Search Results - "Blau, Igor W."

Chromosome 1q21 abnormalities refine outcome prediction in patients with multiple myeloma - a meta-analysis of 2,596 trial patients by Weinhold, Niels, Salwender, Hans J, Cairns, David A, Raab, Marc S, Waldron, George, Blau, Igor W, Bertsch, Uta, Hielscher, Thomas, Morgan, Gareth J, Jauch, Anna, Davies, Faith E, Hänel, Mathias, Cook, Gordon, Scheid, Christoph, Houlston, Richard, Goldschmidt, Hartmut, Jackson, Graham, Kaiser, Martin F

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CMV serostatus still has an important prognostic impact in de novo acute leukemia patients after allogeneic stem cell transplantation: a report from the Acute Leukemia Working Party of EBMT by Schmidt-Hieber, Martin, Labopin, Myriam, Beelen, Dietrich, Volin, Liisa, Ehninger, Gerhard, Finke, Jürgen, Socié, Gerard, Schwerdtfeger, Rainer, Kröger, Nicolaus, Ganser, Arnold, Niederwieser, Dietger, Polge, Emmanuelle, Blau, Igor W., Mohty, Mohamad

“…We analyzed the prognostic impact of donor and recipient cytomegalovirus (CMV) serostatus in 16 628 de novo acute leukemia patients after allogeneic stem cell…”
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Predicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel by Jiang, Sihe, Penack, Olaf, Terzer, Tobias, Schult, David, Majer-Lauterbach, Joshua, Radujkovic, Aleksandar, Blau, Igor W, Bullinger, Lars, Müller-Tidow, Carsten, Dreger, Peter, Luft, Thomas

“…No biomarker panel is established for prediction of sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD), a major complication of allogeneic stem…”
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Allogeneic hematopoietic stem cell transplantation in patients aged 60-79 years in Germany (1998-2018): a registry study by Weller, Jan Frederic, Lengerke, Claudia, Finke, Jürgen, Schetelig, Johannes, Platzbecker, Uwe, Einsele, Hermann, Schroeder, Thomas, Faul, Christoph, Stelljes, Matthias, Dreger, Peter, Blau, Igor W, Wulf, Gerald, Tischer, Johanna, Scheid, Christoph, Elmaagacli, Ahmet, Neidlinger, Helga, Flossdorf, Sarah, Bornhäuser, Martin, Bethge, Wolfgang, Fleischhauer, Katharina, Kröger, Nicolaus, De Wreede, Liesbeth C, Christopeit, Maximilian

“…Incidences of diseases treated with transplantation frequently peak at higher age. The contribution of age to total risk of transplantation has not been…”
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Molecular Long-Term Analysis of the GMMG-HD4 Trial in Multiple Myeloma-Patterns of Association of Chromosomal Aberrations with Response and Proliferation Determining Survival in Selecting Treatments in View of Limited Resources in Low- and Middle-Income Countries by Seckinger, Anja, Salwender, Hans, Martin, Hans, Scheid, Christof, Hielscher, Thomas, Bertsch, Uta, Hummel, Manuela, Jauch, Anna, Knauf, Wolfgang, Emde-Rajaratnam, Martina, Beck, Susanne, Neben, Kai, Dührig, Jan, Lindemann, Walter, Schmidt-Wolf, Ingo G H, Hänel, Mathias, Blau, Igor W, Weisel, Katja, Weinhold, Niels, Raab, Marc S, Goldschmidt, Hartmut, Choon-Quinones, Mimi, Hose, Dirk

“…Based on the lack of differences in progression-free and overall survival after a median follow-up of 93 months in our HOVON-65/GMMG-HD4 trial (German part; =…”
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Rationale and design of the German-speaking myeloma multicenter group (GMMG) trial HD6: a randomized phase III trial on the effect of elotuzumab in VRD induction/consolidation and lenalidomide maintenance in patients with newly diagnosed myeloma by Salwender, Hans, Bertsch, Uta, Weisel, Katja, Duerig, Jan, Kunz, Christina, Benner, Axel, Blau, Igor W, Raab, Marc Steffen, Hillengass, Jens, Hose, Dirk, Huhn, Stefanie, Hundemer, Michael, Andrulis, Mindaugas, Jauch, Anna, Seidel-Glaetzer, Andrea, Lindemann, Hans-Walter, Hensel, Manfred, Fronhoffs, Stefan, Martens, Uwe, Hansen, Timon, Wattad, Mohammed, Graeven, Ullrich, Munder, Markus, Fenk, Roland, Haenel, Mathias, Scheid, Christof, Goldschmidt, Hartmut

