Search Results - "Blanco, Juan F"
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Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: multicenter randomized controlled clinical trial (phase I/II)
Published in Journal of translational medicine (26-08-2016)“…Mesenchymal stromal cells are a promising option to treat knee osteoarthritis. Their safety and usefulness must be confirmed and the optimal dose established…”
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30-day mortality after hip fracture surgery: Influence of postoperative factors
Published in PloS one (16-02-2021)“…The 30-day mortality rate after hip fracture surgery has been considered as an indirect indicator of the quality of care. The aim of this work is to analyse…”
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Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: long-term follow up of a multicenter randomized controlled clinical trial (phase I/II)
Published in Journal of translational medicine (31-07-2018)“…Mesenchymal stromal cells (MSCs) are a promising option to treat knee osteoarthritis (OA). Their safety and usefulness have been reported in several short-term…”
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Phase II multicenter randomized controlled clinical trial on the efficacy of intra-articular injection of autologous bone marrow mesenchymal stem cells with platelet rich plasma for the treatment of knee osteoarthritis
Published in Journal of translational medicine (18-09-2020)“…Mesenchymal stromal cells are a safe and promising option to treat knee osteoarthritis as previously demonstrated in different clinical trials. However, their…”
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Isolation and Characterization of Mesenchymal Stromal Cells From Human Degenerated Nucleus Pulposus: Comparison With Bone Marrow Mesenchymal Stromal Cells From the Same Subjects
Published in Spine (Philadelphia, Pa. 1976) (15-12-2010)“…To identify mesenchymal stromal cells (MSC) from degenerate human nucleus pulposus (NP) and compare them with bone marrow (BM) MSC. To test whether MSC…”
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Long-term efficacy of autologous bone marrow mesenchymal stromal cells for treatment of knee osteoarthritis
Published in Journal of translational medicine (11-12-2021)“…Knee osteoarthritis is the most prevalent joint disease and a frequent cause of pain, functional loss and disability. Conventional treatments have demonstrated…”
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Autologous mesenchymal stem cell transplantation for spinal fusion: 10 years follow-up of a phase I/II clinical trial
Published in Stem cell research & therapy (11-04-2023)“…Posterolateral spinal fusion is the standard surgical approach for patients with degenerative disc disease. In our previously published article, we reported a…”
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Comparative analysis of the immunomodulatory capacities of human bone marrow– and adipose tissue–derived mesenchymal stromal cells from the same donor
Published in Cytotherapy (Oxford, England) (01-10-2016)“…Highlights • BM-MSCs and AT-MSCs induced a similar decrease in NK cell proliferation and cytokine secretion. • BM-MSCs show higher capacity than AT-MSCs to…”
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Analysis of the immune system of multiple myeloma patients achieving long-term disease control by multidimensional flow cytometry
Published in Haematologica (Roma) (01-01-2013)“…Multiple myeloma remains largely incurable. However, a few patients experience more than 10 years of relapse-free survival and can be considered as…”
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Preclinical Activity of the Oral Proteasome Inhibitor MLN9708 in Myeloma Bone Disease
Published in Clinical cancer research (15-03-2014)“…MLN9708 (ixazomib citrate), which hydrolyzes to pharmacologically active MLN2238 (ixazomib), is a next-generation proteasome inhibitor with demonstrated…”
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Autologous mesenchymal stromal cells embedded in tricalcium phosphate for posterolateral spinal fusion: results of a prospective phase I/II clinical trial with long-term follow-up
Published in Stem cell research & therapy (22-02-2019)“…Posterolateral spinal fusion with autologous bone graft is considered the "gold standard" for lumbar degenerative disc disease (DDD) when surgical treatment is…”
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12
Geriatric scores can predict long-term survival rate after hip fracture surgery
Published in BMC geriatrics (01-08-2019)“…The management of hip fractures is nowadays mainly performed in Orthogeriatric Units, one of whose fundamental tools is the application of geriatric scores…”
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MSCs from polytrauma patients: preliminary comparative study with MSCs from elective-surgery patients
Published in Stem cell research & therapy (11-08-2021)“…Abstract Background Polytrauma is a major clinical problem due to its impact on morbidity and mortality, especially among the younger population. Its…”
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Therapeutic potential of mesenchymal stromal/stem cells in critical‐care patients with systemic inflammatory response syndrome
Published in Clinical and translational medicine (01-01-2023)“…Background Despite notable advances in the support and treatment of patients admitted to the intensive care unit (ICU), the management of those who develop a…”
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15
Total Knee Arthroplasty for the Oldest Old
Published in Geriatrics (Basel) (04-08-2021)“…The present study describes and compares the early functional results after total knee arthroplasty (TKA) of the oldest-old population (aged over 84 years) and…”
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16
Effects of coupled natural and anthropogenic factors on the community structure of diadromous fish and shrimp species in tropical island streams
Published in Freshwater biology (01-05-2011)“…1. Overlapping river and road networks provide a framework for studying the complex interactions between natural and human systems, with river-road…”
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Bone marrow mesenchymal stem cells for improving hematopoietic function: an in vitro and in vivo model. Part 2: Effect on bone marrow microenvironment
Published in PloS one (20-10-2011)“…The aim of the present study was to determine how mesenchymal stem cells (MSC) could improve bone marrow (BM) stroma function after damage, both in vitro and…”
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Time to Surgery Reduction in Hip Fracture Patients on an Integrated Orthogeriatric Unit: A Comparative Study of Three Healthcare Models
Published in Orthopaedic surgery (01-04-2020)“…Objective To investigate the clinical efficacy of three different healthcare models (Traditional Model, Geriatric Consultant Model, and Orthogeriatric Unit…”
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Differences in pain perception, health-related quality of life, disability, mood, and sleep between Brazilian and Spanish people with chronic non-specific low back pain
Published in Revista brasileira de fisioterapia (São Carlos (São Paulo, Brazil)) (01-10-2016)“…Cultural and social factors play an important role in the development and persistence of Low Back Pain (LBP). Nevertheless, there are few studies investigating…”
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Visual function and quality of life in pseudophakic patients before and after capsulotomy
Published in European journal of ophthalmology (01-11-2012)“…Purpose. To assess the correlation between visual acuity, visual function, and health-related quality of life before and after neodymium: YAG laser posterior…”
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