Search Results - "Blottiere, Herve M"

TLR ligands and butyrate increase Pyy expression through two distinct but inter‐regulated pathways by Larraufie, Pierre, Doré, Joël, Lapaque, Nicolas, Blottière, Hervé M.

“…Summary The intestinal epithelium is an active barrier separating the host from its microbiota. It senses microbial compounds through expression of a wide…”
Get full text

Identification of the novel role of butyrate as AhR ligand in human intestinal epithelial cells by Marinelli, Ludovica, Martin-Gallausiaux, Camille, Bourhis, Jean-Marie, Béguet-Crespel, Fabienne, Blottière, Hervé M., Lapaque, Nicolas

“…The ligand activated transcription factor, aryl hydrocarbon receptor (AhR) emerged as a critical regulator of immune and metabolic processes in the…”
Get full text

Neonatal Programming of Microbiota Composition: A Plausible Idea That Is Not Supported by the Evidence by Michel, Catherine, Blottière, Hervé M

“…Underpinning the theory "developmental origins of health and disease" (DOHaD), evidence is accumulating to suggest that the risks of adult disease are in part…”
Get full text

Roseburia, a decreased bacterial taxon in the gut microbiota of patients suffering from anorexia nervosa by Mondot, Stanislas, Lachkar, Laurine, Doré, Joël, Blottière, Hervé M., Hanachi, Mouna

“…Anorexia nervosa (AN) is a severe eating disorder which can lead to malnutrition and life threatening complications with high mortality rates. We designed our…”
Get full text

The gut bacterium and pathobiont Bacteroides vulgatus activates NF-κB in a human gut epithelial cell line in a strain and growth phase dependent manner by Ó Cuív, Páraic, de Wouters, Tomas, Giri, Rabina, Mondot, Stanislas, Smith, Wendy J., Blottière, Hervé M., Begun, Jakob, Morrison, Mark

“…The gut microbiota is increasingly implicated in the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC) although the identity of the bacteria…”
Get full text

Commensal gut bacteria modulate phosphorylation-dependent PPARγ transcriptional activity in human intestinal epithelial cells by Nepelska, Malgorzata, de Wouters, Tomas, Jacouton, Elsa, Béguet-Crespel, Fabienne, Lapaque, Nicolas, Doré, Joël, Arulampalam, Velmurugesan, Blottière, Hervé M.

“…In healthy subjects, the intestinal microbiota interacts with the host’s epithelium, regulating gene expression to the benefit of both, host and microbiota…”
Get full text

Inhibition of the NF-κB Pathway in Human Intestinal Epithelial Cells by Commensal Streptococcus salivarius by KACI, Ghalia, LAKHDARI, Omar, DORE, Joël, DUSKO EHRLICH, S, RENAULT, Pierre, BLOTTIERE, Herve M, DELORME, Christine

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Glutamate from the microbiome controls host metabolism by Le Dréan, Gwenola, Blottière, Hervé M.

“…In an attempt to investigate the role of enteroendocrine cells in the colon using elegant, targeted depletion tools, the authors of a study published in this…”
Get full text

Impact of pemetrexed chemotherapy on the gut microbiota and intestinal inflammation of patient-lung-derived tumor xenograft (PDX) mouse models by Pensec, Cindy, Gillaizeau, Florence, Guenot, Dominique, Bessard, Anne, Carton, Thomas, Leuillet, Sébastien, Campone, Mario, Neunlist, Michel, Blottière, Hervé M., Le Vacon, Françoise

“…Chemotherapy remains the gold standard for advanced cancer. Pemetrexed, a chemotherapeutic agent used in non-small cell lung cancer, can induce significant…”
Get full text

A fibrolytic potential in the human ileum mucosal microbiota revealed by functional metagenomic by Patrascu, Orlane, Béguet-Crespel, Fabienne, Marinelli, Ludovica, Le Chatelier, Emmanuelle, Abraham, Anne-Laure, Leclerc, Marion, Klopp, Christophe, Terrapon, Nicolas, Henrissat, Bernard, Blottière, Hervé M., Doré, Joël, Béra-Maillet, Christel

“…The digestion of dietary fibers is a major function of the human intestinal microbiota. So far this function has been attributed to the microorganisms…”
Get full text

Functional metagenomics to decipher food–microbe–host crosstalk by Larraufie, Pierre, de Wouters, Tomas, Potocki-Veronese, Gabrielle, Blottière, Hervé M., Doré, Joël

“…The recent developments of metagenomics permit an extremely high-resolution molecular scan of the intestinal microbiota giving new insights and opening…”
Get full text

