Search Results - "Blob, Lawrence"

Tyramine Pressor Sensitivity During Treatment With the Selegiline Transdermal System 6 mg/24 h in Healthy Subjects by Azzaro, Albert J., VanDenBerg, Chad M., Blob, Lawrence F., Kemper, Eva M., Sharoky, Melvin, Oren, Dan A., Campbell, Bryan J.

“…The oral tyramine pressor test was administered to healthy males during treatment with a selegiline transdermal system (STS; 6 mg/24 h). The tyramine…”
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Evaluation of the Potential for Pharmacodynamic and Pharmacokinetic Drug Interactions Between Selegiline Transdermal System and Two Sympathomimetic Agents (Pseudoephedrine and Phenylpropanolamine) in Healthy Volunteers by Azzaro, Albert J., VanDenBerg, Chad M., Ziemniak, John, Kemper, Eva M., Blob, Lawrence F., Campbell, Bryan J.

“…Selegiline transdermal system is a recently approved monoamine oxidase inhibitor antidepressant. Medications that inhibit monoamine oxidase type A can augment…”
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Tyramine Pharmacokinetics and Reduced Bioavailability with Food by VanDenBerg, Chad M., Blob, Lawrence F., Kemper, Eva M., Azzaro, Albert J.

“…Tyramine challenge studies have demonstrated that it requires approximately twice the amount of tyramine administered with a meal compared to administration…”
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Effects of a Tyramine-Enriched Meal on Blood Pressure Response in Healthy Male Volunteers Treated with Selegiline Transdermal System 6 mg/24 Hour by Blob, Lawrence F., Sharoky, Melvin, Campbell, Bryan J., Kemper, Eva M., Gilmor, Michelle, VanDenBerg, Chad M., Azzaro, Albert J.

“…Monoamine oxidase inhibitors are well recognized as effective antidepressant agents but are rarely used due, in part, to the risk of hypertensive crisis…”
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A Phase I, Randomized, SAD, MAD, and PK Study of Risvodetinib in Older Adults and Parkinson’s Disease by Werner, Milton H., Olanow, C. Warren, McGarry, Andrew, Meyer, Christopher, Kruger, Sydney, Klint, Carl, Pellecchia, Jacqueline, Walaker, Shannon, Ereshefsky, Larry, Blob, Lawrence, Hassman, Howard, Rodriguez, Carlos, Samara, Emil, Safirstein, Beth, Ellenbogen, Aaron

“…Background: Pre-clinical studies suggest that c-Abl activation may play an important role in the etiology of Parkinson’s disease, making c-Abl an important…”
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Tyramine pharmacokinetics and reduced unavailability with food by VanDenBerg, Chad M, Blob, Lawrence F, Kemper, Eva M, Azzaro, Albert J

“…Tyramine challenge studies have demonstrated that it requires approximately twice the amount of tyramine administered with a meal compared to administration…”
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