Search Results - "Bleeker, Nicholas P."

Structure–Activity Relationship (SAR) Study of Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and the Potential of the Lead against Multidrug Resistance in Cancer Treatment by Aridoss, Gopalakrishnan, Zhou, Bo, Hermanson, David L, Bleeker, Nicholas P, Xing, Chengguo

“…Multidrug resistance (MDR) against standard therapies poses a serious challenge in cancer treatment, and there is a clinical need for new anticancer agents…”
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A Novel SERCA Inhibitor Demonstrates Synergy with Classic SERCA Inhibitors and Targets Multidrug-Resistant AML by Bleeker, Nicholas P, Cornea, Razvan L, Thomas, David D, Xing, Chengguo

“…Drug resistance exists as a major obstacle in the treatment of cancer, and drug molecules that retain effectiveness against resistant cancers are a high…”
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Structure–Activity Relationship and Molecular Mechanisms of Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and Its Analogues by Das, Sonia G, Srinivasan, Balasubramanian, Hermanson, David L, Bleeker, Nicholas P, Doshi, Jignesh M, Tang, Ruoping, Beck, William T, Xing, Chengguo

“…Multidrug resistance (MDR) in cancer is a phenomenon in which administration of a single chemotherapeutic agent causes cross-resistance of cancer cells to a…”
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Synthesis and evaluation of the anti-proliferative and NF-κB activities of a library of simplified tylophorine analogs by Niphakis, Micah J., Gay, Bryant C., Hong, Kwon Ho, Bleeker, Nicholas P., Georg, Gunda I.

“…Tylophorine and many related phenanthropiperidine alkaloids are extraordinarily potent anti-proliferative agents. Despite their impressive anti-cancer…”
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Structure–Activity Relationship (SAR) Study of Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4 H -chromene-3-carboxylate (CXL017) and the Potential of the Lead against Multidrug Resistance in Cancer Treatment by Aridoss, Gopalakrishnan, Zhou, Bo, Hermanson, David L., Bleeker, Nicholas P., Xing, Chengguo

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Synthesis and evaluation of the anti-proliferative and NF-[kappa]B activities of a library of simplified tylophorine analogs by Niphakis, Micah J, Gay, Bryant C, Hong, Kwon Ho, Bleeker, Nicholas P, Georg, Gunda I

“…Tylophorine and many related phenanthropiperidine alkaloids are extraordinarily potent anti-proliferative agents. Despite their impressive anti-cancer…”
Get full text

Structure–Activity Relationship and Molecular Mechanisms of Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4 H -chromene-3-carboxylate (CXL017) and Its Analogues by Das, Sonia G., Srinivasan, Balasubramanian, Hermanson, David L., Bleeker, Nicholas P., Doshi, Jignesh M., Tang, Ruoping, Beck, William T., Xing, Chengguo

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