Search Results - "Bleske, B E"

Pharmacotherapy for weight loss: the cardiovascular effects of the old and new agents by Walter, C. P., Bleske, B. E., Dorsch, M. P.

“…Summary What is known and objective Obesity affects approximately one‐third of the American population, and its prevalence continues to increase. It is a…”
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Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation by Shi, Jian, Wang, Xinwen, Nguyen, Jenny, Wu, Audrey H, Bleske, Barry E, Zhu, Hao-Jie

“…Sacubitril was recently approved by the Food and Drug Administration for use in combination with valsartan for the treatment of patients with heart failure…”
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Evolution and Pathophysiology of Chronic Systolic Heart Failure by Bleske, Barry E.

“…Understanding of the pathophysiology of chronic systolic heart failure evolved from a purely mechanical model to one in which a cascade of neurohormones and…”
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Guideline for the management of heart failure caused by systolic dysfunction: part II. Treatment by Chavey, 2nd, W E, Blaum, C S, Bleske, B E, Harrison, R V, Kesterson, S, Nicklas, J M

“…Several large clinical trials conducted over the past decade have shown that pharmacologic interventions can dramatically reduce the morbidity and mortality…”
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Pharmacokinetics of Torsemide in Patients with Decompensated and Compensated Congestive Heart Failure by Bleske, Barry E., Welage, Lynda S., Kramer, William G., Nicklas, John M.

“…Plasma pharmacokinetics of oral furosemide have been shown to be influenced by degree of decompensation in patients with congestive heart failure (CHF). This…”
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Effect of ethanol on defibrillation energy requirements in humans by Strickberger, S.Adam, Bleske, Barry E, Davidson, Theresa, Papasafakis, Emmanuel N, Pelosi, Frank, Michaud, Gregory F, Knight, Bradley P, Morady, Fred

“…The purpose of this double-blind study was to determine the effect of intravenous ethanol administration on defibrillation efficacy in 18 patients with an…”
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Carvedilol: Therapeutic Application and Practice Guidelines by Bleske, Barry E., Gilbert, Edward M., Munger, Mark A.

“…Current knowledge of the mechanisms contributing to progression of heart failure suggests that therapies that limit or interfere with the consequences of…”
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Diurnal Variation in Plasma Norepinephrine in Patients with Heart Failure by Bleske, Barry E., Chung, Hui-San, DiMagno, Matthew, Nicklas, John M.

“…Diurnal variation in plasma norepinephrine (PNE) levels is well documented in healthy individuals but not in patients with heart failure. Therefore, we…”
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Comparison of adrenergic agonists for the treatment of ventricular fibrillation and pulseless electrical activity by Bleske, B E, Billi, J E

“…The primary role of epinephrine for the treatment of ventricular fibrillation (VF) and pulseless electrical activity (PEA) is to increase blood flow to the…”
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Comparison of intravenous and intranasal administration of epinephrine during CPR in a canine model by Bleske, B E, Warren, E W, Rice, T L, Shea, M J, Amidon, G, Knight, P

“…Epinephrine improves coronary perfusion pressure during CPR. However, administration of epinephrine during CPR may be delayed or omitted if IV or endotracheal…”
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Variations in prothrombin time and international normalized ratio over 24 hours in warfarin-treated patients by Bleske, B E, Welage, L S, Warren, E W, Brown, M B, Shea, M J

“…To determine the variation of prothrombin times and international normalized ratio (INR) over 24 hours in humans. Prospective, parallel study…”
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The effect of dosage release formulations on the pharmacokinetics of propranolol stereoisomers in humans by Bleske, B E, Welage, L S, Rose, S, Amidon, G L, Shea, M J

“…Recent studies in dogs have suggested that the disposition of S- and R-propranolol may depend on the input rate of drug delivered to the liver. Therefore, this…”
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Epinephrine versus methoxamine in survival postventricular fibrillation and cardiopulmonary resuscitation in dogs by Bleske, B E, Chow, M S, Zhao, H, Kluger, J, Fieldman, A

“…Previous studies have indicated that methoxamine (an alpha adrenergic receptor agonist) may provide an advantage compared to epinephrine (a mixed alpha and…”
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Effect of high-dose sodium bicarbonate on the vasopressor effects of epinephrine during cardiopulmonary resuscitation by Bleske, B E, Warren, E W, Rice, T L, Gilligan, L J, Tait, A R

“…We attempted to determine the effect of extreme alkalemia induced by highdose sodium bicarbonate on the vasopressor effects of epinephrine during…”
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Effect of dose on the nasal absorption of epinephrine during cardiopulmonary resuscitation by Bleske, Barry E, Rice, Ted L, Warren, Eric W, Giacherio, Donald A, Gilligan, Lori J, Massey, Kenneth D, Tait, Alan R

“…Delay in epinephrine administration during cardiopulmonary resuscitation (CPR) due to technical difficulties in obtaining an access site may be detrimental. To…”
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An alternative sodium bicarbonate regimen during cardiac arrest and cardiopulmonary resuscitation in a canine model by Bleske, B E, Rice, T L, Warren, E W

“…We evaluated the effect of frequent, early bolus administration of low-dose sodium bicarbonate (NaHCO3) on blood gas values during ventricular fibrillation and…”
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Effect of vehicle on the nasal absorption of epinephrine during cardiopulmonary resuscitation by Bleske, B E, Rice, T L, Warren, E W, Giacherio, D A, Gilligan, L J, Massey, K D, Chrisp, C E, Tait, A R

“…We have shown in previous studies that epinephrine administered intranasally is a feasible route of administration during cardiopulmonary resuscitation (CPR)…”
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Effects of different dosages and modes of sodium bicarbonate administration during cardiopulmonary resuscitation by Bleske, B E, Chow, M S, Zhao, H, Kluger, J, Fieldman, A

“…Systemic acidosis occurs during cardiac arrest and cardiopulmonary resuscitation (CPR). The present study investigated the effect of different modes of sodium…”
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The effect of sodium bicarbonate administration on the vasopressor effect of high-dose epinephrine during cardiopulmonary resuscitation in swine by Bleske, B E, Rice, T L, Warren, E W, De Las Alas, V R, Tait, A R, Knight, P R

“…Sodium bicarbonate is administered during cardiopulmonary resuscitation (CPR) for the treatment of systemic acidemia. However, the effect of administering…”
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Comparative evaluation of the hemodynamic effects of oral cimetidine, ranitidine, and famotidine as determined by echocardiography by Welage, L S, Dunn-Kucharski, V A, Berardi, R R, Shea, M J, Dechert, R E, Bleske, B E

“…To evaluate the influence of cimetidine, ranitidine, famotidine, and placebo on cardiac performance as determined by echocardiography. Randomized, four-way…”
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