Search Results - "Blank, Lars M"
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Recent Advances in Yeast Recombinant Biosynthesis of the Triterpenoid Protopanaxadiol and Glycosylated Derivatives Thereof
Published in Journal of agricultural and food chemistry (08-02-2023)“…Plant natural products are a seemingly endless resource for novel chemical structures. However, their extraction often results in high prices, fluctuation in…”
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Insights into cell wall disintegration of Chlorella vulgaris
Published in PloS one (14-01-2022)“…With their ability of CO2 fixation using sunlight as an energy source, algae and especially microalgae are moving into the focus for the production of proteins…”
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Towards bio-upcycling of polyethylene terephthalate
Published in Metabolic engineering (01-07-2021)“…Over 359 million tons of plastics were produced worldwide in 2018, with significant growth expected in the near future, resulting in the global challenge of…”
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Machine Learning Applications for Mass Spectrometry-Based Metabolomics
Published in Metabolites (13-06-2020)“…The metabolome of an organism depends on environmental factors and intracellular regulation and provides information about the physiological conditions…”
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(Poly)phosphate biotechnology: Envisaged contributions to a sustainable P future
Published in Microbial biotechnology (01-08-2023)“…The overall challenge of establishing a sustainable anthropogenic phosphate cycle did not change in the last decade, rather the need to act becomes ever more…”
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Determination of double bond positions in methyl ketones by gas chromatography–mass spectrometry using dimethyl disulfide derivatives
Published in Rapid communications in mass spectrometry (30-03-2023)“…Rationale Methyl ketones are of interest for the application as biofuels. The fatty acid metabolism of different microbes has been rearranged to achieve a…”
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Comparison of Three Xylose Pathways in Pseudomonas putida KT2440 for the Synthesis of Valuable Products
Published in Frontiers in bioengineering and biotechnology (17-01-2020)“…KT2440 is a well-established chassis in industrial biotechnology. To increase the substrate spectrum, we implemented three alternative xylose utilization…”
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Assessment of microbial activity by CO2 production during heating oil storage
Published in Engineering in life sciences (01-08-2022)“…Microbial activity is the driving force of the carbon cycle, including the digestion of biomass in the soil, oceans, and oil deposits. This natural diversity…”
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Enzymes for microplastic-free agricultural soils
Published in Ecotoxicology and environmental safety (15-06-2023)“…Plastic mulch films and biofertilizers (processed sewage sludge, compost or manure) have helped to increase crop yields. However, there is increasing evidence…”
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Using off-gas for insights through online monitoring of ethanol and baker’s yeast volatilome using SESI-Orbitrap MS
Published in Scientific reports (21-07-2022)“…Volatile organic compounds play an essential role in every domain of life, with diverse functions. In this study, we use novel secondary electrospray…”
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Engineering mediator-based electroactivity in the obligate aerobic bacterium Pseudomonas putida KT2440
Published in Frontiers in microbiology (10-04-2015)“…Pseudomonas putida strains are being developed as microbial production hosts for production of a range of amphiphilic and hydrophobic biochemicals. P. putida's…”
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Activation of the Glutamic Acid-Dependent Acid Resistance System in Escherichia coli BL21(DE3) Leads to Increase of the Fatty Acid Biotransformation Activity
Published in PloS one (28-09-2016)“…The biosynthesis of carboxylic acids including fatty acids from biomass is central in envisaged biorefinery concepts. The productivities are often, however,…”
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Boosting Heterologous Phenazine Production in Pseudomonas putida KT2440 Through the Exploration of the Natural Sequence Space
Published in Frontiers in microbiology (28-08-2019)“…Phenazine-1-carboxylic acid (PCA) and its derivative pyocyanin (PYO) are natural redox mediators in bioelectrochemical systems and have the potential to enable…”
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Process engineering of pH tolerant Ustilago cynodontis for efficient itaconic acid production
Published in Microbial cell factories (12-12-2019)“…Ustilago cynodontis ranks among the relatively unknown itaconate production organisms. In comparison to the well-known and established organisms like…”
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A genetic toolbox to empower Paracoccus pantotrophus DSM 2944 as a metabolically versatile SynBio chassis
Published in Microbial cell factories (15-02-2024)“…To contribute to the discovery of new microbial strains with metabolic and physiological robustness and develop them into successful chasses, Paracoccus…”
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Unraveling 1,4-Butanediol Metabolism in Pseudomonas putida KT2440
Published in Frontiers in microbiology (17-03-2020)“…Plastics, in all forms, are a ubiquitous cornerstone of modern civilization. Although humanity undoubtedly benefits from the versatility and durability of…”
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Synthetically-primed adaptation of Pseudomonas putida to a non-native substrate D-xylose
Published in Nature communications (26-03-2024)“…To broaden the substrate scope of microbial cell factories towards renewable substrates, rational genetic interventions are often combined with adaptive…”
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Elevated temperatures do not trigger a conserved metabolic network response among thermotolerant yeasts
Published in BMC microbiology (17-05-2019)“…Thermotolerance is a highly desirable trait of microbial cell factories and has been the focus of extensive research. Yeast usually tolerate only a narrow…”
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Fermentation and purification strategies for the production of betulinic acid and its lupane‐type precursors in Saccharomyces cerevisiae
Published in Biotechnology and bioengineering (01-11-2017)“…Microbial production of plant derived, biologically active compounds has the potential to provide economic and ecologic alternatives to existing low…”
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An Ustilago maydis chassis for itaconic acid production without by‐products
Published in Microbial biotechnology (01-03-2020)“…Summary Ustilago maydis is a promising yeast for the production of a range of valuable metabolites, including itaconate, malate, glycolipids and…”
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