Search Results - "Blaner, WS"

Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis by Xu, L, Hui, A Y, Albanis, E, Arthur, M J, O’Byrne, S M, Blaner, W S, Mukherjee, P, Friedman, S L, Eng, F J

“…Background: Hepatic stellate cells (HSCs) are a major fibrogenic cell type that contributes to collagen accumulation during chronic liver disease. With…”
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Retinoid Absorption and Storage Is Impaired in Mice Lacking Lecithin:Retinol Acyltransferase (LRAT) by O'Byrne, Sheila M., Wongsiriroj, Nuttaporn, Libien, Jenny, Vogel, Silke, Goldberg, Ira J., Baehr, Wolfgang, Palczewski, Krzysztof, Blaner, William S.

“…Lecithin:retinol acyltransferase (LRAT) is believed to be the predominant if not the sole enzyme in the body responsible for the physiologic esterification of…”
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DGAT1 deficiency decreases PPAR expression and does not lead to lipotoxicity in cardiac and skeletal muscle[S] by Liu, Li, Yu, Shuiqing, Khan, Raffay S., Ables, Gene P., Bharadwaj, Kalyani G., Hu, Yunying, Huggins, Lesley A., Eriksson, Jan W., Buckett, Linda K., Turnbull, Andrew V., Ginsberg, Henry N., Blaner, William S., Huang, Li-Shin, Goldberg, Ira J.

“…Diacylglycerol (DAG) acyl transferase 1 (Dgat1) knockout (−/−) mice are resistant to high-fat-induced obesity and insulin resistance, but the reasons are…”
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Omega-3 fatty acids: molecular approaches to optimal biological outcomes by Seo, Toru, Blaner, William S, Deckelbaum, Richard J

“…This review discusses recent advances in delineating basic mechanisms underlying the beneficial effects of omega-3 fatty acids on health and on disease. While…”
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Pathways of Vitamin A Delivery to the Embryo: Insights from a New Tunable Model of Embryonic Vitamin A Deficiency by Quadro, Loredana, Hamberger, Leora, Gottesman, Max E, Wang, Fengwei, Colantuoni, Vittorio, Blaner, William S, Mendelsohn, Cathy L

“…Circulating retinoids (vitamin A and its derivatives) are found predominantly as retinol bound to retinol-binding protein (RBP), which transports retinol from…”
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Hand-grip muscle strength, lean body mass, and plasma proteins as markers of nutritional status in patients with chronic renal failure close to start of dialysis therapy by Heimbürger, Olof, Qureshi, Abdul Rashid, Blaner, William S., Berglund, Lars, Stenvinkel, Peter

“…We studied 115 patients (69 men, 46 women) with chronic renal failure (CRF) aged younger than 70 years close to the start of dialysis therapy to assess the…”
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Impaired retinal function and vitamin A availability in mice lacking retinol-binding protein by Quadro, Loredana, Blaner, William S., Salchow, Daniel J., Vogel, Silke, Piantedosi, Roseann, Gouras, Peter, Freeman, Sarah, Cosma, Maria P., Colantuoni, Vittorio, Gottesman, Max E.

“…Retinol‐binding protein (RBP) is the sole specific transport protein for retinol (vitamin A) in the circulation, and its single known function is to deliver…”
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Targeted Disruption of Aldh1a1 (Raldh1) Provides Evidence for a Complex Mechanism of Retinoic Acid Synthesis in the Developing Retina by Fan, Xiaohong, Molotkov, Andrei, Manabe, Shin-Ichi, Donmoyer, Christine M., Deltour, Louise, Foglio, Mario H., Cuenca, Arnold E., Blaner, William S., Lipton, Stuart A., Duester, Gregg

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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An immortalized rat liver stellate cell line (HSC-T6): a new cell model for the study of retinoid metabolism in vitro by Vogel, S, Piantedosi, R, Frank, J, Lalazar, A, Rockey, D C, Friedman, S L, Blaner, W S

“…Hepatocytes and hepatic stellate cells play important roles in retinoid storage and metabolism. Hepatocytes process postprandial retinyl esters and are…”
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Cellular metabolism and actions of 13-cis-retinoic acid by Blaner, William S.

