Search Results - "Blom, Elin S."

Increased mRNA Levels of TCF7L2 and MYC of the Wnt Pathway in Tg-ArcSwe Mice and Alzheimer's Disease Brain by Wang, Yijing, Blom, Elin S., Skoglund, Lena, Hansson, Anita C., Ubaldi, Massimo, Lourdusamy, Anbarasu, Sommer, Wolfgang H., Mielke, Matthew, Hyman, Bradley T., Heilig, Markus, Lannfelt, Lars, Nilsson, Lars N. G., Ingelsson, Martin

“…Several components in the Wnt pathway, including β-catenin and glycogen synthase kinase 3 beta, have been implied in AD pathogenesis. Here, mRNA brain levels…”
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Further analysis of previously implicated linkage regions for Alzheimer's disease in affected relative pairs by Blom, Elin S, Giedraitis, Vilmantas, Arepalli, Sampath, Hamshere, Marian L, Adighibe, Omanma, Goate, Alison, Williams, Julie, Lannfelt, Lars, Hardy, John, Vrièze, Fabienne Wavrant-De, Glaser, Anna

“…Genome-wide linkage studies for Alzheimer's disease have implicated several chromosomal regions as potential loci for susceptibility genes. In the present…”
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Low prevalence of APP duplications in Swedish and Finnish patients with early-onset Alzheimer's disease by BLOM, Elin S, VISWANATHAN, Jayashree, KILANDER, Lena, HELISALMI, Seppo, SOININEN, Hilkka, LANNFELT, Lars, INGELSSON, Martin, GLASER, Anna, HILTUNEN, Mikko

“…Familial early-onset Alzheimer's disease with cerebral amyloid angiopathy (EOAD/CAA) was recently associated with duplications of the gene for the amyloid-beta…”
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Novel Progranulin Mutation Detected in 2 Patients With FTLD by SKOGLUND, Lena, MATSUI, Toshifumi, GLASER, Anna, FREEMAN, Stefanie H, WALLIN, Anders, BLOM, Elin S, FROSCH, Matthew P, GROWDON, John H, HYMAN, Bradley T, LANNFELT, Lars, INGELSSON, Martin

“…Frontotemporal lobar degeneration (FTLD) with ubiquitin-positive, tau-negative inclusions, and linkage to chromosome 17 was recently found to be caused by…”
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Frontotemporal dementia in a large Swedish family is caused by a progranulin null mutation by Skoglund, Lena, Brundin, RoseMarie, Olofsson, Tommie, Kalimo, Hannu, Ingvast, Sofie, Blom, Elin S., Giedraitis, Vilmantas, Ingelsson, Martin, Lannfelt, Lars, Basun, Hans, Glaser, Anna

“…Mutations in the progranulin ( PGRN ) gene have recently been identified in families with frontotemporal lobar degeneration and ubiquitin-positive brain…”
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Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13? by Blom, Elin S., Holmans, Peter, Arepalli, Sampath, Adighibe, Omanma, Hamshere, Marian L., Gatz, Margaret, Pedersen, Nancy L., Bergem, A. L. Mina, Owen, Michael J., Hollingworth, Paul, Goate, Alison, Williams, Julie, Lannfelt, Lars, Hardy, John, Wavrant-De Vrièze, Fabienne, Glaser, Anna

“…We have studied the impact of the apolipoprotein E gene (APOE) on the chromosome 19 linkage peak from an analysis of sib‐pairs affected by Alzheimer's disease…”
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Rapid progression from mild cognitive impairment to Alzheimer's disease in subjects with elevated levels of tau in cerebrospinal fluid and the APOE epsilon4/epsilon4 genotype by Blom, Elin S, Giedraitis, Vilmantas, Zetterberg, Henrik, Fukumoto, Hiroaki, Blennow, Kaj, Hyman, Bradley T, Irizarry, Michael C, Wahlund, Lars-Olof, Lannfelt, Lars, Ingelsson, Martin

“…Increased cerebrospinal fluid (CSF) tau, decreased CSF amyloid-beta42 (Abeta42) and the apolipoprotein E gene (APOE) epsilon4 allele predict progression from…”
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P3-205: Upregulation of genes in the Wnt pathway in tg-ArcSwe mice and Alzheimer's disease brain by Blom, Elin S, Wang, Yijing, Hansson, Anita, Sommer, Wolfgang, Hyman, Bradley T, Heilig, Markus, Lannfelt, Lars, Nisson, Lars N.G, Ingelsson, Martin

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P1-030: Analysis of gene expression in brains of tg-APP-ArcSwe mice, a model for Alzheimer’s disease by Blom, Elin S., Sommer, Wolfgang H., Hansson, Anita C., Heilig, Markus, Ubaldi, Massimo, Lourdusamy, Anbarasu A., Lannfelt, Lars, Ingelsson, Martin, Nilsson, Lars N.G.

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