Search Results - "Blok, Anneloes J"

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    β-Lactamase of Mycobacterium tuberculosis Shows Dynamics in the Active Site That Increase upon Inhibitor Binding by Elings, Wouter, Gaur, Anamika, Blok, Anneloes J, Timmer, Monika, van Ingen, Hugo, Ubbink, Marcellus

    Published in Antimicrobial agents and chemotherapy (21-02-2020)
    “…The β-lactamase BlaC is a broad-spectrum β-lactamase that can convert a range of β-lactam antibiotics. Enzymes with low specificity are expected to exhibit…”
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    Journal Article
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    Two β-Lactamase Variants with Reduced Clavulanic Acid Inhibition Display Different Millisecond Dynamics by Elings, Wouter, Chikunova, Aleksandra, van Zanten, Danny B, Drenth, Ralphe, Ahmad, Misbha Ud Din, Blok, Anneloes J, Timmer, Monika, Perrakis, Anastassis, Ubbink, Marcellus

    Published in Antimicrobial agents and chemotherapy (16-07-2021)
    “…The β-lactamase of Mycobacterium tuberculosis, BlaC, is susceptible to inhibition by clavulanic acid. The ability of this enzyme to escape inhibition through…”
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    Journal Article
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    Phosphate Promotes the Recovery of Mycobacterium tuberculosis β‑Lactamase from Clavulanic Acid Inhibition by Elings, Wouter, Tassoni, Raffaella, van der Schoot, Steven A, Luu, Wendy, Kynast, Josef P, Dai, Lin, Blok, Anneloes J, Timmer, Monika, Florea, Bogdan I, Pannu, Navraj S, Ubbink, Marcellus

    Published in Biochemistry (Easton) (28-11-2017)
    “…The rise of multi- and even totally antibiotic resistant forms of Mycobacterium tuberculosis underlines the need for new antibiotics. The pathogen is resistant…”
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    Journal Article
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    Redox-State-Dependent Complex Formation between Pseudoazurin and Nitrite Reductase by Impagliazzo, Antonietta, Blok, Anneloes J, Cliff, Matthew J, Ladbury, John E, Ubbink, Marcellus

    Published in Journal of the American Chemical Society (10-01-2007)
    “…Bacterial copper-containing nitrite reductase catalyzes the reduction of nitrite to nitric oxide as part of the denitrification process. Pseudoazurin interacts…”
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    Journal Article