Search Results - "Blatt, Alexandra"
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The Heparanase Inhibitor PG545 Attenuates Colon Cancer Initiation and Growth, Associating with Increased p21 Expression
Published in Neoplasia (New York, N.Y.) (01-03-2017)“…Abstract Heparanase activity is highly implicated in cellular invasion and tumor metastasis, a consequence of cleavage of heparan sulfate and remodeling of the…”
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Microbial Growth Inhibition by Alternating Electric Fields
Published in Antimicrobial Agents and Chemotherapy (01-10-2008)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The expression of iNOS and nitrotyrosine in colitis and colon cancer in humans
Published in Acta histochemica (01-12-2012)“…Chronic inflammation increases the risk of development of several types of malignancies including colon cancer. It also represents a paradigm for the…”
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Microbial Growth Inhibition by Alternating Electric Fields in Mice with Pseudomonas aeruginosa Lung Infection
Published in Antimicrobial Agents and Chemotherapy (01-08-2010)“…OA Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Infliximab–Tumor Necrosis Factor Complexes Elicit Formation of Anti-Drug Antibodies
Published in Gastroenterology (New York, N.Y. 1943) (01-11-2019)“…Some patients develop anti-drug antibodies (ADAs), which reduce the efficacy of infliximab, a monoclonal antibody against tumor necrosis factor (TNF), in the…”
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Anti-infliximab Antibodies with Neutralizing Capacity in Patients with Inflammatory Bowel Disease: Distinct Clinical Implications Revealed by a Novel Assay
Published in Inflammatory bowel diseases (01-07-2016)“…About 60% of infliximab (IFX)-treated patients develop antidrug antibodies (ADA), although their clinical significance remains disputed. The aim of this study…”
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Differential Serum-intestinal Dynamics of Infliximab and Adalimumab in Inflammatory Bowel Disease Patients
Published in Journal of Crohn's and colitis (14-07-2022)“…Abstract Background and Aims Therapeutic drug monitoring is used to guide anti-tumour necrosis factor [TNF] therapy. However, the associations between serum…”
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A personalized network framework reveals predictive axis of anti-TNF response across diseases
Published in Cell reports. Medicine (16-01-2024)“…Personalized treatment of complex diseases has been mostly predicated on biomarker identification of one drug-disease combination at a time. Here, we use a…”
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Su2054 PG545, a Dual Heparanase and Angiogenesis Inhibitor, Induces a Potent Anti-Tumor Effect in APCMIN/+ Mice
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2016)Get full text
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The Heparanase Inhibitor PG545 Attenuates Colon Cancer Initiation and Growth, Associating with Increased p21 Expression1
Published in Neoplasia (New York, N.Y.) (29-01-2017)“…Heparanase activity is highly implicated in cellular invasion and tumor metastasis, a consequence of cleavage of heparan sulfate and remodeling of the…”
Get full text
Journal Article