensitivity of murine tumor (В-16/F10 melanoma) to radiation treatment has been explored…”
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16
Nitric Oxide Donors: The Antitumor and Cytotoxic Effects of the Binuclear Dinitrosyl Iron Complex with N-Acetylcysteine
Published in Biophysics (Oxford) (01-11-2021)“…—The antitumor and cytotoxic actions of the binuclear dinitrosyl iron complex with N -acetylcysteine have been investigated by using a mouse solid tumor…”
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17
The Cytotoxic Effect of Gold Polyacrylate (Aurumacryl) on Human Skin Fibroblasts
Published in Biophysics (Oxford) (01-11-2020)“…The cytotoxic effect of the potential antitumor drug aurumacryl (gold polyacrylate) on human skin fibroblast cell line hFB-hTERT6 has been studied in vitro. It…”
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The Sensitivity of Human Tumor Cells to the Cytotoxicity of Gold Polyacrylate (Aurumacryl)
Published in Biophysics (Oxford) (01-11-2019)“…The cytotoxic effect of the antitumor drug aurumacryl (gold polyacrylate) against human tumor cells of various origins has been studied. It has been shown that…”
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19
Experimental Comparison of the Antitumor Activities of Aurumacryl and Cytostatics with Different Mechanisms of Action
Published in Biophysics (Oxford) (01-03-2020)“…—We have compared the antitumor activity of aurumacryl, a new cancer drug, and several well-known cytostatics with different mechanisms of action, that is,…”
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20
An Experimental Study of the Pharmacokinetics of the Antitumor Drug Aurumacryl
Published in Biophysics (Oxford) (01-05-2018)“…The distribution of the antitumor drug aurumacryl (intraperitoneally injected at a dose of 100 mg/kg) in the bodies of animals with Lewis lung carcinoma was…”
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