Search Results - "Blood research"

Current status of the diagnosis and treatment of hemophagocytic lymphohistiocytosis in adults by Kim, Yu Ri, Kim, Dae-Young

“…Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of defective apoptosis, a disruption of the regulatory pathway that terminates immune and inflammatory…”
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FLT3 mutations in acute myeloid leukemia: a review focusing on clinically applicable drugs by Ahn, Jae-Sook, Kim, Hyeoung-Joon

“…FMS-like tyrosine kinase 3 ( ) mutations, the most frequently detected genetic aberrations in patients with acute myeloid leukemia (AML), are identified in…”
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Classification of acute myeloid leukemia by Hwang, Sang Mee

“…The World Health Organization (WHO) Classification of Tumors of Hematopoietic and Lymphoid Tissues was revised in 2017 on the basis of recent high-throughput…”
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Mesenchymal stem cells in acute myeloid leukemia: a focus on mechanisms involved and therapeutic concepts by Fathi, Ezzatollah, Sanaat, Zohreh, Farahzadi, Raheleh

“…Drug resistance in cancer, especially in leukemia, creates a dilemma in treatment planning. Consequently, studies related to the mechanisms underlying drug…”
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The role of next-generation sequencing in hematologic malignancies by Cho, Young-Uk

“…Next-generation sequencing (NGS) allows high-throughput detection of molecular changes in tumors. Over the past 15 years, NGS has rapidly evolved from a…”
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Characteristics of DNMT3A mutations in acute myeloid leukemia by Park, Dong Jin, Kwon, Ahlm, Cho, Byung-Sik, Kim, Hee-Je, Hwang, Kyung-Ah, Kim, Myungshin, Kim, Yonggoo

“…mutations occur in approximately 20% of AML cases and are associated with changes in DNA methylation. plays an important role in the regulation of…”
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A narrative review on adverse effects of dasatinib with a focus on pharmacotherapy of dasatinib-induced pulmonary toxicities by Nekoukar, Zahra, Moghimi, Minoo, Salehifar, Ebrahim

“…Chronic myeloid leukemia (CML), a myeloproliferative disorder caused by the over activity of BCR-ABL1 (breakpoint cluster region-Abelson), has been…”
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A general view of CD33 + leukemic stem cells and CAR-T cells as interesting targets in acute myeloblatsic leukemia therapy by Fathi, Ezzatollah, Farahzadi, Raheleh, Sheervalilou, Roghayeh, Sanaat, Zohreh, Vietor, Ilja

“…Acute myeloblastic leukemia (AML) is the most frequent acute leukemia in adulthood with very poor overall survival rates. In the past few decades, significant…”
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Abnormal frequency of the memory B cell subsets and plasmablasts in patients with congenital severe hemophilia A: correlation with “Inhibitor” formation by Zekavat, Omid Reza, Movahednezhad, Yasaman, Shahsavani, Amin, Haghpanah, Sezaneh, Shokrgozar, Negin, Golmoghaddam, Hossein, Kalani, Mehdi, Bordbar, Mohammad Reza, Arandi, Nargess

“…Background Development of antibodies against infused Factor VIII (FVIII) or "inhibitors" represents a major challenge following FVIII replacement therapy in…”
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Treatment of relapsed and refractory multiple myeloma by Lee, Ji Hyun, Kim, Sung-Hyun

“…The therapeutic strategy for relapsed and refractory multiple myeloma (RRMM) integrates a holistic approach regarding patient, disease, and drug-related…”
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Molecular basis and diagnosis of thalassemia by Lee, Jee-Soo, Cho, Sung Im, Park, Sung Sup, Seong, Moon-Woo

“…Thalassemia is characterized by the impaired synthesis of globin chains due to disease-causing variants in α- or β-globin genes. In this review, we provide an…”
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Plasmacytoid dendritic cell neoplasms by Lee, Yoo Jin, Kim, Youjin, Park, Sang Hyuk, Jo, Jae-Cheol

“…Plasmacytoid dendritic cells (pDCs) are type I interferon-producing cells that modulate immune responses. There are two types of pDC neoplasms: 1) mature pDC…”
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Asciminib: the first-in-class allosteric inhibitor of BCR::ABL1 kinase by Choi, Eun-Ji

“…The prognosis of patients with chronic phase (CP) chronic myeloid leukemia (CML) has significantly improved due to the development of potent BCR::ABL1 tyrosine…”
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Hepatitis B surface antigen reverse seroconversion after hematopoietic stem cell transplantation according to the baseline serological marker levels and vaccination status: a single-center database analysis by Kang, Soo Young, Ko, Heejoo, Lee, Raeseok, Park, Sung-Soo, Han, Seunghoon

“…Purpose Hepatitis B is a major prognostic factor after hematopoietic stem cell transplantation (HSCT). Currently, no consensus exists regarding the management…”
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Absence of canonical mutations in pediatric essential thrombocytosis: a case series by Lee, Jae Wook, Jo, Suejung, Yoo, Jae Won, Kim, Seongkoo, Chung, Nack-Gyun, Cho, Bin

“…Essential thrombocytosis (ET) is a rare myeloproliferative disease in children, and there are few standard management guidelines. We herein report a case…”
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Gaucher or pseudo-Gaucher cells by Kaur, Gurpreet, Ahuja, Ankur, Vishwananthan, Ganesh Kumar, Sen, Arijit

“…KCI Citation Count: 0…”
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Real-world incidence and risk factors of bortezomib-related cardiovascular adverse events in patients with multiple myeloma by Jang, Bitna, Jeong, Jonghyun, Heo, Kyu-Nam, Koh, Youngil, Lee, Ju‑Yeun

“…Background Although most studies on the cardiovascular toxicity of proteasome inhibitors have focused on carfilzomib, the risk of cardiotoxicity associated…”
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Real-world insights into the management of hemophilia A in Italy: treatment patterns and healthcare resource utilization by Perrone, Valentina, Leogrande, Melania, Cappuccilli, Maria, Esposti, Luca Degli

“…Purpose This real-world analysis described the Hemophilia A (HA) population in Italy, evaluating drug utilization and consumption of factor VIII (FVIII)…”
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Clinical data on treatment regimen and use of medication among patients with hemophilia B in Korea by Park, Young Shil, Park, Ji Kyoung, Park, Jeong A, Baek, Hee Jo, Lee, Jae Hee, You, Chur Woo, Lyu, Chuhl Joo, Choi, Eun Jin

“…Background To investigate the clinical treatment status, such as treatment regimen, bleeding events, and drug dose, in patients with hemophilia B in South…”
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Comparable outcomes with low-dose and standard-dose horse anti-thymocyte globulin in the treatment of severe aplastic anemia by Jain, Arihant, Jandial, Aditya, Mani, Thenmozhi, Kishore, Kamal, Singh, Charanpreet, Lad, Deepesh, Prakash, Gaurav, Khadwal, Alka, Das, Reena, Varma, Neelam, Varma, Subhash, Malhotra, Pankaj

“…Background The standard dose (SD) of horse anti-thymocyte globulin (hATG) ATGAM (Pfizer, USA) or its biosimilar thymogam (Bharat Serum, India) for the…”
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