Search Results - "Blencowe, Natalie S"

What is an invasive procedure? A definition to inform study design, evidence synthesis and research tracking by Cousins, Sian, Blencowe, Natalie S, Blazeby, Jane M

“…Worldwide, there are at least 230 million invasive procedures performed annually and most of us will undergo several in our lifetime. There is therefore a need…”
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A Systematic Review of Minimally Invasive Trans-thoracic Liver Resection to Examine Intervention Description, Governance, and Outcome Reporting of an Innovative Technique by Pathak, Samir, Main, Barry G., Blencowe, Natalie S., Rees, Jonathan R. E., Robertson, Harry F., Abbadi, Reyad A. G., Blazeby, Jane M.

“…INTRODUCTION:The number of laparoscopic liver resections undertaken has increased. However, lesions located postero-superiorly are difficult to access. This…”
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Systematic review of the introduction, early phase study and evaluation of pyrocarbon proximal interphalangeal joint arthroplasty by Welford, Paul, Blencowe, Natalie S, Pardington, Emily, Jones, Conor S, Blazeby, Jane M, Main, Barry G

“…In 2002 a pyrocarbon interphalangeal joint implant was granted Food and Drug Administration approval with limited evidence of effectiveness. It is important to…”
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Development of a core data set for describing, measuring and reporting the learning curve in studies of novel invasive procedures: study protocol by Ramirez, Jozel, Hoffmann, Christin, Corrigan, Neil, Kobetic, Matthew, Macefield, Rhiannon, Elliott, Daisy, Blazeby, Jane, Potter, Shelley, Stocken, Deborah D, Avery, Kerry, Blencowe, Natalie S

“…IntroductionThe introduction of novel surgical techniques and procedures remains poorly regulated and standardised. Although the learning curve associated with…”
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Examining the application of the IDEAL framework in the reporting and evaluation of innovative invasive procedures: secondary qualitative analysis of a systematic review by Richards, Hollie Sarah, Cousins, Sian, Scroggie, Darren L, Elliott, Daisy, Macefield, Rhiannon, Hudson, Elizabeth, Mutanga, Ian Rodney, Shah, Maximilian, Alford, Natasha, Blencowe, Natalie S, Blazeby, Jane

“…ObjectivesThe development of new surgical procedures is fundamental to advancing patient care. The Idea, Developments, Exploration, Assessment and Long-term…”
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How do pilot and feasibility studies inform randomised placebo-controlled trials in surgery? A systematic review by Cousins, Sian, Gormley, Alexander, Chalmers, Katy, Campbell, Marion K, Beard, David J, Blencowe, Natalie S, Blazeby, Jane M

“…IntroductionRandomised controlled trials (RCTs) with a placebo comparator are considered the gold standard study design when evaluating healthcare…”
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Artificial intelligence as a diagnostic aid in cross-sectional radiological imaging of surgical pathology in the abdominopelvic cavity: a systematic review by Fowler, George E, Blencowe, Natalie S, Hardacre, Conor, Callaway, Mark P, Smart, Neil J, Macefield, Rhiannon

“…ObjectivesThere is emerging use of artificial intelligence (AI) models to aid diagnostic imaging. This review examined and critically appraised the application…”
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How surgical Trainee Research Collaboratives achieve success: a mixed methods study to develop trainee engagement strategies by Clement, Clare, Coulman, Karen, Heywood, Nick, Pinkney, Tom, Blazeby, Jane, Blencowe, Natalie S, Cook, Jonathan Alistair, Bulbulia, Richard, Arenas-Pinto, Alejandro, Snowdon, Claire, Hilton, Zoe, Magill, Laura, MacLennan, Graeme, Glasbey, James, Nepogodiev, Dmitri, Hardy, Victoria, Lane, J Athene

“…ObjectivesThis study aimed to understand the role of surgical Trainee Research Collaboratives (TRCs) in conducting randomised controlled trials and identify…”
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Novel device for assisted vaginal birth: using integrated qualitative case study methodology to optimise Odon Device use within a feasibility study in a maternity unit in the Southwest of England by Hotton, Emily J, Blencowe, Natalie S, Bale, Nichola, Lenguerrand, Erik, Draycott, Tim J, Crofts, Joanna F, Wade, Julia

“…ObjectiveWhen novel devices are used ‘in human’ for the first time, their optimal use is uncertain because clinicians only have experience from preclinical…”
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Understanding stage of innovation of invasive procedures and devices: protocol for a systematic review and thematic analysis by Scroggie, Darren L, Elliott, Daisy, Cousins, Sian, Avery, Kerry NL, Blazeby, Jane M, Blencowe, Natalie S

“…IntroductionSurgical innovation has generally occurred in an unstandardised manner. This has led to unnecessary exposure of patients to harm, research waste…”
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What should be included in case report forms? Development and application of novel methods to inform surgical study design: a mixed methods case study in parastomal hernia prevention by Murkin, Charlotte, Rooshenas, Leila, Smart, Neil, Daniels, I R, Pinkney, Tom, Shabbir, Jamshed, Rockall, Timothy, Bennett, Joanne, Torkington, Jared, Randall, Jonathan, Brandsma, H T, Reeves, Barnaby, Blazeby, Jane, Blencowe, Natalie S

