Search Results - "Bloom, Floyd"

Recent research on Gulf War illness and other health problems in veterans of the 1991 Gulf War: Effects of toxicant exposures during deployment by White, Roberta F., Steele, Lea, O'Callaghan, James P., Sullivan, Kimberly, Binns, James H., Golomb, Beatrice A., Bloom, Floyd E., Bunker, James A., Crawford, Fiona, Graves, Joel C., Hardie, Anthony, Klimas, Nancy, Knox, Marguerite, Meggs, William J., Melling, Jack, Philbert, Martin A., Grashow, Rachel

“…Veterans of Operation Desert Storm/Desert Shield − the 1991 Gulf War (GW) − are a unique population who returned from theater with multiple health complaints…”
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Early-Onset Behavioral and Synaptic Deficits in a Mouse Model of Alzheimer's Disease by Jacobsen, J. Steven, Wu, Chi-Cheng, Redwine, Jeffrey M., Comery, Thomas A., Arias, Robert, Bowlby, Mark, Martone, Robert, Morrison, John H., Pangalos, Menelas N., Reinhart, Peter H., Bloom, Floyd E.

“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder for which numerous mouse models have been generated. In both AD patients and mouse models,…”
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Distribution of histone deacetylases 1-11 in the rat brain by Broide, Ron S, Redwine, Jeff M, Aftahi, Najla, Young, Warren, Bloom, Floyd E, Winrow, Christopher J

“…Although protein phosphorylation has been characterized more extensively, modulation of the acetylation state of signaling molecules is now being recognized as…”
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Peripheral reduction of β-amyloid is sufficient to reduce brain β-amyloid: Implications for Alzheimer's disease by Sutcliffe, J. Gregor, Hedlund, Peter B., Thomas, Elizabeth A., Bloom, Floyd E., Hilbush, Brian S.

“…Three loci that modify β‐amyloid (Aβ) accumulation and deposition in the brains of a mouse model of Alzheimer's disease have been previously described. One…”
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Mentored and inspired by Mimo: A tribute to Erminio Costa by Bloom, Floyd E.

“…Throughout his long productive scientific career, Erminio Costa demonstrated several scholarly traits that illustrate a pattern for paths of successful…”
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The catecholamine neuron: Historical and future perspectives by Bloom, Floyd E

“…My goals for this perspective are to enumerate what I consider to have been the major discoveries in the investigations of the central catecholamine neuron…”
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Neuroscience of Addiction by Koob, George F, Sanna, Pietro Paolo, Bloom, Floyd E

“…Human addictions are chronically relapsing disorders characterized by compulsive drug taking, an inability to limit the intake of drugs, and the emergence of a…”
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Adult Mouse Brain Gene Expression Patterns Bear an Embryologic Imprint by Zapala, Matthew A., Hovatta, Iiris, Ellison, Julie A., Wodicka, Lisa, Del Rio, Jo A., Tennant, Richard, Tynan, Wendy, Broide, Ron S., Helton, Rob, Stoveken, Barbara S., Winrow, Christopher, Lockhart, Daniel J., Reilly, John F., Young, Warren G., Bloom, Floyd E., Lockhart, David J., Barlow, Carrolee

“…The current model to explain the organization of the mammalian nervous system is based on studies of anatomy, embryology, and evolution. To further investigate…”
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Commentary: Physician-Scientist's Frustrations Fester by Bloom, Floyd E

“…A growing problem of major proportions had been confronting biomedical scientists for many decades. Until solved, this long-neglected problem, the abject…”
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Dentate Gyrus Volume Is Reduced before Onset of Plaque Formation in PDAPP Mice: A Magnetic Resonance Microscopy and Stereologic Analysis by Redwine, Jeffrey M., Kosofsky, Barry, Jacobs, Russell E., Games, Dora, Reilly, John F., Morrison, John H., Young, Warren G., Bloom, Floyd E.

“…High-resolution magnetic resonance microscopy (MRM) was used to determine regional brain volumetric changes in a mouse model of Alzheimer's disease. These…”
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Phosphatidylinositol 3-Kinase Is Required for the Expression But Not for the Induction or the Maintenance of Long-Term Potentiation in the Hippocampal CA1 Region by Sanna, Pietro Paolo, Cammalleri, Maurizio, Berton, Fulvia, Simpson, Cindy, Lutjens, Robert, Bloom, Floyd E, Francesconi, Walter

“…Several signal transduction pathways have been implicated in the induction of long-term potentiation (LTP), yet the signal transduction mechanisms behind the…”
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The 5-HT3 Receptor Is Present in Different Subpopulations of GABAergic Neurons in the Rat Telencephalon by Morales, Marisela, Bloom, Floyd E

“…The type 3 serotonin receptor (5-HT3R) is a ligand-gated ion channel whose presence in the CNS has been established by radioligand binding, in situ…”
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Amyloid Deposition in the Hippocampus and Entorhinal Cortex: Quantitative Analysis of a Transgenic Mouse Model by Reilly, John F., Games, Dora, Rydel, Russell E., Freedman, Stephen, Schenk, Dale, Young, Warren G., Morrison, John H., Bloom, Floyd E.

“…Various transgenic mouse models of Alzheimer's disease (AD) have been developed that overexpress mutant forms of amyloid precursor protein in an effort to…”
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Science as a Way of Life: Perplexities of a Physician-Scientist by Bloom, Floyd E.

“…In this essay adapted from his Presidential Address to the AAAS annual meeting, Floyd Bloom makes the case that today's profound advances in biomedical…”
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Child Development and Neuroscience by Nelson, Charles A., Bloom, Floyd E.

“…Although developmental psychology and developmental neuroscience share interests in common problems (e.g., the nature of thought, emotion, consciousness),…”
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Selective Vulnerability of Dentate Granule Cells Prior to Amyloid Deposition in PDAPP Mice: Digital Morphometric Analyses by Wu, Chi-Cheng, Chawla, Faisal, Games, Dora, Rydel, Russell E., Freedman, Stephen, Schenk, Dale, Young, Warren G., Morrison, John H., Bloom, Floyd E.

“…Increasing evidence from mouse models of Alzheimer's disease shows that overexpression of a mutant form of the amyloid precursor protein (APP) and its product,…”
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Stress, Coping, and Disease by Bloom, Floyd E

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Ethanol Self-Administration Restores Withdrawal-Associated Deficiencies in Accumbal Dopamine and 5-Hydroxytryptamine Release in Dependent Rats by Weiss, Friedbert, Parsons, Loren H, Schulteis, Gery, Hyytia, Petri, Lorang, Marge T, Bloom, Floyd E, Koob, George F

“…Basal forebrain dopamine (DA) and 5-HT neurotransmission has been implicated in the mediation of the acute reinforcing actions of ethanol. Neuroadaptation…”
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An integrative, multidisciplinary approach to the study of brain-behavior relations in the context of typical and atypical development by Nelson, Charles A, Bloom, Floyd E, Cameron, Judy L, Amaral, David, Dahl, Ronald E, Pine, Daniel

“…The study of brain development and that of behavioral development have historically proceeded independently of one another. This is an unfortunate set of…”
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Meta-Analysis of P300 Amplitude From Males at Risk for Alcoholism by Polich, John, Pollock, Vicki E, Bloom, Floyd E

“…The P3(00) event-related brain potential (ERP) is used to study the development of alcoholism by comparing males who have a positive family history of…”
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