Search Results - "Blok, Anneloes J"
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HI-NESS: a family of genetically encoded DNA labels based on a bacterial nucleoid-associated protein
Published in Nucleic acids research (25-01-2022)“…Abstract The interplay between three-dimensional chromosome organisation and genomic processes such as replication and transcription necessitates in vivo…”
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β-Lactamase of Mycobacterium tuberculosis Shows Dynamics in the Active Site That Increase upon Inhibitor Binding
Published in Antimicrobial agents and chemotherapy (21-02-2020)“…The β-lactamase BlaC is a broad-spectrum β-lactamase that can convert a range of β-lactam antibiotics. Enzymes with low specificity are expected to exhibit…”
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Two β-Lactamase Variants with Reduced Clavulanic Acid Inhibition Display Different Millisecond Dynamics
Published in Antimicrobial agents and chemotherapy (16-07-2021)“…The β-lactamase of Mycobacterium tuberculosis, BlaC, is susceptible to inhibition by clavulanic acid. The ability of this enzyme to escape inhibition through…”
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Phosphate Promotes the Recovery of Mycobacterium tuberculosis β‑Lactamase from Clavulanic Acid Inhibition
Published in Biochemistry (Easton) (28-11-2017)“…The rise of multi- and even totally antibiotic resistant forms of Mycobacterium tuberculosis underlines the need for new antibiotics. The pathogen is resistant…”
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Redox-State-Dependent Complex Formation between Pseudoazurin and Nitrite Reductase
Published in Journal of the American Chemical Society (10-01-2007)“…Bacterial copper-containing nitrite reductase catalyzes the reduction of nitrite to nitric oxide as part of the denitrification process. Pseudoazurin interacts…”
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