Search Results - "Bloomfield, Victor A"

Salt Dependence of the Elasticity and Overstretching Transition of Single DNA Molecules by Wenner, Jay R., Williams, Mark C., Rouzina, Ioulia, Bloomfield, Victor A.

“…As double-stranded DNA is stretched to its B-form contour length, models of polymer elasticity can describe the dramatic increase in measured force. When the…”
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Thermodynamics of Cationic Lipid Binding to DNA and DNA Condensation:  Roles of Electrostatics and Hydrophobicity by Matulis, Daumantas, Rouzina, Ioulia, Bloomfield, Victor A

“…Alkylammonium binding to DNA was studied by isothermal titration calorimetry. Experimental data, obtained as functions of alkyl chain length, salt…”
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Ionic Effects on the Elasticity of Single DNA Molecules by Baumann, Christoph G., Smith, Steven B., Bloomfield, Victor A., Bustamante, Carlos

“…We used a force-measuring laser tweezers apparatus to determine the elastic properties of λ -bacteriophage DNA as a function of ionic strength and in the…”
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Thermodynamics of DNA Interactions from Single Molecule Stretching Experiments by Williams, Mark C, Rouzina, Ioulia, Bloomfield, Victor A

“…On the basis of our analysis of detailed measurements of the dependence of the overstretching transition of double-stranded DNA (dsDNA) on temperature, pH, and…”
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Effect of pH on the Overstretching Transition of Double-Stranded DNA: Evidence of Force-Induced DNA Melting by Williams, Mark C., Wenner, Jay R., Rouzina, Ioulia, Bloomfield, Victor A.

“…When a single molecule of double-stranded DNA is stretched beyond its B-form contour length, the measured force shows a highly cooperative overstretching…”
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Entropy and Heat Capacity of DNA Melting from Temperature Dependence of Single Molecule Stretching by Williams, Mark C., Wenner, Jay R., Rouzina, Ioulia, Bloomfield, Victor A.

“…When a single molecule of double-stranded DNA is stretched beyond its B-form contour length, the measured force shows a highly cooperative overstretching…”
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Stretching of Single Collapsed DNA Molecules by Baumann, Christoph G., Bloomfield, Victor A., Smith, Steven B., Bustamante, Carlos, Wang, Michelle D., Block, Steven M.

“…The elastic response of single plasmid and lambda phage DNA molecules was probed using optical tweezers at concentrations of trivalent cations that provoked…”
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Excluded Volume in Solvation: Sensitivity of Scaled-Particle Theory to Solvent Size and Density by Tang, Karen E.S., Bloomfield, Victor A.

“…Changes in solvent environment greatly affect macromolecular structure and stability. To investigate the role of excluded volume in solvation, scaled-particle…”
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Crowding Effects on EcoRV Kinetics and Binding by Wenner, Jay R., Bloomfield, Victor A.

“…The cytosol of the cell contains high concentrations of small and large macromolecules, but experimental data are often obtained in dilute solutions that do…”
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Force-Induced Melting of the DNA Double Helix 1. Thermodynamic Analysis by Rouzina, Ioulia, Bloomfield, Victor A.

“…The highly cooperative elongation of a single B-DNA molecule to almost twice its contour length upon application of a stretching force is interpreted as…”
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DNA condensation by Bloomfield, Victor A

“…Recent progress in our understanding of DNA condensation includes the observation of the collapse of single DNA molecules, greater insights into the…”
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DNA condensation by multivalent cations by Bloomfield, Victor A.

“…In the presence of multivalent cations, high molecular weight DNA undergoes a dramatic condensation to a compact, usually highly ordered toroidal structure…”
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Force-Induced Melting of the DNA Double Helix. 2. Effect of Solution Conditions by Rouzina, Ioulia, Bloomfield, Victor A.

“…In this paper, we consider the implications of the general theory developed in the accompanying paper, to interpret experiments on DNA overstretching that…”
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Small-angle x-ray scattering of semidilute rodlike DNA solutions: polyelectrolyte behavior by Wang, Lixiao, Bloomfield, Victor A

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Competitive Electrostatic Binding of Charged Ligands to Polyelectrolytes:  Planar and Cylindrical Geometries by Rouzina, Ioulia, Bloomfield, Victor A

“…The strong salt dependence of the binding of multivalent ligands to DNA indicates the predominantly electrostatic nature of that binding. To a good first…”
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Structural basis of polyamine-DNA recognition: spermidine and spermine interactions with genomic B-DNAs of different GC content probed by Raman spectroscopy by Deng, H, Bloomfield, V A, Benevides, J M, Thomas, Jr, G J

“…Four genomic DNAs of differing GC content (Micrococcus luteus, 72% GC; Escherichia coli, 50% GC; calf thymus, 42% GC; Clostridium perfringens, 27% GC) have…”
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Hexamminecobalt(III)-induced condensation of calf thymus DNA: circular dichroism and hydration measurements by Kankia, B I, Buckin, V, Bloomfield, V A

“…The interaction of hexamminecobalt(III), Co(NH(3))(6)(3+), with 160 and 3000-8000 bp length calf thymus DNA has been investigated by circular dichroism,…”
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Mechanism for Nucleic Acid Chaperone Activity of HIV-1 Nucleocapsid Protein Revealed by Single Molecule Stretching by Williams, Mark C., Rouzina, Ioulia, Wenner, Jay R., Gorelick, Robert J., Musier-Forsyth, Karin, Bloomfield, Victor A.

“…The nucleocapsid protein (NC) of HIV type 1 is a nucleic acid chaperone that facilitates the rearrangement of nucleic acids into conformations containing the…”
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Probe Diffusion in Concentrated Polyelectrolyte Solutions:  Effect of Background Interactions on Competition between Electrostatic and Viscous Forces by Jena, Sidhartha S, Bloomfield, Victor A

“…We have used fluorescence recovery after photobleaching (FRAP) to measure the diffusion coefficient D of a small probe protein, green fluorescent protein…”
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Influence of Ligand Spatial Organization on Competitive Electrostatic Binding to DNA by Rouzina, Ioulia, Bloomfield, Victor A

“…The influence of ligand size on electrostatic binding to DNA in a background of competing counterions is analyzed with the planar Poisson−Boltzmann (P−B)…”
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