“…Retinoids (vitamin A and its derivatives) are potent substances for regulating the expression of many different genes within the body. The gene regulatory…”
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Expression and characterization of a murine enzyme able to cleave beta-carotene. The formation of retinoids by Paik, J, During, A, Harrison, E H, Mendelsohn, C L, Lai, K, Blaner, W S

“…Because animals are not able to synthesize retinoids de novo, ultimately they must derive them from dietary provitamin A carotenoids through a process known as…”
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Transplacental delivery of retinoid: the role of retinol-binding protein and lipoprotein retinyl ester by Quadro, Loredana, Hamberger, Leora, Gottesman, Max E, Colantuoni, Vittorio, Ramakrishnan, Rajasekhar, Blaner, William S

“…Retinoids are required for normal embryonic development. Both embryonic retinoid deficiency and excess result in congenital malformations. There is little…”
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Cellular Retinol-binding Protein Type III Is Needed for Retinoid Incorporation into Milk by Piantedosi, Roseann, Ghyselinck, Norbert, Blaner, William S., Vogel, Silke

“…The physiologic role(s) of cellular retinol-binding protein (CRBP)-III, an intracellular retinol-binding protein that is expressed solely in heart, muscle,…”
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Metabolism and Transactivation Activity of 13,14-Dihydroretinoic Acid by Moise, Alexander R., Kuksa, Vladimir, Blaner, William S., Baehr, Wolfgang, Palczewski, Krzysztof

“…The metabolism of vitamin A is a highly regulated process that generates essential mediators involved in the development, cellular differentiation, immunity,…”
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Increased Neonatal Mortality in Mice Lacking Cellular Retinol-binding Protein II by E, Xueping, Zhang, Liang, Lu, Jianyun, Tso, Patrick, Blaner, William S., Levin, Marc S., Li, Ellen

“…Cellular retinol-binding protein II (CRBP II) is a member of the cellular retinol-binding protein family, which is expressed primarily in the small intestine…”
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The role of extrahepatic retinol binding protein in the mobilization of retinoid stores by Quadro, Loredana, Blaner, William S., Hamberger, Leora, Novikoff, Phyllis M., Vogel, Silke, Piantedosi, Roseann, Gottesman, Max E., Colantuoni, Vittorio

“…Although the major tissue site of retinol binding protein (RBP) synthesis in the body is the liver, other sites of synthesis have been reported. The…”
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Retinoic Acid and its 4-Oxo Metabolites are Functionally Active in Human Skin Cells In Vitro by Baron, Jens M., Heise, Ruth, Blaner, William S., Neis, Mark, Joussen, Sylvia, Dreuw, Alexandra, Marquardt, Yvonne, Saurat, Jean-Hilaire, Merk, Hans F., Bickers, David R., Jugert, Frank K.

“…Retinoic acid exerts a variety of effects on gene transcription that regulate growth, differentiation, and inflammation in normal and neoplastic skin cells…”
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Evidence for independent control at the mRNA and protein levels of cellular retinol binding protein 1 in rat Sertoli cells by ESKILD, W, TRØEN, G, BLANER, W. S, NILSSON, A, HANSSON, V

“…Cellular retinol binding protein 1 (CRBP1) is the cytosolic carrier for retinol. It is expressed in many tissues, but the concentrations vary considerably. In…”
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Characterization of a New Member of the Fatty Acid-binding Protein Family That Binds All-trans-retinol by Vogel, Silke, Mendelsohn, Cathy L., Mertz, James R., Piantedosi, Roseann, Waldburger, Carey, Gottesman, Max E., Blaner, William S.

“…Cellular retinol-binding protein, type I (CRBP-I) and type II (CRBP-II) are the only members of the fatty acid-binding protein (FABP) family that process…”
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Studies of vitamin A metabolism in mouse model systems by Gottesman, Max E., Quadro, Loredana, Blaner, William S.

“…Over the past several years, discoveries from mouse genetics have had direct impact on our understanding of vitamin A metabolism. Although the metabolism of…”
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