Search Results - "Blank, Ulrika"

TGF-β signaling in the control of hematopoietic stem cells by Blank, Ulrika, Karlsson, Stefan

“…Blood is a tissue with high cellular turnover, and its production is a tightly orchestrated process that requires constant replenishment. All mature blood…”
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Signaling pathways governing stem-cell fate by Blank, Ulrika, Karlsson, Göran, Karlsson, Stefan

“…Hematopoietic stem cells (HSCs) are historically the most thoroughly characterized type of adult stem cell, and the hematopoietic system has served as a…”
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BMP signaling is required for postnatal murine hematopoietic stem cell self-renewal by Warsi, Sarah, Blank, Ulrika, Dahl, Maria, Grahn, Tan Hooi Min, Schmiderer, Ludwig, Andradottir, Silja, Karlsson, Stefan

“…Life-long production of blood from hematopoietic stem cells (HSCs) is a process of strict modulation. Intrinsic and extrinsic signals govern fate options like…”
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BMP7 promotes proliferation of nephron progenitor cells via a JNK-dependent mechanism by Blank, Ulrika, Brown, Aaron, Adams, Derek C, Karolak, Michele J, Oxburgh, Leif

“…The iterative formation of nephrons during embryonic development relies on continual replenishment of progenitor cells throughout nephrogenesis. Defining…”
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Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells by Warsi, Sarah, Dahl, Maria, Smith, Emma M K, Rydstrom, Anna, Mansell, Els, Sigurdsson, Valgardur, Sjoberg, Julia, Soneji, Shamit, Rorby, Emma, Siva, Kavitha, Grahn, Tan H M, Liu, Yang, Blank, Ulrika, Karlsson, Goran, Karlsson, Stefan

“…Even though hematopoietic stem cells (HSC) are characterized by their ability to self-renew and differentiate, they primarily reside in quiescence. Despite the…”
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Smad4 is critical for self-renewal of hematopoietic stem cells by Karlsson, Göran, Blank, Ulrika, Moody, Jennifer L, Ehinger, Mats, Singbrant, Sofie, Deng, Chu-Xia, Karlsson, Stefan

“…Members of the transforming growth factor beta (TGF-beta) superfamily of growth factors have been shown to regulate the in vitro proliferation and maintenance…”
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Human hematopoietic stem/progenitor cells overexpressing Smad4 exhibit impaired reconstitution potential in vivo by Rörby, Emma, Hägerström, Matilda Nifelt, Blank, Ulrika, Karlsson, Göran, Karlsson, Stefan

“…Hematopoietic stem cells (HSCs) constitute a rare population of tissue-specific cells that can self-renew and differentiate into all lineages of the blood cell…”
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Smad7 promotes self-renewal of hematopoietic stem cells by Blank, Ulrika, Karlsson, Goran, Moody, Jennifer L., Utsugisawa, Taiju, Magnusson, Mattias, Singbrant, Sofie, Larsson, Jonas, Karlsson, Stefan

“…The Smad-signaling pathway downstream of the transforming growth factor–β superfamily of ligands is an evolutionarily conserved signaling circuitry with…”
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Angptl4 maintains in vivo repopulation capacity of CD34+ human cord blood cells by Blank, Ulrika, Ehrnström, Birgitta, Heinz, Niels, Nilsson, Eva, Brun, Ann, Baum, Christopher, Schiedlmeier, Bernhard, Karlsson, Stefan

“…Objectives Methods to expand hematopoietic stem cells (HSCs) ex vivo encompass an attractive approach that would substantially broaden the clinical…”
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Smad5 is dispensable for adult murine hematopoiesis by Singbrant, Sofie, Moody, Jennifer L., Blank, Ulrika, Karlsson, Goran, Umans, Lieve, Zwijsen, An, Karlsson, Stefan

“…Smad5 is known to transduce intracellular signals from bone morphogenetic proteins (BMPs), which belong to the transforming growth factor-β (TGF-β) superfamily…”
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An in vivo reporter of BMP signaling in organogenesis reveals targets in the developing kidney by Blank, Ulrika, Seto, Marianne L, Adams, Derek C, Wojchowski, Don M, Karolak, Michele J, Oxburgh, Leif

“…Bone morphogenetic proteins (BMPs) regulate essential processes during organogenesis, and a functional understanding of these secreted proteins depends on…”
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Quiescence of hematopoietic stem cells and maintenance of the stem cell pool is not dependent on TGF-β signaling in vivo by Larsson, Jonas, Blank, Ulrika, Klintman, Jenny, Magnusson, Mattias, Karlsson, Stefan

“…Maintained quiescence of hematopoietic stem cells (HSCs) is of critical importance to prevent premature exhaustion of the stem cell pool under conditions of…”
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Endoglin Is Not Critical for Hematopoietic Stem Cell Engraftment and Reconstitution but Regulates Adult Erythroid Development by Moody, Jennifer L., Singbrant, Sofie, Karlsson, Göran, Blank, Ulrika, Aspling, Marie, Flygare, Johan, Bryder, David, Karlsson, Stefan

“…Endoglin is a transforming growth factor‐β (TGF‐β) accessory receptor recently identified as being highly expressed on long‐term repopulating hematopoietic…”
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Concise Review: The Bystander Effect: Mesenchymal Stem Cell‐Mediated Lung Repair by Savukinas, Ulrika Blank, Enes, Sara Rolandsson, Sjöland, Annika Andersson, Westergren‐Thorsson, Gunilla

“…Mesenchymal stem or stromal cells (MSCs), a heterogeneous subset of adult stem/progenitor cells, have surfaced as potential therapeutic units with significant…”
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A critical role for Smad4 in the self-renewal of hematopoietic stem cells by Karlsson, Göran, Blank, Ulrika, Moody, Jennifer L, Singbrant, Sofie, Karlsson, Stefan

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NON-canonical BMP signaling is required for postnatal hematopoietic stem cell self-renewal by Warsi, Sarah, Blank, Ulrika, Andradottir, Silja, Karlsson, Stefan

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Signaling via Smad2 and Smad3 is dispensable for adult murine hematopoietic stem cell function in vivo by Billing, Matilda, Rörby, Emma, Dahl, Maria, Blank, Ulrika, Andradottír, Silja, Ehinger, Mats, Karlsson, Stefan

“…Transforming growth factor-β (TGFβ) is a member of a large family of polypeptide growth factors. TGFβ signals mainly through the intracellular proteins Smad2…”
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Schlafen2 is a critical regulator of adult hematopoietic stem cells by Warsi, Sarah, Dahl, Maria, Rörby, Emma, Siva, Kavitha, Blank, Ulrika, Karlsson, Göran, Karlsson, Stefan

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The stem cell regulator PEDF is dispensable for maintenance and function of hematopoietic stem cells by Rörby, Emma, Billing, Matilda, Dahl, Maria, Warsi, Sarah, Andradottir, Silja, Miharada, Kenichi, Siva, Kavitha, Jönsson, Jan-Ingvar, Blank, Ulrika, Karlsson, Göran, Karlsson, Stefan

“…Pigment epithelium derived factor (PEDF), a ubiquitously expressed 50 kDa secreted glycoprotein, was recently discovered to regulate self-renewal of neural…”
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Schlafen2 regulates the regenerative capacity of adult HSCs by Warsi, Sarah, Dahl, Maria, Rorby, Emma, Blank, Ulrika, Karlsson, Göran, Karlsson, Stefan

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