“…Despite major advances in therapy, multiple myeloma is still an incurable malignancy in the majority of patients. To increase survival, deeper remissions (i.e…”
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Implications and prognostic impact of mass spectrometry in patients with newly-diagnosed multiple myeloma by Mai, Elias K., Huhn, Stefanie, Miah, Kaya, Poos, Alexandra M., Scheid, Christof, Weisel, Katja C., Bertsch, Uta, Munder, Markus, Berlanga, Oscar, Hose, Dirk, Seckinger, Anja, Jauch, Anna, Blau, Igor W., Hänel, Mathias, Salwender, Hans J., Benner, Axel, Raab, Marc S., Goldschmidt, Hartmut, Weinhold, Niels

“…Mass spectrometry (MS) is a promising tool for monitoring monoclonal protein in plasma cell dyscrasias. We included 480 transplant-eligible newly-diagnosed…”
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Concomitant gain of 1q21 and MYC translocation define a poor prognostic subgroup of hyperdiploid multiple myeloma by Weinhold, Niels, Kirn, Desiree, Seckinger, Anja, Hielscher, Thomas, Granzow, Martin, Bertsch, Uta, Egerer, Gerlinde, Salwender, Hans, Blau, Igor W, Weisel, Katja, Hillengass, Jens, Raab, Marc S, Hose, Dirk, Goldschmidt, Hartmut, Jauch, Anna

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Association of uric acid levels before start of conditioning with mortality after allogeneic hematopoietic stem cell transplantation - a prospective, non-interventional study of the EBMT Transplant Complication Working Party by Penack, Olaf, Peczynski, Christophe, van der Werf, Steffie, Finke, Jürgen, Ganser, Arnold, Schoemans, Helene, Pavlu, Jiri, Niittyvuopio, Riitta, Schroyens, Wilfried, Kaynar, Leylagül, Blau, Igor W, van der Velden, Walter, Sierra, Jorge, Cortelezzi, Agostino, Wulf, Gerald, Turlure, Pascal, Rovira, Montserat, Ozkurt, Zubeydenur, Pascual-Cascon, Maria J, Moreira, Maria C, Clausen, Johannes, Greinix, Hildegard, Duarte, Rafael F, Basak, Grzegorz W

“…Uric acid is a danger signal contributing to inflammation. Its relevance to allogeneic stem cell transplantation (alloSCT) derives from preclinical models…”
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Association of Serum Ferritin Levels Before Start of Conditioning With Mortality After alloSCT - A Prospective, Non-interventional Study of the EBMT Transplant Complications Working Party by Penack, Olaf, Peczynski, Christophe, van der Werf, Steffie, Finke, Jürgen, Ganser, Arnold, Schoemans, Helene, Pavlu, Jiri, Niittyvuopio, Riitta, Schroyens, Wilfried, Kaynar, Leylagül, Blau, Igor W, van der Velden, Walter J F M, Sierra, Jorge, Cortelezzi, Agostino, Wulf, Gerald, Turlure, Pascal, Rovira, Montserrat, Ozkurt, Zubeydenur, Pascual-Cascon, Maria J, Moreira, Maria C, Clausen, Johannes, Greinix, Hildegard, Duarte, Rafael F, Basak, Grzegorz W

“…Elevated serum ferritin levels occur due to iron overload or during inflammation and macrophage activation. A correlation of high serum ferritin levels with…”
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Longitudinal fluorescence in situ hybridization reveals cytogenetic evolution in myeloma relapsing after autologous transplantation by Merz, Maximilian, Jauch, Anna, Hielscher, Thomas, Mai, Elias K, Seckinger, Anja, Hose, Dirk, Bertsch, Uta, Neben, Kai, Raab, Marc S, Salwender, Hans, Blau, Igor W, Lindemann, Hans-Walter, Schmidt-Wolf, Ingo, Scheid, Christof, Haenel, Mathias, Weisel, Katja, Goldschmidt, Hartmut, Hillengass, Jens

“…To investigate cytogenetic evolution after upfront autologous stem cell transplantation for newly diagnosed myeloma we retrospectively analyzed fluorescence…”
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Polymorphisms in CXCR3 ligands predict early CXCL9 recovery and severe chronic GVHD by Dai, Hao, Rachakonda, Sivaramakrishna P., Penack, Olaf, Blau, Igor W., Blau, Olga, Radujkovic, Aleksandar, Müller-Tidow, Carsten, Dreger, Peter, Kumar, Rajiv, Luft, Thomas

