Search Results - "Blease, Kelly"
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Low-pass sequencing plus imputation using avidity sequencing displays comparable imputation accuracy to sequencing by synthesis while reducing duplicates
Published in G3 : genes - genomes - genetics (07-02-2024)“…Abstract Low-pass sequencing with genotype imputation has been adopted as a cost-effective method for genotyping. The most widely used method of short-read…”
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Sequencing by avidity enables high accuracy with low reagent consumption
Published in Nature biotechnology (01-01-2024)“…We present avidity sequencing, a sequencing chemistry that separately optimizes the processes of stepping along a DNA template and that of identifying each…”
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The Space Omics and Medical Atlas (SOMA) and international astronaut biobank
Published in Nature (London) (29-08-2024)“…Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming…”
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Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight
Published in Precision clinical medicine (01-03-2024)“…Abstract Background The Inspiration4 (I4) mission, the first all-civilian orbital flight mission, investigated the physiological effects of short-duration…”
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