Search Results - "Blandez, Juan F"

Delivery of miR-200c-3p Using Tumor-Targeted Mesoporous Silica Nanoparticles for Breast Cancer Therapy by Garrido-Cano, Iris, Adam-Artigues, Anna, Lameirinhas, Ana, Blandez, Juan F., Candela-Noguera, Vicente, Lluch, Ana, Bermejo, Begoña, Sancenón, Felix, Cejalvo, Juan Miguel, Martínez-Máñez, Ramón, Eroles, Pilar

“…Despite advances in breast cancer treatment, it remains the leading cause of cancer-related death in women worldwide. In this context, microRNAs have emerged…”
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Pharmacological senolysis reduces doxorubicin-induced cardiotoxicity and improves cardiac function in mice by Lérida-Viso, Araceli, Estepa- Fernández, Alejandra, Morellá-Aucejo, Ángela, Lozano-Torres, Beatriz, Alfonso, María, Blandez, Juan F., Bisbal, Viviana, Sepúlveda, Pilar, García-Fernández, Alba, Orzáez, Mar, Martínez-Máñez, Ramón

“…Many anticancer agents used in clinics induce premature senescence in healthy tissues generating accelerated aging processes and adverse side-effects in…”
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A renal clearable fluorogenic probe for in vivo β-galactosidase activity detection during aging and senolysis by Rojas-Vázquez, Sara, Lozano-Torres, Beatriz, García-Fernández, Alba, Galiana, Irene, Perez-Villalba, Ana, Martí-Rodrigo, Pablo, Palop, M. José, Domínguez, Marcia, Orzáez, Mar, Sancenón, Félix, Blandez, Juan F., Fariñas, Isabel, Martínez-Máñez, Ramón

“…Accumulation of senescent cells with age leads to tissue dysfunction and related diseases. Their detection in vivo still constitutes a challenge in aging…”
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miR‐99a‐5p modulates doxorubicin resistance via the COX‐2/ABCG2 axis in triple‐negative breast cancer: from the discovery to in vivo studies by Garrido‐Cano, Iris, Adam‐Artigues, Anna, Lameirinhas, Ana, Blandez, Juan F., Candela‐Noguera, Vicente, Rojo, Federico, Zazo, Sandra, Madoz‐Gúrpide, Juan, Lluch, Ana, Bermejo, Begoña, Sancenón, Felix, Cejalvo, Juan Miguel, Martínez‐Máñez, Ramón, Eroles, Pilar

“…Abbreviations ABCG2 ATP-binding cassette subfamily G member 2 ALT alanine transaminase AST aspartate aminotransferase ATCC American Type Culture Collection BC…”
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Chromo-fluorogenic probes for β-galactosidase detection by Lozano-Torres, Beatriz, Blandez, Juan F., Sancenón, Félix, Martínez-Máñez, Ramón

“…β -Galactosidase ( β -Gal) is a widely used enzyme as a reporter gene in the field of molecular biology which hydrolyzes the β -galactosides into…”
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A NIR fluorescent probe for the detection of renal damage based on overrepresentation of alanine aminopeptidase enzyme by Domínguez, Marcia, Meyer, Kathleen, Sancenón, Félix, Blandez, Juan F, Serrano, Manuel, Martínez-Máñez, Ramón

“…Kidney damage generates changes at the phenotypic and genotypic levels that allow its monitoring using different biomarkers in blood, urine or serum. Among…”
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Galacto‐conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity by González‐Gualda, Estela, Pàez‐Ribes, Marta, Lozano‐Torres, Beatriz, Macias, David, Wilson, Joseph R., González‐López, Cristina, Ou, Hui‐Ling, Mirón‐Barroso, Sofía, Zhang, Zhenguang, Lérida‐Viso, Araceli, Blandez, Juan F., Bernardos, Andrea, Sancenón, Félix, Rovira, Miguel, Fruk, Ljiljana, Martins, Carla P., Serrano, Manuel, Doherty, Gary J., Martínez‐Máñez, Ramón, Muñoz‐Espín, Daniel

“…Pharmacologically active compounds with preferential cytotoxic activity for senescent cells, known as senolytics, can ameliorate or even revert pathological…”
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Real‐Time In Vivo Detection of Cellular Senescence through the Controlled Release of the NIR Fluorescent Dye Nile Blue by Lozano‐Torres, Beatriz, Blandez, Juan F., Galiana, Irene, García‐Fernández, Alba, Alfonso, María, Marcos, María D., Orzáez, Mar, Sancenón, Félix, Martínez‐Máñez, Ramón

“…In vivo detection of cellular senescence is accomplished by using mesoporous silica nanoparticles loaded with the NIR‐FDA approved Nile blue (NB) dye and…”
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β‑Galactosidase-Activatable Nile Blue-Based NIR Senoprobe for the Real-Time Detection of Cellular Senescence by Lozano-Torres, Beatriz, García-Fernández, Alba, Domínguez, Marcia, Sancenón, Félix, Blandez, Juan F., Martínez-Máñez, Ramón

