Search Results - "Bloomfield, Susan"

Inflammation‐induced lymphatic architecture and bone turnover changes are ameliorated by irisin treatment in chronic inflammatory bowel disease by Narayanan, S. Anand, Metzger, Corinne E., Bloomfield, Susan A., Zawieja, David C.

“…ABSTRACT Inflammatory bowel disease (IBD) is a chronic disease with gastrointestinal dysfunction as well as comorbidities such as inflammation‐induced bone…”
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Inflammatory Bowel Disease in a Rodent Model Alters Osteocyte Protein Levels Controlling Bone Turnover by Metzger, Corinne E, Narayanan, Anand, Zawieja, David C, Bloomfield, Susan A

“…ABSTRACT Bone loss is a common comorbidity of inflammatory bowel disease (IBD), leading to elevated fracture risk in these patients. Inflammatory factors…”
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Space Environmental Factor Impacts upon Murine Colon Microbiota and Mucosal Homeostasis by Ritchie, Lauren E, Taddeo, Stella S, Weeks, Brad R, Lima, Florence, Bloomfield, Susan A, Azcarate-Peril, M Andrea, Zwart, Sara R, Smith, Scott M, Turner, Nancy D

“…Astronaut intestinal health may be impacted by microgravity, radiation, and diet. The aim of this study was to characterize how high and low linear energy…”
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Osteocytes reflect a pro-inflammatory state following spinal cord injury in a rodent model by Metzger, Corinne E., Gong, Sammy, Aceves, Miriam, Bloomfield, Susan A., Hook, Michelle A.

“…Profound bone loss occurs following spinal cord injury (SCI) resulting in a high incidence of fractures. While likely caused in part by loss of weight-bearing,…”
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Beta-1 adrenergic agonist treatment mitigates negative changes in cancellous bone microarchitecture and inhibits osteocyte apoptosis during disuse by Swift, Joshua M, Swift, Sibyl N, Allen, Matthew R, Bloomfield, Susan A

“…The sympathetic nervous system (SNS) plays an important role in mediating bone remodeling. However, the exact role that beta-1 adrenergic receptors (beta1AR)…”
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A rodent model of human dose-equivalent progestin-only implantable contraception by Allaway, Heather C M, Pierson, Roger A, Invik, Jesse, Bloomfield, Susan A

“…Long-acting, reversible contraceptives (LARC; progestin only) are an increasingly common hormonal contraceptive choice in reproductive aged women looking to…”
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DSS-induced colitis produces inflammation-induced bone loss while irisin treatment mitigates the inflammatory state in both gut and bone by Metzger, Corinne E., Narayanan, S. Anand, Elizondo, Jon P., Carter, Anne Michal, Zawieja, David C., Hogan, Harry A., Bloomfield, Susan A.

“…Chronic pediatric inflammatory bowel disease (IBD) leads to lack of bone accrual, bone loss, and increased fractures. Presently there is no cure, and many IBD…”
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Rapid Transition from a High-Fat, High-Fructose to a Low-Fat, Low-Fructose Diet Reverses Gains in Bone Mass and Strength by Little-Letsinger, Sarah E., Letsinger, Ayland C., Elizondo, Jon P., Breidenbach, Brianne M., Hogan, Harry A., Lightfoot, J. Timothy, Bloomfield, Susan A.

“…Obesity is thought to negatively impact bone quality and strength, despite improving bone mineral density. We hypothesized that 1) continuous consumption of a…”
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Biomechanical Aspects of the Muscle-Bone Interaction by Avin, Keith G., Bloomfield, Susan A., Gross, Ted S., Warden, Stuart J.

