Search Results - "Blanchard, John A."

Inhibition of acidic sphingomyelinase reduces established hepatic fibrosis in mice by Quillin III, Ralph C., Wilson, Gregory C., Nojima, Hiroyuki, Freeman, Christopher M., Wang, Jiang, Schuster, Rebecca M., Blanchard, John A., Edwards, Michael J., Gandhi, Chandrashekhar R., Gulbins, Erich, Lentsch, Alex B.

“…Aim Liver fibrosis occurs as a result of several chronic liver diseases and leads to portal hypertension, cirrhosis and liver failure, often requiring liver…”
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Polyamines Contribute to Ethanol Withdrawal-Induced Neurotoxicity in Rat Hippocampal Slice Cultures Through Interactions With the NMDA Receptor by Gibson, D. Alex, Harris, Barton R., Prendergast, Mark A., Hart, Stewart R., Blanchard II, John A., Holley, Robert C., Pedigo, Norman W., Littleton, John M.

“…Background: Several reports demonstrate that withdrawal from long‐term ethanol exposure is associated with significant central nervous system neurotoxicity,…”
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Acamprosate Inhibits the Binding and Neurotoxic Effects of Trans-ACPD, Suggesting a Novel Site of Action at Metabotropic Glutamate Receptors by Harris, Barton R., Prendergast, Mark A., Gibson, D. Alex, Rogers, D. Trent, Blanchard, John A., Holley, Robert C., Fu, May C., Hart, Stewart R., Pedigo, Norman W., Littleton, John M.

“…Background Several reported effects of acamprosate within the glutamatergic system could result from interactions with metabotropic glutamate receptors…”
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In Vitro Effects of Ethanol Withdrawal and Spermidine on Viability of Hippocampus From Male and Female Rat by Prendergast, Mark A., Harris, Barton R., Blanchard II, John A., Mayer, Sveta, Gibson, D. Alex, Littleton, John M.

“…Background: Long‐term ethanol dependence results in neuronal adaptation that likely contributes to ethanol withdrawal‐induced central nervous system…”
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The Neurotoxicity Induced by Ethanol Withdrawal in Mature Organotypic Hippocampal Slices Might Involve Cross-Talk Between Metabotropic Glutamate Type 5 Receptors and N-Methyl-d-Aspartate Receptors by Harris, Barton R., Gibson, D. Alex, Prendergast, Mark A., Blanchard, John A., Holley, Robert C., Hart, Stewart R., Scotland, Rebecca L., Foster, Thomas C., Pedigo, Norman W., Littleton, John M.

“…Background: We recently reported that the sodium salt of acamprosate (Na‐acamprosate) demonstrates the characteristics of an antagonist at metabotropic…”
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Acamprosate, MK-801, and Ifenprodil Inhibit Neurotoxicity and Calcium Entry Induced by Ethanol Withdrawal in Organotypic Slice Cultures From Neonatal Rat Hippocampus by Mayer, Sveta, Harris, Barton R., Gibson, D. Alex, Blanchard, John A., Prendergast, Mark A., Holley, Robert C., Littleton, John

“…Background The antirelapse drug acamprosate has previously been reported to inhibit activating effects of polyamines on N‐methyl‐D‐aspartic acid receptor…”
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Antioxidants inhibit cytokine production and suppress NF-κB activation in CAPAN-1 and CAPAN-2 cell lines by BLANCHARD, John A, BARVE, Shirish, JOSHI-BARVE, Swati, TALWALKER, Ramesh, GATES, Lawrence K

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Cytokine production by CAPAN-1 and CAPAN-2 cell lines by BLANCHARD, J. A, BARVE, S, JOSHI-BARVE, S, TALWALKER, R, GATES, L. K

“…Recently, there has been a great deal of interest in the role of cytokines in acute pancreatitis. Serum levels of IL-1, IL-6, and TNF-alpha have been…”
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Opposing effects of ethanol and nicotine on hippocampal calbindin-D 28k expression by Mulholland, Patrick J, Harris, Barton R, Wilkins, Lincoln H, Self, Rachel L, Blanchard, John A, Holley, Robert C, Littleton, John M, Prendergast, Mark A

“…Long-term ethanol exposure produces multiple neuroadaptations that likely contribute to dysregulation of Ca 2+ balance and neurotoxicity during ethanol…”
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Acamprosate inhibits the binding and neurotoxic effects of trans-ACPD, suggesting a novel site of action at metabotropic glutamate receptors by HARRIS, Barton R, PRENDERGAST, Mark A, GIBSON, D. Alex, ROGERS, D. Trent, BLANCHARD, John A, HOLLEY, Robert C, FU, May C, HART, Stewart R, PEDIGO, Norman W, LITTLETON, John M

“…Several reported effects of acamprosate within the glutamatergic system could result from interactions with metabotropic glutamate receptors (mGluRs). The…”
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Antioxidants inhibit cytokine production and suppress NF-[kappa]B activation in CAPAN-1 and CAPAN-2 cell lines by Blanchard, John A, Barve, Shirish, Joshi-Barve, Swati, Talwalker, Ramesh, Gates, Lawrence K

“…Interleukin (IL) -6 and IL-8 are cytokines that have been shown to play a role in several pancreatic diseases, including acute pancreatitis, chronic…”
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Opposing effects of ethanol and nicotine on hippocampal calbindin-D28k expression by MULHOLLAND, Patrick J, HARRIS, Barton R, WILKINS, Lincoln H, SELF, Rachel L, BLANCHARD, John A, HOLLEY, Robert C, LITTLETON, John M, PRENDERGAST, Mark A

“…Long-term ethanol exposure produces multiple neuroadaptations that likely contribute to dysregulation of Ca(2+) balance and neurotoxicity during ethanol…”
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