“…Cellular senescence is a stable cell cycle arrest in response to stress or other damage stimuli to maintain tissue homeostasis. However, the accumulation of…”
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A Two-Photon Probe Based on Naphthalimide-Styrene Fluorophore for the In Vivo Tracking of Cellular Senescence by Lozano-Torres, Beatriz, Blandez, Juan F, Galiana, Irene, Lopez-Dominguez, José A, Rovira, Miguel, Paez-Ribes, Marta, González-Gualda, Estela, Muñoz-Espín, Daniel, Serrano, Manuel, Sancenón, Félix, Martínez-Máñez, Ramón

“…Cellular senescence is a state of stable cell cycle arrest that can negatively affect the regenerative capacities of tissues and can contribute to inflammation…”
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Copper Nanoparticles Supported on Doped Graphenes as Catalyst for the Dehydrogenative Coupling of Silanes and Alcohols by Blandez, Juan F., Primo, Ana, Asiri, Abdullah M., Álvaro, Mercedes, García, Hermenegildo

“…Copper nanoparticles (NPs) supported on a series of undoped and doped graphene materials (Gs) have been obtained by pyrolysis of alginate or chitosan…”
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Influence of functionalization of terephthalate linker on the catalytic activity of UiO-66 for epoxide ring opening by Blandez, Juan F., Santiago-Portillo, Andrea, Navalón, Sergio, Giménez-Marqués, Mónica, Álvaro, Mercedes, Horcajada, Patricia, García, Hermenegildo

“…[Display omitted] •UiO–66s with substituents on the terephthalate (H, Br, Cl, NO2 and SO3H) linker were prepared.•The reaction tested with epoxide ring…”
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High catalytic activity of oriented 2.0.0 copper(I) oxide grown on graphene film by Primo, Ana, Esteve-Adell, Ivan, Blandez, Juan F., Dhakshinamoorthy, Amarajothi, Álvaro, Mercedes, Candu, Natalia, Coman, Simona M., Parvulescu, Vasile I., García, Hermenegildo

“…Metal oxide nanoparticles supported on graphene exhibit high catalytic activity for oxidation, reduction and coupling reactions. Here we show that pyrolysis at…”
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Correction to “β-Galactosidase-Activatable Nile Blue-Based NIR Senoprobe for the Real-Time Detection of Cellular Senescence” by Lozano-Torres, Beatriz, García-Fernández, Alba, Domínguez, Marcia, Sancenón, Félix, Blandez, Juan F., Martínez-Máñez, Ramón

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N‐Hydroxyphthalimide Anchored on Diamond Nanoparticles as a Selective Heterogeneous Metal‐free Oxidation Catalyst of Benzylic Hydrocarbons and Cyclic Alkenes by Molecular O2 by Blandez, Juan F., Navalón, Sergio, Álvaro, Mercedes, García, Hermenegildo

“…N‐hydroxyphthalimide (NHPI) derived from trimellitic anhydride has been covalently anchored (4 wt %) through ester bonds to the surface of commercial diamond…”
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Combination of palbociclib with navitoclax based-therapies enhances in vivo antitumoral activity in triple-negative breast cancer by Estepa-Fernández, Alejandra, García-Fernández, Alba, Lérida-Viso, Araceli, Blandez, Juan F., Galiana, Irene, Sancenon-Galarza, Félix, Orzáez, Mar, Martínez-Máñez, Ramón

“…Triple-negative breast cancer (TNBC) is a very aggressive subtype of breast cancer with a poor prognosis and limited effective therapeutic options. Induction…”
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Nickel nanoparticles supported on graphene as catalysts for aldehyde hydrosilylation by Blandez, Juan F., Esteve-Adell, Iván, Primo, Ana, Alvaro, Mercedes, García, Hermenegildo

“…[Display omitted] •Nickel nanoparticles (4nm) have been supported on graphenes.•Ni/G is a suitable catalyst for hydrosilylation of aldehydes.•Hydrosilylation…”
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Electro-responsive films containing voltage responsive gated mesoporous silica nanoparticles grafted onto PEDOT-based conducting polymer by García-Fernández, Alba, Lozano-Torres, Beatriz, Blandez, Juan F., Monreal-Trigo, Javier, Soto, Juan, Collazos-Castro, Jorge E., Alcañiz, Miguel, Marcos, María D., Sancenón, Félix, Martínez-Máñez, Ramón

“…The characteristics and electromechanical properties of conductive polymers together to their biocompatibility have boosted their application as a suitable…”
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Lipofuscin labeling through biorthogonal strain‐promoted azide‐alkyne cycloaddition for the detection of senescent cells by Lozano‐Torres, Beatriz, Blandez, Juan F., García‐Fernández, Alba, Sancenón, Félix, Martínez‐Máñez, Ramón

“…A new method for senescent cell detection is described, which is based on lipofuscin labeling with a fluorescent reporter through a biorthogonal…”
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Graphenes as Metal-free Catalysts for the Oxidative Depolymerization of Lignin Models by Blandez, Juan F., Navalón, Sergio, Alvaro, Mercedes, Garcia, Hermenegildo

“…Graphene oxide promotes the oxidative degradation of α‐guaiacylglycerol‐β‐guaiacyl ether, a lignin model compound, in different solvents including…”
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