Anti‐inflammatory properties of dairy lactobacilli by Santos Rocha, Clarissa, Lakhdari, Omar, Blottière, Hervé M., Blugeon, Sébastien, Sokol, Harry, Bermúdez‐Humarán, Luis G., Azevedo, Vasco, Miyoshi, Anderson, Doré, Joël, Langella, Philippe, Maguin, Emmanuelle, van de Guchte, Maarten

“…Background: The intestinal microbiota plays an important role in human health through the modulation of innate immune responses. While selected commensal…”
Get full text

The NF‐κB binding site located in the proximal region of the TSLP promoter is critical for TSLP modulation in human intestinal epithelial cells by Cultrone, Antonietta, de Wouters, Tomas, Lakhdari, Omar, Kelly, Denise, Mulder, Imke, Logan, Elizabeth, Lapaque, Nicolas, Doré, Joel, Blottière, Hervé M.

“…Thymic stromal lymphopoietin (TSLP) is constitutively secreted by intestinal epithelial cells. It regulates gut DCs, therefore, contributing to the maintenance…”
Get full text

Molecular analysis of the effect of short-chain fatty acids on intestinal cell proliferation by Blottiere, Herve M., Buecher, Bruno, Galmiche, Jean-Paul, Cherbut, Christine

“…Short-chain fatty acids (SCFA), particularly butyrate, were shown to regulate cell proliferation in vitro and in vivo. Indeed, butyrate is the major fuel for…”
Get full text

Degraded Carrageenan Causing Colitis in Rats Induces TNF Secretion and ICAM-1 Upregulation in Monocytes through NF-κB Activation by Benard, Claudine, Cultrone, Antonietta, Michel, Catherine, Rosales, Carlos, Segain, Jean-Pierre, Lahaye, Marc, Galmiche, Jean-Paul, Cherbut, Christine, Blottière, Hervé M.

“…Carrageenan (CGN) is a high molecular weight sulphated polysaccharide derived from red seaweeds. In rodents, its degraded forms (dCGN) can induce intestinal…”
Get full text

Milk fermented with a 15-lipoxygenase-1-producing Lactococcus lactis alleviates symptoms of colitis in a murine model by Saraiva, Tessalia D L, Morais, Katia, Pereira, Vanessa B, de Azevedo, Marcela, Rocha, Clarissa S, Prosperi, Camila C, Gomes-Santos, Ana C, Bermudez-Humaran, Luis, Faria, Ana M C, Blottiere, Herve M, Langella, Philippe, Miyoshi, Anderson, de LeBlanc, Alejandra de Moreno, LeBlanc, Jean G, Azevedo, Vasco

“…Inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, is characterized by extensive inflammation due to dysregulation of the…”
Get more information

Genome Sequence of "Candidatus Arthromitus" sp. Strain SFB-Mouse-NL, a Commensal Bacterium with a Key Role in Postnatal Maturation of Gut Immune Functions by Bolotin, Alexander, de Wouters, Tomas, Schnupf, Pamela, Bouchier, Christiane, Loux, Valentin, Rhimi, Moez, Jamet, Alexandre, Dervyn, Rozenn, Boudebbouze, Samira, Blottière, Hervé M, Sorokin, Alexei, Snel, Johannes, Cerf-Bensussan, Nadine, Gaboriau-Routhiau, Valérie, van de Guchte, Maarten, Maguin, Emmanuelle

“…"Candidatus Arthromitus" sp. strain SFB-mouse-NL (SFB, segmented filamentous bacteria) is a commensal bacterium necessary for inducing the postnatal maturation…”
Get full text

Impact of newly developed metagenomic tools on our knowledge of the gut microbiota and its role in human health: diagnostic and therapeutic issues by Blottière, Hervé M, Doré, Joël

“…Over the last years, our vision of the intestinal microbiota and its contribution to human physiology has been fully revisited, thanks to metagenomics. Next…”
Get more information

SCFA: mechanisms and functional importance in the gut by Martin-Gallausiaux, Camille, Marinelli, Ludovica, Blottière, Hervé M., Larraufie, Pierre, Lapaque, Nicolas

“…In recent years, the importance of the gut microbiota in human health has been revealed and many publications have highlighted its role as a key component of…”
Get full text

Energy balance and obesity: what are the main drivers? by Romieu, Isabelle, Dossus, Laure, Barquera, Simón, Blottière, Hervé M., Franks, Paul W., Gunter, Marc, Hwalla, Nahla, Hursting, Stephen D., Leitzmann, Michael, Margetts, Barrie, Nishida, Chizuru, Potischman, Nancy, Seidell, Jacob, Stepien, Magdalena, Wang, Youfa, Westerterp, Klaas, Winichagoon, Pattanee, Wiseman, Martin, Willett, Walter C.

“…Purpose The aim of this paper is to review the evidence of the association between energy balance and obesity. Methods In December 2015, the International…”
Get full text