Search Results - "Blidner, Richard A."

Caged siRNAs for Spatiotemporal Control of Gene Silencing by Casey, John P, Blidner, Richard A, Monroe, W. Todd

“…Various strategies have been employed to achieve control over delivery of siRNA molecules to intended target cells. Photocaging is one specific class of…”
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Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNA by Finkle, Justin D., Boulos, Hala, Driessen, Terri M., Lo, Christine, Blidner, Richard A., Hafez, Ashraf, Khan, Aly A., Lozac’hmeur, Ariane, McKinnon, Kelly E., Perera, Jason, Zhu, Wei, Dowlati, Afshin, White, Kevin P., Tell, Robert, Beaubier, Nike

“…Liquid biopsy is a valuable precision oncology tool that is increasingly used as a non-invasive approach to identify biomarkers, detect resistance mutations,…”
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An Integrated Next-Generation Sequencing System for Analyzing DNA Mutations, Gene Fusions, and RNA Expression in Lung Cancer by Haynes, Brian C., Blidner, Richard A., Cardwell, Robyn D., Zeigler, Robert, Gokul, Shobha, Thibert, Julie R., Chen, Liangjing, Fujimoto, Junya, Papadimitrakopoulou, Vassiliki A., Wistuba, Ignacio I., Latham, Gary J.

“…We developed and characterized a next-generation sequencing (NGS) technology for streamlined analysis of DNA and RNA using low-input, low-quality cancer…”
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Design, Optimization, and Multisite Evaluation of a Targeted Next-Generation Sequencing Assay System for Chimeric RNAs from Gene Fusions and Exon-Skipping Events in Non–Small Cell Lung Cancer by Blidner, Richard A., Haynes, Brian C., Hyter, Stephen, Schmitt, Sarah, Pessetto, Ziyan Y., Godwin, Andrew K., Su, Dan, Hurban, Patrick, van Kempen, Léon C., Aguirre, Maria L., Gokul, Shobha, Cardwell, Robyn D., Latham, Gary J.

“…Lung cancer accounts for approximately 14% of all newly diagnosed cancers and is the leading cause of cancer-related deaths. Chimeric RNA resulting from gene…”
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Photoinduced RNA interference using DMNPE-caged 2'-deoxy-2'-fluoro substituted nucleic acids in vitro and in vivo by Blidner, Richard A, Svoboda, Kurt R, Hammer, Robert P, Monroe, W Todd

“…Various chemical modifications to RNA have been incorporated in attempts to improve their pharmacological properties for RNAi interference (RNAi). Recent…”
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Fully 2′-Deoxy-2′-Fluoro Substituted Nucleic Acids Induce RNA Interference in Mammalian Cell Culture by Blidner, Richard A., Hammer, Robert P., Lopez, Mandi J., Robinson, Sandra O., Monroe, W. Todd

“…RNA interference is a phenomenon in which RNA molecules elicit potent and sequence‐specific post‐transcriptional gene silencing. Recent studies have shown that…”
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Peripapillary Scleral Thickness in Perfusion-Fixed Normal Monkey Eyes by Downs, J. Crawford, Blidner, Richard A, Bellezza, Anthony J, Thompson, Hilary W, Hart, Richard T, Burgoyne, Claude F

“…To characterize the thickness of the peripapillary sclera in perfusion-fixed normal monkey eyes so as to build accurate computational models of intraocular…”
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Abstract 2239: Comprehensive validation of RNA sequencing for clinical NGS fusion genes and RNA expression reporting by Hu, Jun, Parsons, Jerod, Mineo, Brittany, Bell, Josh SK, Malinauskas, Jenna, Drews, Joshua, Michuda, Jack, McCarter, Calvin, Dhond, Rasika, Tyndall, Jack C., Sreenivasan, Nithya, Hanjra, Sheeri, Gallagher, Shannon, Jambusaria, Ankit, Zhou, Naihui, Igartua, Catherine, Beaubier, Nike, Blidner, Richard A., Tell, Robert

“…Tumor genome sequencing has emerged as a powerful tool for identifying biomarkers for targeted cancer therapies. While DNA sequencing is a well-established…”
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An Integrated Next-Generation Sequencing System for Analyzing DNA Mutations, Gene Fusions, and RNA Expression in Lung Cancer1 by Haynes, Brian C., Blidner, Richard A., Cardwell, Robyn D., Zeigler, Robert, Gokul, Shobha, Thibert, Julie R., Chen, Liangjing, Fujimoto, Junya, Papadimitrakopoulou, Vassiliki A., Wistuba, Ignacio I., Latham, Gary J.

“…We developed and characterized a next-generation sequencing (NGS) technology for streamlined analysis of DNA and RNA using low-input, low-quality cancer…”
Get full text