Search Results - "Blank, Douglas A."
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Physiologically based cord clamping for infants ≥32+0 weeks gestation: A randomised clinical trial and reference percentiles for heart rate and oxygen saturation for infants ≥35+0 weeks gestation
Published in PLoS medicine (01-06-2022)“…Background Globally, the majority of newborns requiring resuscitation at birth are full term or late-preterm infants. These infants typically have their…”
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Effect of maternal oxytocin on umbilical venous and arterial blood flows during physiological-based cord clamping in preterm lambs
Published in PloS one (17-06-2021)“…Background Delayed umbilical cord clamping (UCC) after birth is thought to cause placental to infant blood transfusion, but the mechanisms are unknown. It has…”
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3
Cardiopulmonary Resuscitation of Asystolic Newborn Lambs Prior to Umbilical Cord Clamping; the Timing of Cord Clamping Matters
Published in Frontiers in physiology (30-07-2020)“…Background: Current guidelines recommend immediate umbilical cord clamping (UCC) for newborns requiring chest compressions (CCs). Physiological-based cord…”
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Lung aeration reduces blood pressure surges caused by umbilical cord milking in preterm lambs
Published in Frontiers in pediatrics (21-03-2023)“…Umbilical cord milking (UCM) at birth causes surges in arterial blood pressure and blood flow to the brain, which may explain the high risk of intraventricular…”
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Quantifying lung aeration in neonatal lambs at birth using lung ultrasound
Published in Frontiers in pediatrics (28-09-2022)“…BackgroundLung ultrasound (LUS) is a safe and non-invasive tool that can potentially assess regional lung aeration in newborn infants and reduce the need for…”
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Physiologic-Based Cord Clamping Maintains Core Temperature vs. Immediate Cord Clamping in Near-Term Lambs
Published in Frontiers in pediatrics (23-10-2020)“…Background: Physiologic-based cord clamping (PBCC) involves deferring umbilical cord clamping until after lung aeration. It is unclear if infant is at risk of…”
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Impact of the Neonatal Resuscitation Video Review program for neonatal staff: a qualitative analysis
Published in Pediatric research (04-10-2024)“…Neonatal resuscitation video review (NRVR) involves recording and reviewing resuscitations for education and quality assurance. Though NRVR has been shown to…”
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Extended period of ventilation before umbilical cord clamping at birth: A study that mis‐interprets and mis‐represents the physiology
Published in The Journal of physiology (01-09-2024)Get full text
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The physiology of delayed umbilical cord clamping at birth: let's not add to the confusion
Published in The Journal of physiology (01-08-2022)Get full text
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Haemodynamic effects of umbilical cord milking in premature sheep during the neonatal transition
Published in Archives of disease in childhood. Fetal and neonatal edition (01-11-2018)“…Umbilical cord milking (UCM) at birth may benefit preterm infants, but the physiological effects of UCM are unknown. We compared the physiological effects of…”
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Blood pressure and cerebral oxygenation with physiologically-based cord clamping: sub-study of the BabyDUCC trial
Published in Pediatric research (01-07-2024)“…Background Cord-clamping strategies may modify blood pressure (BP) and cerebral tissue oxygen saturation (rStO 2 ) immediately after birth. Methods We…”
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Lung ultrasound during newborn resuscitation predicts the need for surfactant therapy in very- and extremely preterm infants
Published in Resuscitation (01-05-2021)“…Early identification of infants requiring surfactant therapy improves outcomes. We evaluated the accuracy of delivery room lung ultrasound (LUS) to predict…”
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Baby-directed umbilical cord clamping: A feasibility study
Published in Resuscitation (01-10-2018)“…Over five percent of infants born worldwide will need help breathing after birth. Delayed cord clamping (DCC) has become the standard of care for vigorous…”
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Short, medium, and long deferral of umbilical cord clamping compared with umbilical cord milking and immediate clamping at preterm birth: a systematic review and network meta-analysis with individual participant data
Published in The Lancet (British edition) (09-12-2023)“…Deferred (also known as delayed) cord clamping can improve survival of infants born preterm (before 37 weeks of gestation), but the optimal duration of…”
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Endotracheal epinephrine at standard versus high dose for resuscitation of asystolic newborn lambs
Published in Resuscitation (01-05-2024)“…[Display omitted] •Standard-dose Endotracheal Epinephrine is ineffective in asystolic newborn lambs.•High-dose Endotracheal Epinephrine (1 mg/kg) can achieve…”
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Deferred cord clamping, cord milking, and immediate cord clamping at preterm birth: a systematic review and individual participant data meta-analysis
Published in The Lancet (British edition) (09-12-2023)“…Umbilical cord clamping strategies at preterm birth have the potential to affect important health outcomes. The aim of this study was to compare the…”
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Assessing the influence of abdominal compression on time to return of circulation during resuscitation of asphyxiated newborn lambs: a randomised preclinical study
Published in Archives of disease in childhood. Fetal and neonatal edition (01-07-2024)“…During neonatal resuscitation, the return of spontaneous circulation (ROSC) can be achieved using epinephrine which optimises coronary perfusion by increasing…”
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Comparison of intraosseous and intravenous epinephrine administration during resuscitation of asphyxiated newborn lambs
Published in Archives of disease in childhood. Fetal and neonatal edition (01-05-2022)“…Intraosseous access is recommended as a reasonable alternative for vascular access during newborn resuscitation if umbilical access is unavailable, but there…”
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Perinatal predictors of clinical instability at birth in late-preterm and term infants
Published in European journal of pediatrics (01-03-2023)“…To identify characteristics associated with delivery room clinical instability in at-risk infants. Prospective cohort study. Two perinatal centres in…”
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Rapid centralised randomisation in emergency setting trials using a smartphone
Published in European journal of pediatrics (01-08-2022)“…Randomised trials in emergency settings must quickly confirm eligibility and allocate participants to an intervention group without delaying treatment. We…”
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