Search Results - "Blohm‐Mangone, Karen A."

Polyamine transport is mediated by both endocytic and solute carrier transport mechanisms in the gastrointestinal tract by Uemura, Takeshi, Stringer, David E, Blohm-Mangone, Karen A, Gerner, Eugene W

“…The polyamines spermidine and spermine, and their precursor putrescine, are required for cell growth and cellular functions. The high levels of tissue…”
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The role of NO synthases in arginine-dependent small intestinal and colonic carcinogenesis by Yerushalmi, Hagit F., Besselsen, David G., Ignatenko, Natalia A., Blohm-Mangone, Karen A., Padilla-Torres, Jose L., Stringer, David E., Cui, Haiyan, Holubec, Hana, Payne, Claire M., Gerner, Eugene W.

“…Arginine is catabolized by NOS2 and other nitric oxide synthases to form nitric oxide. We evaluated the roles of dietary arginine and Nos2 in Apc‐dependent…”
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Combination Chemoprevention of Intestinal Carcinogenesis in a Murine Model of Familial Adenomatous Polyposis by Ignatenko, Natalia A, Besselsen, David G, Stringer, David E, Blohm-Mangone, Karen A, Cui, Haiyan, Gerner, Eugene W

“…Familial adenomatous polyposis (FAP) is an autosomal dominantly inherited syndrome in humans. The Apc(Min/+) mouse, which expresses a mutant homolog of the…”
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Role of polyamines in arginine-dependent colon carcinogenesis in Apc(Min) (/+) mice by Yerushalmi, Hagit F, Besselsen, David G, Ignatenko, Natalia A, Blohm-Mangone, Karen A, Padilla-Torres, Jose L, Stringer, David E, Guillen, Jose M, Holubec, Hana, Payne, Claire M, Gerner, Eugene W

“…We evaluated the role of polyamines in arginine-dependent intestinal tumorigenesis in Apc(Min) (/+) mice. Arginine is a substrate for ornithine synthesis and…”
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Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis by Ignatenko, N.A, Besselsen, D.G, Roy, U.K.B, Stringer, D.E, Blohm-Mangone, K.A, Padilla-Torres, J.L, Guillen-R, J.M, Gerner, E.W

“…The nonsteroidal antiinflammatory drug sulindac displays chemopreventive activity in patients with familial adenomatous polyposis (FAP). Sulindac metabolites…”
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APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse by Erdman, Steven H., Ignatenko, Natalia A., Powell, Marianne B., Blohm-Mangone, Karen A., Holubec, Hana, Guillén-Rodriguez, José M., Gerner, Eugene W.

“…The colorectal mucosa of pre-symptomatic individuals with familial adenomatous polyposis (FAP) contains elevated levels of the proliferation-associated…”
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Role of polyamines in arginine-dependent colon carcinogenesis in ApcMin/+ mice by Yerushalmi, Hagit F., Besselsen, David G., Ignatenko, Natalia A., Blohm-Mangone, Karen A., Padilla-Torres, Jose L., Stringer, David E., Guillen, Jose M., Holubec, Hana, Payne, Claire M., Gerner, Eugene W.

“…We evaluated the role of polyamines in arginine‐dependent intestinal tumorigenesis in ApcMin/+ mice. Arginine is a substrate for ornithine synthesis and thus…”
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Role of c-Myc in intestinal tumorigenesis of the Apc min/+ mouse1 by Ignatenko, Natalia A, Holubec, Hana, Besselsen, David G, Blohm-Mangone, Karen A, Padilla-Torres, Jose, Nagle, Raymond B., de Alboranc, Ignacio Moreno, Guillen-R, Jose M, Gerner, Eugene W

“…The c-MYC oncogene plays an important role in tumorigenesis and is commonly highly expressed in gastrointestinal cancers. In colon cells, c-MYC is regulated by…”
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Dietary Putrescine Reduces the Anticarcinogenic Intestinal Activity of Sulindac in a Murine Model of Familial Adenomatous Polyposis by Ignatenko, Natalia A., Besselsen, David G., Basu Roy, Upal K., Stringer, David E., Blohm-Mangone, Karen A., Padilla-Torres, Jose L., Guillen-R, Jose M., Gerner, Eugene W.

“…The nonsteroidal antiinflammatory drug sulindac displays chemopreventive activity in patients with familial adenomatous polyposis (FAP) . Sulindac metabolites…”
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Role of c-Myc in intestinal tumorigenesis of the ApcMin/+ mouse by Ignatenko, Natalia A, Holubec, Hana, Besselsen, David G, Blohm-Mangone, Karen A, Padilla-Torres, Jose L, Nagle, Raymond B, de Alboránç, Ignacio Moreno, Guillen-R, Jose M, Gerner, Eugene W

“…The c-MYC oncogene plays an important role in tumorigenesis and is commonly highly expressed in gastrointestinal cancers. In colon cells, c-MYC is regulated by…”
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Role of polyamines in arginine‐dependent colon carcinogenesis in Apc Min /+ mice by Yerushalmi, Hagit F., Besselsen, David G., Ignatenko, Natalia A., Blohm‐Mangone, Karen A., Padilla‐Torres, Jose L., Stringer, David E., Guillen, Jose M., Holubec, Hana, Payne, Claire M., Gerner, Eugene W.

“…Abstract We evaluated the role of polyamines in arginine‐dependent intestinal tumorigenesis in Apc Min /+ mice. Arginine is a substrate for ornithine synthesis…”
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