Search Results - "Block, AnneMarie"
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Prognostic Significance of the European LeukemiaNet Standardized System for Reporting Cytogenetic and Molecular Alterations in Adults With Acute Myeloid Leukemia
Published in Journal of clinical oncology (20-12-2012)“…To evaluate the prognostic significance of the international European LeukemiaNet (ELN) guidelines for reporting genetic alterations in acute myeloid leukemia…”
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2
Deciphering spatial genomic heterogeneity at a single cell resolution in multiple myeloma
Published in Nature communications (10-02-2022)“…Osteolytic lesions (OL) characterize symptomatic multiple myeloma. The mechanisms of how malignant plasma cells (PC) cause OL in one region while others show…”
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3
Ofatumumab plus HyperCVAD/HD‐MA induction leads to high rates of minimal residual disease negativity in patients with newly diagnosed mantle cell lymphoma: Results of a phase 2 study
Published in Cancer (15-04-2022)“…Background Ofatumumab is a humanized type 1 anti‐CD20 monoclonal antibody. Preclinical studies show improved complement‐mediated cytotoxicity (CMC) compared to…”
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4
Low 25(OH) vitamin D3 levels are associated with adverse outcome in newly diagnosed, intensively treated adult acute myeloid leukemia
Published in Cancer (15-02-2014)“…BACKGROUND Several studies have suggested that low 25(OH) vitamin D3 levels may be prognostic in some malignancies, but no studies have evaluated their impact…”
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5
Spatiotemporal assessment of immunogenomic heterogeneity in multiple myeloma
Published in Blood advances (14-03-2023)“…•Clonal heterogeneity occurs especially in patients with extramedullary MM.•Residual disease, secondary cancers, site-specific high-risk clones, and drug…”
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6
Efficacy of lenalidomide in patients with chronic lymphocytic leukemia with high-risk cytogenetics
Published in Leukemia & lymphoma (01-01-2010)“…Patients with chronic lymphocytic lymphoma (CLL) with high-risk cytogenetics [del(11q)(q22.3) or del(17p)(p13.1)] have limited therapeutic options and their…”
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7
Image cytometry‐based detection of aneuploidy by fluorescence in situ hybridization in suspension
Published in Cytometry. Part A (01-09-2012)“…Cytogenetic abnormalities are important diagnostic and prognostic criteria for hematologic malignancies. Karyotyping and fluorescence in situ hybridization…”
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Outcome of Induction and Postremission Therapy in Younger Adults With Acute Myeloid Leukemia With Normal Karyotype: A Cancer and Leukemia Group B Study
Published in Journal of clinical oncology (20-01-2005)“…Evaluate the outcome of induction and postremission therapy in adults younger than 60 years with normal cytogenetics acute myeloid leukemia (AML). In 490…”
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9
The significance of quantifiable residual normal karyotype hematopoietic cells for toxicity and outcome
Published in Leukemia & lymphoma (01-06-2011)Get full text
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10
Smoking adversely affects survival in acute myeloid leukemia patients
Published in International journal of cancer (15-03-2012)“…Smoking adversely affects hematopoietic stem cell transplantation outcome. We asked whether smoking affected outcome of newly diagnosed acute myeloid leukemia…”
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11
Is obesity a prognostic factor for acute myeloid leukemia outcome?
Published in Annals of hematology (01-03-2012)“…Obesity adversely affects outcome in pediatric acute lymphocytic leukemia and acute myeloid leukemia (AML). We asked if obesity, measured by body mass index…”
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12
Langerhans cell sarcoma arising from chronic lymphocytic lymphoma/small lymphocytic leukemia: lineage analysis and braf v600e mutation study
Published in North American journal of medical sciences (01-06-2013)“…Background: The phenomenon that histiocytic/dendritic cell sarcomas may be transformed from lymphoproliferative diseases is dubbed ′transdifferentiation′…”
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13
Phase 1 study of arsenic trioxide, high‐dose cytarabine, and idarubicin to down‐regulate constitutive signal transducer and activator of transcription 3 activity in patients aged <60 years with acute myeloid leukemia
Published in Cancer (01-11-2011)“…BACKGROUND: Constitutive activation of signal transducer and activator of transcription‐3 (STAT3) was detected in blasts from approximately 50% of patients…”
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14
Phase II trial of clofarabine and daunorubicin as induction therapy for acute myeloid leukemia patients greater than or equal to 60 years of age
Published in Leukemia research (01-11-2013)“…Abstract We designed a phase II study evaluating the upfront combination of clofarabine and daunorubicin in acute myeloid leukemia (AML) patients ≥ 60 years…”
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15
Central review of cytogenetics is necessary for cooperative group correlative and clinical studies of adult acute leukemia : The Cancer and Leukemia Group B experience
Published in International journal of oncology (01-08-2008)“…The Cancer and Leukemia Group B has performed central review of karyotypes submitted by institutional cytogenetics laboratories from patients with acute…”
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16
Myeloid blastic transformation of myeloproliferative neoplasms—A review of 112 cases
Published in Leukemia research (01-05-2011)“…Abstract Blastic transformation of myeloproliferative neoplasms (MPN) is still poorly understood. We describe a cohort of 23 Roswell Park Cancer Institute…”
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Monoallelic and Biallelic Deletions of 13q14.3 in Chronic Lymphocytic Leukemia: FISH vs miRNA RT-qPCR Detection
Published in American journal of clinical pathology (01-04-2012)“…Deletion of 13q14.3 (del(13q)) is the most common cytogenetic abnormality in chronic lymphocytic leukemia (CLL) and implies a favorable prognosis. We explored…”
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Treating octogenarian and nonagenarian acute myeloid leukemia patients—Predictive prognostic models
Published in Cancer (01-06-2009)“…BACKGROUND: Treating the octogenarian and nonagenarian patients who have acute myeloid leukemia (AML) with intensive chemotherapy is controversial. Several…”
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19
A GOG 210 aCGH study of gain at 1q23 in endometrioid endometrial cancer in the context of racial disparity and outcome
Published in Genes chromosomes & cancer (01-09-2010)“…The goal of this study was to identify recurrent regions of genomic gain or loss in endometrial cancer of the endometrioid type in the context of racial…”
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Therapy-related myelodysplastic syndrome and acute myeloid leukemia following treatment of acute myeloid leukemia: Possible role of cytarabine
Published in Leukemia research (01-07-2008)“…Abstract Therapy-related myelodysplastic syndrome and acute myeloid leukemia (t-MDS/t-AML) have been reported only rarely following treatment of AML. We report…”
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