Search Results - "Blanc, Florian E. C."
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Computational epitope map of SARS-CoV-2 spike protein
Published in PLoS computational biology (01-04-2021)“…The primary immunological target of COVID-19 vaccines is the SARS-CoV-2 spike (S) protein. S is exposed on the viral surface and mediates viral entry into the…”
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A weak coupling mechanism for the early steps of the recovery stroke of myosin VI: A free energy simulation and string method analysis
Published in PLoS computational biology (01-04-2024)“…Myosin motors use the energy of ATP to produce force and directed movement on actin by a swing of the lever-arm. ATP is hydrolysed during the off-actin…”
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Antibody accessibility determines location of spike surface mutations in SARS-CoV-2 variants
Published in PLoS computational biology (01-01-2023)“…The steady emergence of SARS-CoV-2 variants gives us a real-time view of the interplay between viral evolution and the host immune defense. The spike protein…”
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In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges
Published in Science (American Association for the Advancement of Science) (09-10-2020)“…The spike protein (S) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is required for cell entry and is the primary focus for vaccine…”
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Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments
Published in Nature structural & molecular biology (01-11-2023)“…The release of inorganic phosphate (P i ) from actin filaments constitutes a key step in their regulated turnover, which is fundamental to many cellular…”
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Mechanism of proton-powered c-ring rotation in a mitochondrial ATP synthase
Published in Proceedings of the National Academy of Sciences - PNAS (12-03-2024)“…Proton-powered c-ring rotation in mitochondrial ATP synthase is crucial to convert the transmembrane protonmotive force into torque to drive the synthesis of…”
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