Search Results - "Bloom, S"
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1
The regulation of food intake by the gut-brain axis: implications for obesity
Published in International Journal of Obesity (01-05-2013)“…Our understanding of the regulation of appetite has improved considerably over the last few decades. Recent work, stimulated by efforts aimed at curbing the…”
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2
An empirical relation between sodium absorption and dust extinction
Published in Monthly notices of the Royal Astronomical Society (21-10-2012)“…ABSTRACT Dust extinction and reddening are ubiquitous in astronomical observations and are often a major source of systematic uncertainty. We present here a…”
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3
Centromeric Heterochromatin: The Primordial Segregation Machine
Published in Annual review of genetics (01-01-2014)“…Centromeres are specialized domains of heterochromatin that provide the foundation for the kinetochore. Centromeric heterochromatin is characterized by…”
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4
Genetics of trans -regulatory variation in gene expression
Published in eLife (17-07-2018)“…Heritable variation in gene expression forms a crucial bridge between genomic variation and the biology of many traits. However, most expression quantitative…”
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5
The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents
Published in International Journal of Obesity (01-03-2015)“…Background and Objectives: The gut hormones peptide YY (PYY) and glucagon-like peptide 1 (GLP-1) acutely suppress appetite. The short chain fatty acid (SCFA)…”
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6
Minireview: Glucagon in Stress and Energy Homeostasis
Published in Endocrinology (Philadelphia) (01-03-2012)“…Glucagon is traditionally thought of as an antihypoglycemic hormone, for example in response to starvation. However, it actually increases energy expenditure…”
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7
Reversible disorder-order transitions in atomic crystal nucleation
Published in Science (American Association for the Advancement of Science) (29-01-2021)“…Nucleation in atomic crystallization remains poorly understood, despite advances in classical nucleation theory. The nucleation process has been described to…”
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8
Portal hypertension: pathophysiology, diagnosis and management
Published in Internal medicine journal (01-01-2015)“…Portal hypertension is an important complication of liver disease. As a result of elevated pressures within the portal vein several complications can arise,…”
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9
CRISPR-directed mitotic recombination enables genetic mapping without crosses
Published in Science (American Association for the Advancement of Science) (27-05-2016)“…Linkage and association studies have mapped thousands of genomic regions that contribute to phenotypic variation, but narrowing these regions to the underlying…”
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10
Problem or solution: The strange story of glucagon
Published in Peptides (New York, N.Y. : 1980) (01-02-2018)“…•Hyperglucagonaemia is seen in all forms of diabetes including type 2 diabetes and alloxan-induced pancreatic destruction.•Agents that block activity at the…”
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11
Finding the sources of missing heritability in a yeast cross
Published in Nature (London) (14-02-2013)“…In a cross between two yeast strains, detected loci are found to explain nearly the entire additive contribution to heritable variation for a number of…”
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12
Genetic interactions contribute less than additive effects to quantitative trait variation in yeast
Published in Nature communications (05-11-2015)“…Genetic mapping studies of quantitative traits typically focus on detecting loci that contribute additively to trait variation. Genetic interactions are often…”
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13
Tau: The Center of a Signaling Nexus in Alzheimer's Disease
Published in Frontiers in neuroscience (09-02-2016)“…Tau is a microtubule-associated protein whose misfolding, hyper-phosphorylation, loss of normal function and toxic gain of function are linked to several…”
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14
GROWTH on S190814bv: Deep Synoptic Limits on the Optical/Near-infrared Counterpart to a Neutron Star-Black Hole Merger
Published in The Astrophysical journal (20-02-2020)“…On 2019 August 14, the Advanced LIGO and Virgo interferometers detected the high-significance gravitational wave (GW) signal S190814bv. The GW data indicated…”
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15
Thyroid Function and Perfluoroalkyl Acids in Children Living Near a Chemical Plant
Published in Environmental health perspectives (01-07-2012)“…Background: Animal studies suggest that some perfluoroalkyl acids (PFAAs), including perfluorooctanoate (PFOA), perfluorooctane sulfonate (PFOS), and…”
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16
Kilonova Luminosity Function Constraints Based on Zwicky Transient Facility Searches for 13 Neutron Star Merger Triggers during O3
Published in The Astrophysical journal (01-12-2020)“…Abstract We present a systematic search for optical counterparts to 13 gravitational wave (GW) triggers involving at least one neutron star during LIGO/Virgo’s…”
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17
Point centromeres contain more than a single centromere-specific Cse4 (CENP-A) nucleosome
Published in The Journal of cell biology (14-11-2011)“…Cse4 is the budding yeast homologue of CENP-A, a modified histone H3 that specifies the base of kinetochores in all eukaryotes. Budding yeast is unique in…”
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18
Using machine learning for discovery in synoptic survey imaging data
Published in Monthly notices of the Royal Astronomical Society (21-10-2013)“…Modern time-domain surveys continuously monitor large swaths of the sky to look for astronomical variability. Astrophysical discovery in such data sets is…”
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The Broad Absorption Line Tidal Disruption Event iPTF15af: Optical and Ultraviolet Evolution
Published in The Astrophysical journal (01-03-2019)“…We present multiwavelength observations of the tidal disruption event (TDE) iPTF15af, discovered by the intermediate Palomar Transient Factory survey at…”
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20
Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast
Published in Nature genetics (01-04-2017)“…Örjan Carlborg and colleagues analyze genotype and phenotype data from 4,390 yeast segregants from a cross between laboratory and vineyard strains to estimate…”
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