Search Results - "Blode, H."

Estrogen signaling to bone is not amplitude‐modulated in adult rats by Blode, H, Erben, R.G, Kantner, I

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Investigation of bioequivalence of a new fixed-dose combination of acarbose and metformin with the corresponding loose combination as well as the drug-drug interaction potential between both drugs in healthy adult male subjects by Kim, S., Jang, I.-J., Shin, D., Shin, D. S., Yoon, S., Lim, K. S., Yu, K.-S., Li, J., Zhang, H., Liu, Y., Brendel, E., Blode, H., Wang, Y.

“…Summary What is known and objective Both metformin and acarbose are recommended monotherapy and add‐on therapy in type 2 diabetes mellitus (T2DM). A fixed‐dose…”
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A 1-year pharmacokinetic investigation of a novel oral contraceptive containing drospirenone in healthy female volunteers by Blode, H., Wuttke, W., Loock, W., Röll, G., Heithecker, R.

“…Drospirenone is a novel synthetic progestogen with a pharmacological profile similar to that of natural progesterone. It has been developed in combination with…”
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A pharmacokinetic study with a low-dose oral contraceptive containing 20 μg ethinylestradiol plus 100 μg levonorgestrel by Endrikat, J., Blode, H., Gerlinger, C., Rosenbaum, P., Kuhnz, W.

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Transfer of drospirenone to breast milk after a single oral administration of 3 mg drospirenone + 30 μg ethinylestradiol to healthy lactating women by Blode, H., Foidart, J. -M., Heithecker, R.

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Transfer of drospirenone to breast milk after a single oral administration of 3 mg drospirenone + 30 microg ethinylestradiol to healthy lactating women by Blode, H, Foidart, J M, Heithecker, R

“…Drospirenone (DRSP) is a synthetic progestogen which has been developed in combination with ethinylestradiol (EE) for use as an oral contraceptive (Yasmin,…”
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DNA Adduct Formation of Selected Sex Steroids in Human Liver Slices In Vitro by Feser, W., Kerdar, R.S., Baumann, A., Körber, J., Blode, H., Kuhnz, W.

“…We report investigations into the potential of the steroid hormones chlormadinone acetate (CMA), cyproterone acetate (CPA), dexamethasone (DEX), estradiol (E…”
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Systemic availability of levonorgestrel after single oral administration of a norgestimate-containing combination oral contraceptive to 12 young women by Kuhnz, W, Blode, H, Mahler, M

“…Norgestimate is a novel progestin which undergoes both in vivo and in vitro metabolic conversions to a number of metabolites, of which the most important are…”
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Formation of DNA-adducts by selected sex steroids in rat liver by Feser, W, Kerdar, R S, Blode, H, Reimann, R

“…1. We are reporting investigations into the potential of the steroid hormones chlormadinone acetate (CMA), cyproterone acetate (CPA), ethinylestradiol (EE2)…”
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Commentary on the publication: Tucker MJ, Jones DV. Effects of cyproterone acetate in C57B1/10J mice by Schauer, G, Blode, H, Günzel, P

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Virus-induced amyloidosis in scrapie involves a change in covalent linkages in the preamyloid by Diringer, H, Blode, H, Oberdieck, U

“…Preparations of the preamyloid and the amyloid protein from normal and scrapie hamster brains show different solubilization behaviours towards Triton X-114…”
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major protein of SAF is absent from spleen and thus not an essential part of the scrapie agent by Czub, M, Braig, H.R, Blode, H, Diringer, H

“…Scrapie-associated fibrils (SAF) play a controversial role in the discussion about the nature of the scrapie agent. In purification experiments SAF can be…”
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EE-drospirenone-levomefolate calcium versus EE-drospirenone + folic acid: folate status during 24 weeks of treatment and over 20 weeks following treatment cessation by Diefenbach, Konstanze, Trummer, Dietmar, Ebert, Frank, Lissy, Michael, Koch, Manuela, Rohde, Beate, Blode, Hartmut

“…Adequate folate supplementation in the periconceptional phase is recommended to reduce the risk of neural tube defects. Oral contraceptives may provide a…”
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Coadministration of Estradiol/Drospirenone and Indomethacin Does Not Cause Hyperkalemia in Healthy Postmenopausal Women: A Randomized Open-Label Crossover Study by Schütt, Barbara, Kunz, Michael, Blode, Hartmut

“…The effect of drospirenone on plasma potassium when coadministered with nonsteroidal anti‐inflammatory drugs, such as indomethacin, is unknown. An open‐label…”
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Effect of Drospirenone on Serum Potassium and Drospirenone Pharmacokinetics in Women With Normal or Impaired Renal Function by Schürmann, Rolf, Blode, Hartmut, Benda, Norbert, Cronin, Maureen, Küfner, Andreas

“…This open‐label study investigated whether drospirenone, a novel progestin with antimineralocorticoid properties, increases the risk for hyperkalemia in…”
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A pharmacokinetic study with a low-dose oral contraceptive containing 20 μg ethinylestradiol plus 100 μg levonorgestrel by Endrikat, J., Blode, H., Gerlinger, C., Rosenbaum, P., Kuhnz, W.

“…This study investigated the pharmacokinetics of a dose-reduced oral contraceptive containing 20 μg ethinylestradiol (EE) + 100 μg levonorgestrel (LNG) in 18…”
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Differential Effects of 17b-Estradiol and of Synthetic Progestins on Aldosterone-Salt-Induced Kidney Disease by Arias-Loza, Paula-Anahi, Muehlfelder, Melanie, Elmore, Susan A, Maronpot, Robert, Hu, Kai, Blode, Hartmut, Hegele-Hartung, Christa, Fritzemeier, Karl Heinrich, Ertl, Georg, Pelzer, Theo

“…Elevated mineralocorticoid levels and female sex hormones have been shown to confer opposing effects on renal injury, but their combined effects are still…”
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Differential effects of 17beta-estradiol and of synthetic progestins on aldosterone-salt-induced kidney disease by Arias-Loza, Paula-Anahi, Muehlfelder, Melanie, Elmore, Susan A, Maronpot, Robert, Hu, Kai, Blode, Hartmut, Hegele-Hartung, Christa, Fritzemeier, Karl Heinrich, Ertl, Georg, Pelzer, Theo

“…Elevated mineralocorticoid levels and female sex hormones have been shown to confer opposing effects on renal injury, but their combined effects are still…”
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Pharmacokinetics and Pharmacodynamics of Drospirenone-Estradiol Combination Hormone Therapy Product Coadministered With Hydrochlorothiazide in Hypertensive Postmenopausal Women by Karara, Adel H., Hanes, Vladimir, Alonso, Alberto, Ni, Pingping, Poola, Nagaraju, Silang, Rose, Blode, Hartmut, Preston, Richard A.

“…The effects of combination hormone therapy of drospirenone (DRSP), a novel progestin with antialdosterone properties, and 17β‐estradiol (E2) on…”
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A pharmacokinetic study with a low-dose oral contraceptive containing 20 microg ethinylestradiol plus 100 microg levonorgestrel by Endrikat, J, Blode, H, Gerlinger, C, Rosenbaum, P, Kuhnz, W

“…This study investigated the pharmacokinetics of a dose-reduced oral contraceptive containing 20 microg ethinylestradiol (EE) + 100 microg levonorgestrel (LNG)…”
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