Search Results - "Bloomstein, Joshua"

Merkel cell carcinoma treatment with Mohs micrographic surgery versus wide local excision: A retrospective cohort survival analysis by Bloomstein, Joshua D., Eisen, Daniel B.

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Impact of Gut Bacterial Metabolites on Psoriasis and Psoriatic Arthritis: Current Status and Future Perspectives by Lai, Yuhsien, Wu, Xuesong, Chao, Ellen, Bloomstein, Joshua D., Wei, Grace, Hwang, Sam T., Shi, Zhenrui

“…There is growing evidence that supports a role of gut dysbiosis in the pathogenesis of psoriasis (Pso). Thus, probiotic supplementation and fecal microbiota…”
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Complications of Deep Brain Stimulation for Parkinson Disease and Relationship between Micro-electrode tracks and hemorrhage: Systematic Review and Meta-Analysis by Rasiah, Neilen P., Maheshwary, Romir, Kwon, Churl-Su, Bloomstein, Joshua D., Girgis, Fady

“…Deep brain stimulation is a common treatment for Parkinson's disease (PD). Despite strong efficacy in well-selected patients, complications can occur…”
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Searching for biomarkers to help distinguish Merkel cell carcinoma from cutaneous small cell lung cancer with gene expression analysis by Bloomstein, Joshua D., Doost, Mohammad S., Meyer, Summer N., Kiuru, Maija, Eisen, Daniel B.

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Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination-deficient cancer models by Mehibel, Manal, Xu, Yu, Li, Caiyun G, Moon, Eui Jung, Thakkar, Kaushik N, Diep, Anh N, Kim, Ryan K, Bloomstein, Joshua D, Xiao, Yiren, Bacal, Julien, Saldivar, Joshua C, Le, Quynh-Thu, Cimprich, Karlene A, Rankin, Erinn B, Giaccia, Amato J

“…Hypoxia, a hallmark feature of the tumor microenvironment, causes resistance to conventional chemotherapy, but was recently reported to synergize with…”
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Gain-of-function of TRPM4 predisposes mice to psoriasiform dermatitis by Yamada, Daisuke, Vu, Simon, Wu, Xuesong, Shi, Zhenrui, Morris, Desiree, Bloomstein, Joshua D, Huynh, Mindy, Zheng, Jie, Hwang, Samuel T

“…Transient receptor potential melastatin 4 (TRPM4) is a Ca -activated, monovalent cation channel that is expressed in a wide range of cells. We previously…”
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Dose-Area Product–to–Effective Dose Conversion Coefficients for Pelvic Radiography Using a Monte Carlo Program by Chen, David S., Escobedo, Eva M., Eastman, Jonathan G., Bloomstein, Joshua D., Taylor, Sandra L., Seibert, J. Anthony

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Transcriptome Analysis of Tumor-Infiltrating Lymphocytes Identifies NK Cell Gene Signatures Associated With Lymphocyte Infiltration and Survival in Soft Tissue Sarcomas by Judge, Sean J, Bloomstein, Joshua D, Sholevar, Cyrus J, Darrow, Morgan A, Stoffel, Kevin M, Vick, Logan V, Dunai, Cordelia, Cruz, Sylvia M, Razmara, Aryana M, Monjazeb, Arta M, Rebhun, Robert B, Murphy, William J, Canter, Robert J

“…Clinical successes using current T-cell based immunotherapies have been limited in soft tissue sarcomas (STS), while pre-clinical studies have shown evidence…”
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Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes by Saiki, Julie P., Cao, Hongbin, Van Wassenhove, Lauren D., Viswanathan, Vignesh, Bloomstein, Joshua, Nambiar, Dhanya K., Mattingly, Aaron J., Jiang, Dadi, Chen, Che-Hong, Stevens, Matthew C., Simmons, Amanda L., Park, Hyun Shin, von Eyben, Rie, Kool, Eric T., Sirjani, Davud, Knox, Sarah M., Le, Quynh Thu, Mochly-Rosen, Daria

“…Xerostomia (dry mouth) is the most common side effect of radiation therapy in patients with head and neck cancer and causes difficulty speaking and swallowing…”
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The role of Glial cell derived neurotrophic factor in head and neck cancer by Cao, Hongbin, He, Qian, Eyben, Rie von, Bloomstein, Joshua, Nambiar, Dhanya K, Viswanathan, Vignesh, Aggarwal, Sonya, Kwok, Shirley, Liang, Rachel, Koong, Amanda Jeanette, Lewis, Jr, James S, Kong, Christina, Xiao, Nan, Le, Quynh-Thu

“…Glial cell-derived neurotrophic factor (GDNF) is reported to promote the survival of neurons and salivary gland regeneration after radiation damage. This study…”
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Validated limited gene predictor for cervical cancer lymph node metastases by Bloomstein, Joshua D., Eyben, Rie von, Chan, Andy, Rankin, Erinn B., Fregoso, Daniel R., Wang-Chiang, Jing, Lee, Lisa, Xie, Liang-Xi, David, Shannon MacLaughlan, Stehr, Henning, Esfahani, Mohammad S., Giaccia, Amato J., Kidd, Elizabeth A.

