Search Results - "Blaschke, K."
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Bioorthogonal Chemical Labeling Probes Targeting Sialic Acid Isomers for N‑Glycan MALDI Imaging Mass Spectrometry of Tissues, Cells, and Biofluids
Published in Analytical chemistry (Washington) (16-05-2023)“…Sialic acid isomers attached in either α2,3 or α2,6 linkage to glycan termini confer distinct chemical, biological, and pathological properties, but they…”
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Rapid N‑Glycan Profiling of Serum and Plasma by a Novel Slide-Based Imaging Mass Spectrometry Workflow
Published in Journal of the American Society for Mass Spectrometry (02-12-2020)“…Changes in the levels and compositions of N-glycans released from serum and plasma glycoproteins have been assessed in many diseases across many large clinical…”
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Integrating age, BMI, and serum N-glycans detected by MALDI mass spectrometry to classify suspicious mammogram findings as benign lesions or breast cancer
Published in Scientific reports (02-12-2022)“…While mammograms are the standard tool for breast cancer screening, there remains challenges for mammography to effectively distinguish benign lesions from…”
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Metabolic Markers and Association of Biological Sex in Lupus Nephritis
Published in International journal of molecular sciences (01-11-2023)“…Lupus nephritis (LN) is a serious complication for many patients who develop systemic lupus erythematosus, which primarily afflicts women. Our studies to…”
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Anticancer therapy at the end of life of breast, prostate, and colorectal cancer patients
Published in Annals of oncology (01-10-2018)Get full text
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Direct N-Glycosylation Profiling of Urine and Prostatic Fluid Glycoproteins and Extracellular Vesicles
Published in Frontiers in chemistry (27-09-2021)“…Expressed prostatic secretions (EPS), also called post digital rectal exam urines, are proximal fluids of the prostate that are widely used for diagnostic and…”
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Efficient Intracellular Delivery of a Protein and a Low Molecular Weight Substance via Recombinant Polyomavirus-like Particles
Published in The Journal of biological chemistry (25-06-2004)“…Efficient encapsulation of foreign molecules like proteins and low molecular weight drugs into polyoma virus-like particles (capsoids) was achieved by the…”
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Collagen XI Nucleates Self-assembly and Limits Lateral Growth of Cartilage Fibrils
Published in The Journal of biological chemistry (07-04-2000)“…Fibrils of embryonic cartilage are heterotypic alloys formed by collagens II, IX, and XI and have a uniform diameter of ∼20 nm. The molecular basis of this…”
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Protein engineering by expressed protein ligation
Published in Methods in enzymology (2000)“…By allowing the controlled assembly of synthetic peptides and recombinant polypeptides, expressed protein ligation permits unnatural amino acids, biochemical…”
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Synthesis of Multi-Domain Proteins Using Expressed Protein Ligation: Strategies for Segmental Isotopic Labeling of Internal Regions
Published in Tetrahedron (24-11-2000)“…Here we describe how a sequential version of the protein semi-synthesis technique, Expressed Protein Ligation (EPL), can be used to assemble multiple (i.e. 3…”
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Distinct Isoforms of Chicken Decorin Contain Either One or Two Dermatan Sulfate Chains
Published in The Journal of biological chemistry (29-11-1996)“…Decorin, a member of a family of proteins with leucine-rich repeat motifs, is a widely distributed extracellular matrix proteoglycan that is thought to be…”
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1519PAnticancer therapy at the end of life of breast, prostate, and colorectal cancer patients
Published in Annals of oncology (01-10-2018)Get full text
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Glycan Imaging Mass Spectrometry: Progress in Developing Clinical Diagnostic Assays for Tissues, Biofluids, and Cells
Published in Clinics in laboratory medicine (01-06-2021)“…N-glycan imaging mass spectrometry (IMS) can rapidly and reproducibly identify changes in disease-associated N-linked glycosylation that are linked with…”
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Addressing Health Literacy Issues for Adults with Developmental Disabilities Who Have Diabetes or Weight Management Issues
Published in Journal of the American Dietetic Association (01-09-2008)“…An abstract of a study by Kemnitz et al, assisting individuals to effectively manage their diabetes and weight by teaching them to make healthy food choices,…”
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Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma
Published in Cancer research communications (01-03-2023)“…There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in…”
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Introduction of unnatural amino acids into proteins using expressed protein ligation
Published in Biopolymers (1999)“…Here we describe the results of studies designed to explore the scope and limitations of expressed protein ligation (EPL), a protein semisynthesis approach…”
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Recent Progress of the ARegPKD Registry Study on Autosomal Recessive Polycystic Kidney Disease
Published in Frontiers in pediatrics (16-02-2017)“…Autosomal recessive polycystic kidney disease (ARPKD) is a rare monogenic disease with a severe phenotype often presenting prenatally or in early childhood…”
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Relationship between angiotensinogen, leptin and blood pressure levels in young normotensive men
Published in Journal of hypertension (01-10-1998)“…BACKGROUND AND AIMSAlthough the relationship between an increase in adipose tissue and a rise in blood pressure has long been recognized, the mechanism linking…”
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Investigations on the staphylococcic toxoid, Dessau's staphysol, in staphyloderma
Published in Das Deutsche Gesundheitswesen (10-04-1952)Get more information
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The sound of operation and the acoustic attenuation of the Ohmeda Medical Giraffe OmniBed
Published in Noise & health (01-01-2011)“…The neonatal intensive care unit (NICU) is an environment that provides premature and fragile infants with health provisions needed to make a complete…”
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