Search Results - "Blais, Steven P."

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  1. 1
    The Matrix Peptide Exporter HAF-1 Signals a Mitochondrial UPR by Activating the Transcription Factor ZC376.7 in C. elegans

    The Matrix Peptide Exporter HAF-1 Signals a Mitochondrial UPR by Activating the Transcription Factor ZC376.7 in C. elegans by Haynes, Cole M., Yang, Yun, Blais, Steven P., Neubert, Thomas A., Ron, David

    Published in Molecular cell (26-02-2010)
    “…Genetic analyses previously implicated the matrix-localized protease ClpP in signaling the stress of protein misfolding in the mitochondrial matrix to activate…”
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  2. 2
    The N550K/H Mutations in FGFR2 Confer Differential Resistance to PD173074, Dovitinib, and Ponatinib ATP-Competitive Inhibitors

    The N550K/H Mutations in FGFR2 Confer Differential Resistance to PD173074, Dovitinib, and Ponatinib ATP-Competitive Inhibitors by Byron, Sara A, Chen, Huaibin, Wortmann, Andreas, Loch, David, Gartside, Michael G, Dehkhoda, Farhad, Blais, Steven P, Neubert, Thomas A, Mohammadi, Moosa, Pollock, Pamela M

    Published in Neoplasia (New York, N.Y.) (01-08-2013)
    “…Abstract We sought to identify fibroblast growth factor receptor 2 (FGFR2) kinase domain mutations that confer resistance to the pan-FGFR inhibitor, dovitinib,…”
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  3. 3
    Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases

    Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases by Chen, Huaibin, Marsiglia, William M, Cho, Min-Kyu, Huang, Zhifeng, Deng, Jingjing, Blais, Steven P, Gai, Weiming, Bhattacharya, Shibani, Neubert, Thomas A, Traaseth, Nathaniel J, Mohammadi, Moosa

    Published in eLife (06-02-2017)
    “…Receptor tyrosine kinase (RTK) signaling is tightly regulated by protein allostery within the intracellular tyrosine kinase domains. Yet the molecular…”
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  4. 4
    The N550K/H Mutations in FGFR2 Confer Differential Resistance to PD173074, Dovitinib, and Ponatinib ATP-Competitive Inhibitors12

    The N550K/H Mutations in FGFR2 Confer Differential Resistance to PD173074, Dovitinib, and Ponatinib ATP-Competitive Inhibitors12 by Byron, Sara A, Chen, Huaibin, Wortmann, Andreas, Loch, David, Gartside, Michael G, Dehkhoda, Farhad, Blais, Steven P, Neubert, Thomas A, Mohammadi, Moosa, Pollock, Pamela M

    Published in Neoplasia (New York, N.Y.) (01-08-2013)
    “…We sought to identify fibroblast growth factor receptor 2 (FGFR2) kinase domain mutations that confer resistance to the pan-FGFR inhibitor, dovitinib, and…”
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  5. 5
    The matrix peptide exporter HAF-1 signals a mitochondrial unfolded protein response by activating the transcription factor ZC376.7 in C. elegans

    The matrix peptide exporter HAF-1 signals a mitochondrial unfolded protein response by activating the transcription factor ZC376.7 in C. elegans by Haynes, Cole M., Yang, Yun, Blais, Steven P., Neubert, Thomas A., Ron, David

    Published in Molecular cell (26-02-2010)
    “…Genetic analyses previously implicated the matrix-localized protease ClpP in signaling the stress of protein misfolding in the mitochondrial matrix to activate…”
    Get full text
    Journal Article
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