Search Results - "Blizzard, C A"
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Epothilone D alters normal growth, viability and microtubule dependent intracellular functions of cortical neurons in vitro
Published in Scientific reports (22-01-2020)“…Brain penetrant microtubule stabilising agents (MSAs) are being increasingly validated as potential therapeutic strategies for neurodegenerative diseases and…”
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2
Neuron–glia interactions underlie ALS-like axonal cytoskeletal pathology
Published in Neurobiology of aging (01-03-2011)“…Abstract Amyotrophic lateral sclerosis (ALS) is a devastating disorder involving loss of movement due to degeneration of motor neurons. Studies suggest that in…”
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3
Cellular dynamics underlying regeneration of damaged axons differs from initial axon development
Published in The European journal of neuroscience (01-09-2007)“…While long‐distance regeneration may be limited in mammalian species, it is becoming apparent that damaged mature neurons retain some capacity for attempted…”
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4
Excitotoxicity mediated by non-NMDA receptors causes distal axonopathy in long-term cultured spinal motor neurons
Published in The European journal of neuroscience (01-10-2007)“…Excitotoxicity has been implicated as a potential cause of neuronal degeneration in amyotrophic lateral sclerosis (ALS). It has not been clear how excitotoxic…”
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5
Epothilone D accelerates disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis
Published in Neuropathology and applied neurobiology (01-10-2018)“…Aims Degeneration of the distal neuromuscular circuitry is a hallmark pathology of Amyotrophic Lateral Sclerosis (ALS). The potential for microtubule…”
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6
Epothilone D accelerates disease progression in the SOD1 G93A mouse model of amyotrophic lateral sclerosis
Published in Neuropathology and applied neurobiology (01-10-2018)“…Degeneration of the distal neuromuscular circuitry is a hallmark pathology of Amyotrophic Lateral Sclerosis (ALS). The potential for microtubule dysfunction to…”
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7
Focal damage to the adult rat neocortex induces wound healing accompanied by axonal sprouting and dendritic structural plasticity
Published in Cerebral cortex (New York, N.Y. 1991) (01-02-2011)“…Accumulating evidence indicates that damage to the adult mammalian brain evokes an array of adaptive cellular responses and may retain a capacity for…”
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8
Geometries and charge distributions of organic ligands. I. Metal-carbon .pi. bonding and the geometry of acetylene
Published in Journal of the American Chemical Society (01-10-1968)Get full text
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CNDO-2 calculations of the electronic structure of the guanine-cytosine base pair: proton transfer in excited states
Published in Journal of theoretical biology (01-12-1969)Get more information
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10
Axonopathy and cytoskeletal disruption in degenerative diseases of the central nervous system
Published in Brain research bulletin (28-10-2009)“…Abstract There has been growing interest in the axon as the initial focus of pathological change in a number of neurodegenerative diseases of the central…”
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11
A chemistry assessment test
Published in Journal of chemical education (01-12-1975)“…The "Chemistry Assessment Test" was developed to pre-test students at the beginning of the first-year course…”
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12
Axonal shearing in mature cortical neurons induces attempted regeneration and the reestablishment of neurite polarity
Published in Brain research (10-11-2009)“…Abstract While functional recovery after injury is limited, it has become evident that the mature central nervous system does retain some ability to…”
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Individualized Methods in a Summer Freshman Chemistry Course
Published in Journal of College Science Teaching (1973)Get more information
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Individualized Methods in a Summer Freshman Chemistry Course
Published in Journal of college science teaching (01-12-1973)Get full text
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