Search Results - "Blaquière, Marine"
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Involvement of the FoxO1/MuRF1/Atrogin-1 Signaling Pathway in the Oxidative Stress-Induced Atrophy of Cultured Chronic Obstructive Pulmonary Disease Myotubes
Published in PloS one (15-08-2016)“…Oxidative stress is thought to be one of the most important mechanisms implicated in the muscle wasting of chronic obstructive pulmonary disease (COPD)…”
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Retinoic acid maintains human skeletal muscle progenitor cells in an immature state
Published in Cellular and molecular life sciences : CMLS (01-05-2017)“…Muscle satellite cells are resistant to cytotoxic agents, and they express several genes that confer resistance to stress, thus allowing efficient dystrophic…”
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Dual-Hit: Glyphosate exposure at NOAEL level negatively impacts birth and glia-behavioural measures in heterozygous shank3 mutants
Published in Environment international (01-10-2023)“…[Display omitted] The omnipresence of environmental contaminants represents a health danger with ramifications for adverse neurological trajectories. Here, we…”
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Impaired training-induced angiogenesis process with loss of pericyte-endothelium interactions is associated with an abnormal capillary remodelling in the skeletal muscle of COPD patients
Published in Respiratory research (05-12-2019)“…Chronic obstructive pulmonary disease (COPD) is associated with exercise intolerance and limits the functional gains in response to exercise training in…”
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5
Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature
Published in Neurobiology of disease (01-05-2018)“…Cerebrovascular dysfunction and inflammation occur in epilepsy. Here we asked whether pericytes, a pivotal cellular component of brain capillaries, undergo…”
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A pericyte‐glia scarring develops at the leaky capillaries in the hippocampus during seizure activity
Published in Epilepsia (Copenhagen) (01-07-2019)“…Objective Inflammatory cerebrovascular damage occurs in epilepsy. Here, we tested the hypothesis that a pericyte‐glia scar forms around the outer wall of…”
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Differential impact of dose-range glyphosate on locomotor behavior, neuronal activity, glio-cerebrovascular structures, and transcript regulations in zebrafish larvae
Published in Chemosphere (Oxford) (01-03-2021)“…The presence of glyphosate represents a debated ecotoxicological and health risk factor. Here, zebrafish larvae were exposed, from 1.5 to 120 h…”
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Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier
Published in mBio (04-08-2020)“…Zika virus (ZIKV) can be associated with neurological impairment in children and adults. To reach the central nervous system, viruses have to cross the…”
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Seizure activity triggers tau hyperphosphorylation and amyloidogenic pathways
Published in Epilepsia (Copenhagen) (01-04-2022)“…Objective Although epilepsies and neurodegenerative disorders show pathophysiological similarities, their direct functional associations are unclear. Here, we…”
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Oxidative stress regulates autophagy in cultured muscle cells of patients with chronic obstructive pulmonary disease
Published in Journal of cellular physiology (01-12-2018)“…The proteolytic autophagy pathway is enhanced in the lower limb muscles of patients with chronic obstructive pulmonary disease (COPD). Reactive oxygen species…”
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The GR‐ANXA1 pathway is a pathological player and a candidate target in epilepsy
Published in The FASEB journal (01-12-2019)“…Immune changes occur in experimental and clinical epilepsy. Here, we tested the hypothesis that during epileptogenesis and spontaneous recurrent seizures (SRS)…”
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Effects of a human microenvironment on the differentiation of human myoblasts
Published in Biochemical and biophysical research communications (14-05-2020)“…Myogenic differentiation mechanisms are generally assessed using a murine cell line placed in low concentrations of an animal-derived serum. To more closely…”
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13
Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress
Published in BMC biology (12-06-2018)“…Skeletal muscle atrophy is a common feature of numerous chronic pathologies and is correlated with patient mortality. The REDD1 protein is currently recognized…”
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Varying modalities of perinatal exposure to a pesticide cocktail elicit neurological adaptations in mice and zebrafish
Published in Environmental pollution (1987) (01-06-2021)“…Epidemiological indications connect maternal and developmental presence or exposure to pesticides with an increased risk for a spectrum of neurological…”
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PIEZO1 expression at the glio-vascular unit adjusts to neuroinflammation in seizure conditions
Published in Neurobiology of disease (15-10-2023)“…Mechanosensors are emerging players responding to hemodynamic and physical inputs. Their significance in the central nervous system remains relatively…”
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Neurovascular multiparametric MRI defines epileptogenic and seizure propagation regions in experimental mesiotemporal lobe epilepsy
Published in Epilepsia (Copenhagen) (01-05-2021)“…Objective Improving the identification of the epileptogenic zone and associated seizure‐spreading regions represents a significant challenge. Innovative…”
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COPD is deleterious for pericytes: implications during training-induced angiogenesis in skeletal muscle
Published in American journal of physiology. Heart and circulatory physiology (01-11-2020)“…Improvements in skeletal muscle endurance and oxygen uptake are blunted in patients with chronic obstructive pulmonary disease (COPD), possibly because of a…”
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Reduced myotube diameter, atrophic signalling and elevated oxidative stress in cultured satellite cells from COPD patients
Published in Journal of cellular and molecular medicine (01-01-2015)“…The mechanisms leading to skeletal limb muscle dysfunction in chronic obstructive pulmonary disease (COPD) have not been fully elucidated. Exhausted muscle…”
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Additional Effects of Nutritional Antioxidant Supplementation on Peripheral Muscle during Pulmonary Rehabilitation in COPD Patients: A Randomized Controlled Trial
Published in Oxidative medicine and cellular longevity (01-01-2019)“…Background. Skeletal muscle dysfunction in patients with chronic obstructive pulmonary disease (COPD) is not fully reversed by exercise training. Antioxidants…”
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Robust and Gradient Thickness Porous Membranes for In Vitro Modeling of Physiological Barriers
Published in Advanced materials technologies (01-12-2020)“…Porous membranes are fundamental elements for tissue‐chip barrier and co‐culture models. However, the exaggerated thickness of commonly available membranes may…”
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