Search Results - "Blanchard, Oriane"
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Clinical Validation of Targeted Next Generation Sequencing for Colon and Lung Cancers
Published in PloS one (14-09-2015)“…Recently, Next Generation Sequencing (NGS) has begun to supplant other technologies for gene mutation testing that is now required for targeted therapies…”
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Design and Validation of a Gene-Targeted, Next-Generation Sequencing Panel for Routine Diagnosis in Gliomas
Published in Cancers (04-06-2019)“…The updated 2016 World Health Organization (WHO) classification system for gliomas integrates molecular alterations and histology to provide a greater…”
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Clinical, radiological and molecular characterization of intramedullary astrocytomas
Published in Acta neuropathologica communications (08-08-2020)“…Intramedullary astrocytomas (IMAs) are rare tumors, and few studies specific to the molecular alterations of IMAs have been performed. Recently, KIAA1549-BRAF…”
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Next-generation sequencing improves the diagnosis of thyroid FNA specimens with indeterminate cytology
Published in Histopathology (01-01-2015)“…Aims The assessment of thyroid nodules is a common clinical challenge. Fine‐needle aspiration (FNA) is the standard pre‐operative tool for thyroid nodule…”
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Abstract A1-39: Clinical application of targeted next-generation sequencing for lung cancer patients: A Belgian experience
Published in Cancer research (Chicago, Ill.) (15-11-2015)“…Objective: International efforts to catalogue mutations for multiple forms of cancer coupled with the successes of targeted agents in patients with molecularly…”
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Abstract B10: Clinical validation of targeted next-generation sequencing for glioblastoma patients
Published in Cancer research (Chicago, Ill.) (01-12-2015)“…Objective: Glioblastomas (GBMs) are the most common malignant primary brain tumours in adults. These tumours are resistant to conventional treatment approaches…”
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Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience
Published in Oncotarget (17-04-2018)“…International guidelines made RAS (KRAS and NRAS) status a prerequisite for the use of anti-EGFR agents for metastatic colorectal cancer (CRC) patients. Daily,…”
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Immunohistochemistry as an accurate tool for the assessment of BRAF V600E and TP53 mutations in primary and metastatic melanoma
Published in Molecular and clinical oncology (01-12-2021)“…Metastatic melanoma is a fatal disease with poor prognosis. Ever since targeted therapy against oncogenic BRAF was approved, molecular profiling has become an…”
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Next generation sequencing : un nouvel outil de caractérisation moléculaire des tumeurs
Published in Morphologie (01-09-2015)“…Le next generation sequencing (NGS) est une technologie qui permet de séquencer simultanément des millions de courts fragments d’ADN. Cette technologie offre…”
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Intégration des données de la biologie moléculaire au diagnostic anatomopathologique des gliomes
Published in Morphologie (01-09-2015)“…Les gliomes représentent les tumeurs cérébrales primitives les plus fréquentes et regroupent différentes entités au pronostic très différent. L’examen…”
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