“…ObjectivesTo describe the development and application of methods to optimise the design of case report forms (CRFs) for clinical studies evaluating surgical…”
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Artificial intelligence as a diagnostic aid in cross-sectional radiological imaging of the abdominopelvic cavity: a protocol for a systematic review by Fowler, George E, Macefield, Rhiannon C, Hardacre, Conor, Callaway, Mark P, Smart, Neil J, Blencowe, Natalie S

“…IntroductionThe application of artificial intelligence (AI) technologies as a diagnostic aid in healthcare is increasing. Benefits include applications to…”
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Discussing surgical innovation with patients: a qualitative study of surgeons’ and governance representatives’ views by Zahra, Jesmond, Paramasivan, Sangeetha, Blencowe, Natalie S, Cousins, Sian, Avery, Kerry, Mathews, Johnny, Main, Barry G, McNair, Angus G K, Hinchliffe, Robert, Blazeby, Jane M, Elliott, Daisy

“…ObjectivesLittle is known about how innovative surgical procedures are introduced and discussed with patients. This qualitative study aimed to explore…”
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Qualitative documentary analysis of guidance on information provision and consent for the introduction of innovative invasive procedures including surgeries within NHS organisations’ policies in England and Wales by Ochieng, Cynthia A, Richards, Hollie, Zahra, Jesmond, Cousins, Sian, Elliott, Daisy, Wilson, Nicholas, Paramasivan, Sangeetha, Avery, Kerry N L, Mathews, Johnny, Main, Barry G, Hinchliffe, Robert, Blencowe, Natalie S, Blazeby, Jane M

“…ObjectiveTo review guidance, included in written local UK National Health Service (NHS) organisation policies, on information provision and consent for the…”
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Randomised controlled trial to establish the clinical and cost-effectiveness of expectant management versus preoperative imaging with magnetic resonance cholangiopancreatography in patients with symptomatic gallbladder disease undergoing laparoscopic cholecystectomy at low or moderate risk of common bile duct stones (The Sunflower Study): a study protocol by Clout, Madeleine, Blazeby, Jane, Rogers, Chris, Reeves, Barnaby, Lazaroo, Michelle, Avery, Kerry, Blencowe, Natalie S, Vohra, Ravi, Jennings, Neil, Hollingworth, William, Thorn, Joanna, Jepson, Marcus, Collingwood, Jane, Guthrie, Ashley, Booth, Elizabeth, Pathak, Samir, Beckingham, Ian, Culliford, Lucy, Griffiths, Ewen A, Albazaz, Raneem, Toogood, Giles

“…IntroductionSurgery to remove the gallbladder (laparoscopic cholecystectomy (LC)) is the standard treatment for symptomatic gallbladder disease. One potential…”
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Identification of outcomes to inform the development of a core outcome set for surgical innovation: a targeted review of case studies of novel surgical devices by Wilson, Nicholas, Macefield, Rhiannon C, Hoffmann, Christin, Edmondson, Matthew J, Miller, Rachael L, Kirkham, Emily N, Blencowe, Natalie S, McNair, Angus G K, Main, Barry G, Blazeby, Jane M, Avery, Kerry N L, Potter, Shelley

“…ObjectiveOutcome selection and reporting in studies of novel surgical procedures and devices lacks standardisation, hindering safe and effective evaluation. A…”
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Surgical Training: The Impact of Changes in Curriculum and Experience by Parsons, Brian Andrew, MRCS, Blencowe, Natalie S., MRCS, Hollowood, Andrew D., FRCS, Grant, Janet R., PhD

“…Introduction Craft specialties, such as surgery, rely on practice to acquire skill. Yet recent changes in training in the United Kingdom have decreased…”
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'Trial Exegesis': Methods for Synthesizing Clinical and Patient Reported Outcome (PRO) Data in Trials to Inform Clinical Practice. A Systematic Review by McNair, Angus G K, Macefield, Rhiannon C, Blencowe, Natalie S, Brookes, Sara T, Blazeby, Jane M

“…The CONSORT extension for patient reported outcomes (PROs) aims to improve reporting, but guidance on the optimal integration with clinical data is lacking…”
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Standards of Outcome Reporting in Surgical Oncology: A Case Study in Esophageal Cancer by Blencowe, Natalie S., McNair, Angus G. K., Davis, Christopher R., Brookes, Sara T., Blazeby, Jane M.

“…Background Multimodal strategies before surgery are often used to improve outcomes, but disease progression (precluding surgical resection) and inoperability…”
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RoB 2: a revised tool for assessing risk of bias in randomised trials by Sterne, Jonathan A C, Savović, Jelena, Page, Matthew J, Elbers, Roy G, Blencowe, Natalie S, Boutron, Isabelle, Cates, Christopher J, Cheng, Hung-Yuan, Corbett, Mark S, Eldridge, Sandra M, Emberson, Jonathan R, Hernán, Miguel A, Hopewell, Sally, Hróbjartsson, Asbjørn, Junqueira, Daniela R, Jüni, Peter, Kirkham, Jamie J, Lasserson, Toby, Li, Tianjing, McAleenan, Alexandra, Reeves, Barnaby C, Shepperd, Sasha, Shrier, Ian, Stewart, Lesley A, Tilling, Kate, White, Ian R, Whiting, Penny F, Higgins, Julian P T

“…Assessment of risk of bias is regarded as an essential component of a systematic review on the effects of an intervention. The most commonly used tool for…”
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