“…Chronic graft-versus-host disease (cGVHD) is a major cause of mortality and morbidity after allogeneic stem cell transplantation (alloSCT). The individual risk…”
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Viral encephalitis after allogeneic stem cell transplantation: a rare complication with distinct characteristics of different causative agents by SCHMIDT-HIEBER, Martin, SCHWENDER, Julie, NEUBURGER, Stefan, THIEL, Eckhard, BLAU, Igor W, HEINZ, Werner J, ZABELINA, Tatjana, KÜHL, Jorn S, MOUSSET, Sabine, SCHÜTTRUMPF, Silke, JUNGHANSS, Christian, SILLING, Gerda, BASARA, Nadezda

“…Limited data are available on characteristics of viral encephalitis in patients after allogeneic stem cell transplantation. We analyzed 2,628 patients after…”
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Long‐term outcome of 2‐year survivors after allogeneic hematopoietic cell transplantation for acute leukemia by Larue, Marion, Labopin, Myriam, Schroeder, Thomas, Huang, Xiao‐jun, Blau, Igor W., Schetelig, Johannes, Ganser, Arnold, Hamladji, Rose‐Marie, Bethge, Wolfgang, Kröger, Nicolaus, Socié, Gerard, Salmenniemi, Urpu, Sengeloev, Henrik, Dholaria, Bhagirathbhai, Savani, Bipin N., Nagler, Arnon, Ciceri, Fabio, Mohty, Mohamad

“…Information on late complications in patients with acute leukemia who have undergone allogeneic hematopoietic cell transplantation (HCT) is limited. We…”
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Allogeneic Hematopoietic Stem-Cell Transplantation in Patients With Hematologic Malignancies After Dose-Escalated Treosulfan/Fludarabine Conditioning by CASPER, Jochen, WOLFF, Daniel, ASCHAN, Johan, ZANDER, Axel R, KRÖGER, Nicolaus, HILGENDORF, Inken, BAUMGART, Joachim, MYLIUS, Heidrun A, PICHLMEIER, Uwe, FREUND, Mathias, KNAUF, Wolfgang, BLAU, Igor W, RUUTU, Tapani, VOLIN, Liisa, WANDT, Hannes, SCHAFER-ECKART, Kerstin, HOLOWIECKI, Jerzy, GIEBEL, Sebastian

“…Treosulfan was introduced recently as a conditioning agent for allogeneic blood stem-cell transplantation. The favorable nonhematologic toxicity profile at 3 x…”
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Association between low uric acid levels and acute graft-versus-host disease by Ostendorf, Benjamin N., Blau, Olga, Uharek, Lutz, Blau, Igor W., Penack, Olaf

“…Endogenous danger signals are increasingly recognized in the pathogenesis of graft-versus-host disease (GVHD). Uric acid (UA) is a known danger signal and is…”
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Peripheral neuropathy associated with subcutaneous or intravenous bortezomib in patients with newly diagnosed myeloma treated within the GMMG MM5 phase III trial by Merz, Maximilian, Salwender, Hans, Haenel, Mathias, Mai, Elias K, Bertsch, Uta, Kunz, Christina, Hielscher, Thomas, Blau, Igor W, Scheid, Christof, Hose, Dirk, Seckinger, Anja, Jauch, Anna, Hillengass, Jens, Raab, Marc S, Schurich, Baerbel, Munder, Markus, Brossart, Peter, Gerecke, Christian, Lindemann, Hans-Walter, Zeis, Matthias, Weisel, Katja, Duerig, Jan, Goldschmidt, Hartmut

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Intrathecal application of donor lymphocytes in leukemic meningeosis after allogeneic stem cell transplantation by Neumann, Martin, Blau, Igor W., Burmeister, Thomas, Tietze-Buerger, Carola, Blau, Olga, Gerbitz, Armin, Uharek, Lutz, Thiel, Eckhard

“…Extramedullary relapses after allogeneic stem cell transplantation, especially within the central nervous system (CNS), are not only difficult to treat but…”
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Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantation by Hütter, Gero, Nowak, Daniel, Mossner, Maximilian, Ganepola, Susanne, Müßig, Arne, Allers, Kristina, Schneider, Thomas, Hofmann, Jörg, Hofmann, Wolf K, Kücherer, Claudia, Blau, Olga, Blau, Igor W, Thiel, Eckhard

“…To infect cells, human immunodeficiency virus (HIV) binds the CD4 receptor and a chemokine coreceptor, CCR5 or CXCR4. In an HIV-infected patient with acute…”
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In vitro cytotoxicity of the novel antimyeloma agents perifosine, bortezomib and lenalidomide against different cell lines by Schmidt-Hieber, Martin, Dabrowski, Robert, Weimann, Andreas, Aicher, Babette, Lohneis, Philipp, Busse, Antonia, Thiel, Eckhard, Blau, Igor W.

“…Summary The novel AKT inhibitor perifosine, a synthetic alkylphospholipid, is currently being investigated in clinical trials for the treatment of different…”
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