“…There is growing interest in the interaction between skeletal muscle and bone, particularly at the genetic and molecular levels. However, the genetic and…”
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Omega-3 fatty acid modulation of serum and osteocyte tumor necrosis factor-α in adult mice exposed to ionizing radiation by Little-Letsinger, Sarah E, Turner, Nancy D, Ford, John R, Suva, Larry J, Bloomfield, Susan A

“…Chronic inflammation leads to bone loss and fragility. Proinflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) consistently promote bone…”
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Blocking β-adrenergic signaling attenuates reductions in circulating leptin, cancellous bone mass, and marrow adiposity seen with dietary energy restriction by Baek, Kyunghwa, Bloomfield, Susan A

“…We tested whether β-adrenergic blockade attenuates bone loss and increased marrow adiposity during energy restriction (ER) and whether such an effect is…”
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A moderately elevated soy protein diet mitigates inflammatory changes in gut and in bone turnover during chronic TNBS-induced inflammatory bowel disease by Metzger, Corinne E, Narayanan, S Anand, Zawieja, David C, Bloomfield, Susan A

“…Inflammatory bowel disease is a condition that leads to gut pathologies such as abnormal lymphatic architecture, as well as to systemic comorbidities such as…”
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Contemporary Issue: Health and Safety of Female Wrestlers by Jagim, Andrew R, Moschelli, Jill S, Woodroffe, Lisa M, Horswill, Craig A, Bloomfield, Susan A, Oppliger, Robert A

“…Female wrestling has grown exponentially over the past decade. Within the United States, 46 states now recognize female high school wrestling, and 153 colleges…”
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Exercise training modifies the bone and endocrine response to graded reductions in energy availability in skeletally mature female rodents by Bloomfield, Susan A, Swift, Sibyl N, Metzger, Corinne E, Baek, Kyunghwa, De Souza, Mary Jane, Lenfest, Scott, Shirazi-Fard, Yasaman, Hogan, Harry A

“…Reductions in energy availability leading to weight loss can induce loss of bone and impact important endocrine regulators of bone integrity. We sought to…”
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Discordant recovery of bone mass and mechanical properties during prolonged recovery from disuse by Shirazi-Fard, Yasaman, Kupke, Joshua S, Bloomfield, Susan A, Hogan, Harry A

“…Abstract Profound bone loss at weight bearing sites is a primary effect of long-duration spaceflight. Moreover, a significant increase in estimated fracture…”
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Exposure to Low-Dose X-Ray Radiation Alters Bone Progenitor Cells and Bone Microarchitecture by Lima, Florence, Swift, Joshua M., Greene, Elisabeth S., Allen, Matthew R., Cunningham, David A., Braby, Leslie A., Bloomfield, Susan A.

“…Exposure to high-dose ionizing radiation during medical treatment exerts well-documented deleterious effects on bone health, reducing bone density and…”
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Hindlimb unloading causes regional loading-dependent changes in osteocyte inflammatory cytokines that are modulated by exogenous irisin treatment by Metzger, Corinne E., Anand Narayanan, S., Phan, Peter H., Bloomfield, Susan A.

“…Disuse-induced bone loss is characterized by alterations in bone turnover. Accruing evidence suggests that osteocytes respond to inflammation and express…”
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Towards human exploration of space: the THESEUS review series on muscle and bone research priorities by Lang, Thomas, Van Loon, Jack J.W.A., Bloomfield, Susan, Vico, Laurence, Chopard, Angele, Rittweger, Joern, Kyparos, Antonios, Blottner, Dieter, Vuori, Ilkka, Gerzer, Rupert, Cavanagh, Peter R.

“…Without effective countermeasures, the musculoskeletal system is altered by the microgravity environment of long-duration spaceflight, resulting in atrophy of…”
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Oral Estradiol Impact on Mitigating Unloading-Induced Bone Loss in Ovary-Intact Rats by Mantri, Anita V, Allaway, Heather C M, Brezicha, Jessica E, Hogan, Harry A, Bloomfield, Susan A

“…The impact of the spaceflight environment on endogenous estrogen production in female crewmembers and the resulting impact on other adaptations, like bone…”
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β‐Adrenergic Blockade and Leptin Replacement Effectively Mitigate Disuse Bone Loss by Baek, Kyunghwa, Bloomfield, Susan A

“…Our objective was to test effects of β‐adrenergic blockade on hindlimb unloading (HU)‐induced bone loss and serum leptin and to compare these responses with…”
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