“…PURPOSERecognizing the prognostic significance of lymph node (LN) involvement for cervical cancer, we aimed to identify genes that are differentially expressed…”
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646 Transcriptome analysis of tumor and matched infiltrating lymphocytes identifies potential new targets for augmenting intra-tumoral NK function in soft tissue sarcomas by Judge, Sean, Bloomstein, Joshua, Cruz, Sylvia, Razmara, Aryana, Sholevar, Cyrus, Canter, Robert

“…BackgroundThe success of current immunotherapies in soft tissue sarcomas (STS) has been limited, although pre-clinical studies have shown evidence of natural…”
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Pneumonia surveillance with culture-independent metatranscriptomics in HIV-positive adults in Uganda: a cross-sectional study by Spottiswoode, Natasha, Bloomstein, Joshua D, Caldera, Saharai, Sessolo, Abdul, McCauley, Kathryn, Byanyima, Patrick, Zawedde, Josephine, Kalantar, Katrina, Kaswabuli, Sylvia, Rutishauser, Rachel L, Lieng, Monica K, Davis, J Lucian, Moore, Julia, Jan, Amanda, Iwai, Shoko, Shenoy, Meera, Sanyu, Ingvar, DeRisi, Joseph L, Lynch, Susan V, Worodria, William, Huang, Laurence, Langelier, Charles R

“…Pneumonia is a leading cause of death worldwide and is a major health-care challenge in people living with HIV. Despite this, the causes of pneumonia in this…”
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Simultaneous treatment of Samter triad and prurigo nodularis with dupilumab by Bloomstein, Joshua D., Hawkes, Jason E.

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Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance by Nambiar, Dhanya K, Aguilera, Todd, Cao, Hongbin, Kwok, Shirley, Kong, Christina, Bloomstein, Joshua, Wang, Zemin, Rangan, Vangipuram S, Jiang, Dadi, von Eyben, Rie, Liang, Rachel, Agarwal, Sonya, Colevas, A Dimitrios, Korman, Alan, Allen, Clint T, Uppaluri, Ravindra, Koong, Albert C, Giaccia, Amato, Le, Quynh Thu

“…Immune checkpoint inhibitors (ICIs), although promising, have variable benefit in head and neck cancer (HNC). We noted that tumor galectin-1 (Gal1) levels were…”
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Chemical Space Mimicry for Drug Discovery by Yuan, William, Jiang, Dadi, Nambiar, Dhanya K, Liew, Lydia P, Hay, Michael P, Bloomstein, Joshua, Lu, Peter, Turner, Brandon, Le, Quynh-Thu, Tibshirani, Robert, Khatri, Purvesh, Moloney, Mark G, Koong, Albert C

“…We describe a new library generation method, Machine-based Identification of Molecules Inside Characterized Space (MIMICS), that generates sets of molecules…”
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Abstract LB-180: Targeting galectin-1 in combination with radiation and immune checkpoint therapy in head and neck cancers by Nambiar, Dhanya K., Aguilera, Todd, Bloomstein, Joshua Daniel, Cao, Hongbin, Koong, Albert, Le, Quynh Thu

“…Head and neck cancers (HNC) development shows significant changes in the immune profile, with lower systemic lymphocyte counts and reduced tumor-infiltrating…”
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Abstract IA-003: Oxygen dependent resistance to PARP inhibitors by Mehibel, Manal, Xu, Jimmy, Li, Grace, Moon, Jung, Thakkar, Kaushik, Diep, Anh, Kim, Ryan, Bloomstein, Joshua, Xiao, Siren, Bacal, Julien, Saldivar, Joshua, Le, Quynh, Cimprich, Karlene, Rankin, Erinn, Giaccia, Amato

“…Severe hypoxia causes resistance to conventional chemotherapy and has been reported to synergize with PARP inhibitors (PARPi) through suppression of homologous…”
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Abstract 4068: Galectin-1 intensifies immunosuppression in head and neck cancer by boosting myeloid-derived suppressive cell (MDSC) expansion by Nambiar, Dhanya K., Aguilera, Todd A., Bloomstein, Joshua Daniel, Jiang, Dadi, Cao, Hongbin, Koong, Albert, Le, Quynh Thu

“…Head and neck squamous cell carcinoma (HNSCC), with more than 450,000 newly diagnosed cases annually, is the 6th most common cancer worldwide. Recent…”
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Microbial dynamics and pulmonary immune responses in COVID-19 secondary bacterial pneumonia by Spottiswoode, Natasha, Tsitsiklis, Alexandra, Chu, Victoria T., Phan, Hoang Van, DeVoe, Catherine, Love, Christina, Ghale, Rajani, Bloomstein, Joshua, Zha, Beth Shoshana, Maguire, Cole P., Glascock, Abigail, Sarma, Aartik, Mourani, Peter M., Kalantar, Katrina L., Detweiler, Angela, Neff, Norma, Haller, Sidney C., DeRisi, Joseph L., Erle, David J., Hendrickson, Carolyn M., Kangelaris, Kirsten N., Krummel, Matthew F., Matthay, Michael A., Woodruff, Prescott G., Calfee, Carolyn S., Langelier, Charles R.

“…Secondary bacterial pneumonia (2°BP) is associated with significant morbidity following respiratory viral infection, yet remains incompletely understood. In a…”
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